Decision support method for the choice between batch and continuous technologies in solid drug product manufacturing K Matsunami, T Miyano, H Arai, H Nakagawa, M Hirao, H Sugiyama Industrial & Engineering Chemistry Research 57 (30), 9798-9809, 2018 | 57 | 2018 |
A large-scale experimental comparison of batch and continuous technologies in pharmaceutical tablet manufacturing using ethenzamide K Matsunami, T Nagato, K Hasegawa, H Sugiyama International journal of pharmaceutics 559, 210-219, 2019 | 39 | 2019 |
Determining key parameters of continuous wet granulation for tablet quality and productivity: A case in ethenzamide K Matsunami, T Nagato, K Hasegawa, H Sugiyama International Journal of Pharmaceutics 579, 119160, 2020 | 26 | 2020 |
Superstructure-based process synthesis and economic assessment under uncertainty for solid drug product manufacturing K Matsunami, F Sternal, K Yaginuma, S Tanabe, H Nakagawa, ... BMC Chemical Engineering 2, 1-16, 2020 | 17 | 2020 |
Analysis of the effects of process parameters on start-up operation in continuous wet granulation K Matsunami, A Ryckaert, M Peeters, S Badr, H Sugiyama, I Nopens, ... Processes 9 (9), 1502, 2021 | 12 | 2021 |
Evaluation of the influence of material properties and process parameters on granule porosity in twin-screw wet granulation M Peeters, AAB Jiménez, K Matsunami, F Stauffer, I Nopens, T De Beer International Journal of Pharmaceutics 641, 123010, 2023 | 7 | 2023 |
Linking material properties to 1D-PBM parameters towards a generic model for twin-screw wet granulation AAB Jiménez, K Matsunami, D Van Hauwermeiren, M Peeters, F Stauffer, ... Chemical Engineering Research and Design 193, 713-724, 2023 | 6 | 2023 |
Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes K Matsunami, T Miura, K Yaginuma, S Tanabe, S Badr, H Sugiyama Computers & Chemical Engineering 171, 108141, 2023 | 6 | 2023 |
Process systems engineering approaches for drug product manufacturing: from tablets to injectables H Sugiyama, K Matsunami, K Yabuta Computer Aided Chemical Engineering 40, 2785-2790, 2017 | 5 | 2017 |
Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation M Peeters, AAB Jiménez, K Matsunami, M Ghijs, E dos Santos Schultz, ... International Journal of Pharmaceutics 650, 123671, 2024 | 4 | 2024 |
Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation AAB Jiménez, K Matsunami, D Van Hauwermeiren, M Peeters, F Stauffer, ... International Journal of Pharmaceutics 640, 123040, 2023 | 4 | 2023 |
Model development and calibration of two-dimensional population balance model for twin-screw wet granulation based on particle size distribution and porosity AAB Jiménez, K Matsunami, M Ghijs, D Van Hauwermeiren, M Peeters, ... Powder Technology 419, 118334, 2023 | 4 | 2023 |
Design framework and tools for solid drug product manufacturing processes K Matsunami, S Badr, H Sugiyama Optimization of Pharmaceutical Processes, 393-412, 2022 | 4 | 2022 |
Exploring the effect of raw material properties on continuous twin-screw wet granulation manufacturability M Peeters, AAB Jiménez, K Matsunami, D Van Hauwermeiren, F Stauffer, ... International Journal of Pharmaceutics 645, 123391, 2023 | 3 | 2023 |
Determination of critical decision points for COVID-19 measures in Japan J Kim, K Matsunami, K Okamura, S Badr, H Sugiyama Scientific Reports 11 (1), 16416, 2021 | 3 | 2021 |
Economic evaluation of batch and continuous manufacturing technologies for solid drug products during clinical development K Matsunami, S Tanabe, H Nakagawa, M Hirao, H Sugiyama Computer Aided Chemical Engineering 44, 2131-2136, 2018 | 3 | 2018 |
T-shaped partial least squares for high-dosed new active pharmaceutical ingredients in continuous twin-screw wet granulation: Granule size prediction with limited material … K Matsunami, J Meyer, M Rowland, N Dawson, T De Beer, ... International Journal of Pharmaceutics 646, 123481, 2023 | 2 | 2023 |
Framework for Designing Solid Drug Product Manufacturing Processes Based on Economic and Quality Assessment K Matsunami, S Badr, H Sugiyama Computer Aided Chemical Engineering 49, 223-228, 2022 | 2 | 2022 |
Roles of mechanistic, data-driven, and hybrid modeling approaches for pharmaceutical process design and operation MR Gaddem, J Kim, K Matsunami, Y Hayashi, S Badr, H Sugiyama Current Opinion in Chemical Engineering 44, 101019, 2024 | 1 | 2024 |
Validation of model-based design of experiments for continuous wet granulation and drying K Matsunami, T Vandeputte, AAB Jiménez, M Peeters, M Ghijs, ... International Journal of Pharmaceutics 646, 123493, 2023 | 1 | 2023 |