Distinct signaling of coreceptors regulates specific metabolism pathways and impacts memory development in CAR T cells OU Kawalekar, RS O’Connor, JA Fraietta, L Guo, SE McGettigan, ... Immunity 44 (2), 380-390, 2016 | 1115 | 2016 |
Engineered CAR T cells targeting the cancer-associated Tn-glycoform of the membrane mucin MUC1 control adenocarcinoma AD Posey, RD Schwab, AC Boesteanu, C Steentoft, U Mandel, B Engels, ... Immunity 44 (6), 1444-1454, 2016 | 609 | 2016 |
Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation S Guedan, AD Posey Jr, C Shaw, A Wing, T Da, PR Patel, SE McGettigan, ... JCI insight 3 (1), 2018 | 519 | 2018 |
Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma LA Johnson, J Scholler, T Ohkuri, A Kosaka, PR Patel, SE McGettigan, ... Science translational medicine 7 (275), 275ra22-275ra22, 2015 | 496 | 2015 |
ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells S Guedan, X Chen, A Madar, C Carpenito, SE McGettigan, MJ Frigault, ... Blood, The Journal of the American Society of Hematology 124 (7), 1070-1080, 2014 | 426 | 2014 |
Engineering and design of chimeric antigen receptors S Guedan, H Calderon, AD Posey, MV Maus Molecular Therapy-Methods & Clinical Development 12, 145-156, 2019 | 408 | 2019 |
Safety and efficacy of intratumoral injections of chimeric antigen receptor (CAR) T cells in metastatic breast cancer J Tchou, Y Zhao, BL Levine, PJ Zhang, MM Davis, JJ Melenhorst, ... Cancer immunology research 5 (12), 1152-1161, 2017 | 384 | 2017 |
Single-cell analyses identify brain mural cells expressing CD19 as potential off-tumor targets for CAR-T immunotherapies KR Parker, D Migliorini, E Perkey, KE Yost, A Bhaduri, P Bagga, M Haris, ... Cell 183 (1), 126-142. e17, 2020 | 341 | 2020 |
Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells MJ Frigault, J Lee, MC Basil, C Carpenito, S Motohashi, J Scholler, ... Cancer immunology research 3 (4), 356-367, 2015 | 316 | 2015 |
Improving CART-cell therapy of solid tumors with oncolytic virus–driven production of a bispecific T-cell engager A Wing, CA Fajardo, AD Posey Jr, C Shaw, T Da, RM Young, R Alemany, ... Cancer immunology research 6 (5), 605-616, 2018 | 242 | 2018 |
Normal myoblast fusion requires myoferlin KR Doherty, A Cave, DB Davis, AJ Delmonte, A Posey, JU Earley, ... Oxford University Press for The Company of Biologists Limited 132 (24), 5565 …, 2005 | 237 | 2005 |
Expanding the therapeutic window for CAR T cell therapy in solid tumors: the knowns and unknowns of CAR T cell biology K Watanabe, S Kuramitsu, AD Posey Jr, CH June Frontiers in immunology 9, 2486, 2018 | 214 | 2018 |
Checkpoint blockade reverses anergy in IL-13Rα2 humanized scFv-based CAR T cells to treat murine and canine gliomas Y Yin, AC Boesteanu, ZA Binder, C Xu, RA Reid, JL Rodriguez, DR Cook, ... Molecular Therapy-Oncolytics 11, 20-38, 2018 | 149 | 2018 |
Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability S Guedan, A Madar, V Casado-Medrano, C Shaw, A Wing, F Liu, ... The Journal of clinical investigation 130 (6), 3087-3097, 2020 | 132 | 2020 |
CAR T-cell therapies in glioblastoma: a first look D Migliorini, PY Dietrich, R Stupp, GP Linette, AD Posey Jr, CH June Clinical Cancer Research 24 (3), 535-540, 2018 | 131 | 2018 |
The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion KR Doherty, AR Demonbreun, GQ Wallace, A Cave, AD Posey, K Heretis, ... Journal of Biological Chemistry 283 (29), 20252-20260, 2008 | 127 | 2008 |
Glycan-directed CAR-T cells C Steentoft, D Migliorini, TR King, U Mandel, CH June, AD Posey Jr Glycobiology 28 (9), 656-669, 2018 | 91 | 2018 |
Driving cars to the clinic for solid tumors M Castellarin, K Watanabe, CH June, CC Kloss, AD Posey Jr Gene therapy 25 (3), 165-175, 2018 | 89 | 2018 |
Ferlin proteins in myoblast fusion and muscle growth AD Posey Jr, A Demonbreun, EM McNally Current topics in developmental biology 96, 203-230, 2011 | 74 | 2011 |
Endocytic recycling proteins EHD1 and EHD2 interact with fer-1-like-5 (Fer1L5) and mediate myoblast fusion AD Posey, P Pytel, K Gardikiotes, AR Demonbreun, M Rainey, M George, ... Journal of Biological Chemistry 286 (9), 7379-7388, 2011 | 71 | 2011 |