Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness BH Stokes, SK Dhingra, K Rubiano, S Mok, J Straimer, NF Gnädig, I Deni, ... Elife 10, e66277, 2021 | 129 | 2021 |
Plasmodium vivax Sporozoite Challenge in Malaria-Naïve and Semi-Immune Colombian Volunteers M Arévalo-Herrera, DA Forero-Peña, K Rubiano, J Gómez-Hincapie, ... PLoS One 9 (6), e99754, 2014 | 58 | 2014 |
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention RL Summers, CFA Pasaje, JP Pisco, J Striepen, MR Luth, K Kumpornsin, ... Cell chemical biology 29 (2), 191-201. e8, 2022 | 51 | 2022 |
Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity M Vanaerschot, L Lucantoni, T Li, JM Combrinck, A Ruecker, TRS Kumar, ... Nature microbiology 2 (10), 1403-1414, 2017 | 50 | 2017 |
Recombinant Pvs48/45 Antigen Expressed in E. coli Generates Antibodies that Block Malaria Transmission in Anopheles albimanus Mosquitoes M Arévalo-Herrera, AF Vallejo, K Rubiano, Y Solarte, C Marin, ... PloS one 10 (3), e0119335, 2015 | 49 | 2015 |
Antibody Profiling in Naïve and Semi-immune Individuals Experimentally Challenged with Plasmodium vivax Sporozoites M Arévalo-Herrera, M Lopez-Perez, E Dotsey, A Jain, K Rubiano, ... PLoS neglected tropical diseases 10 (3), e0004563, 2016 | 39 | 2016 |
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance JM Murithi, C Pascal, J Bath, X Boulenc, NF Gnädig, CFA Pasaje, ... Science translational medicine 13 (603), eabg6013, 2021 | 34 | 2021 |
Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter AH Lee, SK Dhingra, IA Lewis, MK Singh, A Siriwardana, S Dalal, ... Scientific reports 8 (1), 13578, 2018 | 34 | 2018 |
Optimization of a Membrane Feeding Assay for Plasmodium vivax Infection in Anopheles albimanus AF Vallejo, K Rubiano, A Amado, AR Krystosik, S Herrera, ... PLoS neglected tropical diseases 10 (6), e0004807, 2016 | 32 | 2016 |
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 LE de Vries, PAM Jansen, C Barcelo, J Munro, JMJ Verhoef, CFA Pasaje, ... Nature communications 13 (1), 2158, 2022 | 23 | 2022 |
Antigenicity and immunogenicity of a novel Plasmodium vivax circumsporozoite derived synthetic vaccine construct N Céspedes, E Jiménez, M Lopez-Perez, K Rubiano, I Felger, P Alonso, ... Vaccine 32 (26), 3179-3186, 2014 | 17 | 2014 |
Activation of the Plasmodium Egress Effector Subtilisin-Like Protease 1 Is Mediated by Plasmepsin X Destruction of the Prodomain S Mukherjee, AS Nasamu, KC Rubiano, DE Goldberg Mbio 14 (2), e00673-23, 2023 | 8 | 2023 |
Exploring a Tetrahydroquinoline Antimalarial Hit from the Medicines for Malaria Pathogen Box and Identification of its Mode of Resistance as PfeEF2 B Laleu, K Rubiano, T Yeo, I Hallyburton, M Anderson, ... ChemMedChem 17 (22), e202200393, 2022 | 7 | 2022 |
Production, accumulation, and decomposition of leaf litter in a Colombian Subandean forest and neighboring areas of restoration K Rubiano-Cardona, LF Arcila-Cardona, E Jiménez-Carmona, ... Boletín Científico. Centro de Museos. Museo de Historia Natural 17 (2), 47-59, 2013 | 7 | 2013 |
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention. Cell Chem Biol 29: 191-201. e8 RL Summers, CFA Pasaje, JP Pisco, J Striepen, MR Luth, K Kumpornsin, ... | 6 | 2022 |
3-Hydroxy-propanamidines, a new class of orally active antimalarials targeting Plasmodium falciparum TC Knaab, J Held, BB Burckhardt, K Rubiano, J Okombo, T Yeo, S Mok, ... Journal of medicinal chemistry 64 (6), 3035-3047, 2021 | 6 | 2021 |
Evidence for regulation of hemoglobin metabolism and intracellular ionic flux by the Plasmodium falciparum chloroquine resistance transporter. Sci Rep 8: 13578 AH Lee, SK Dhingra, IA Lewis, MK Singh, A Siriwardana, S Dalal, ... | 6 | 2018 |
P. falciparum K13 mutations present varying degrees of artemisinin resistance and reduced fitness in African parasites BH Stokes, K Rubiano, SK Dhingra, S Mok, J Straimer, NF Gnädig, ... bioRxiv, 2021.01. 27.428390, 2021 | 4 | 2021 |
Plasmodium falciparum K13 mutations in Africa and Asia present varying degrees of artemisinin resistance and an elevated fitness cost in African parasites BH Stokes, K Rubiano, SK Dhingra, S Mok, J Straimer, NF Gnädig, ... bioRxiv, 2021 | | 2021 |
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to JM Murithi, C Pascal, J Bath, X Boulenc, NF Gnädig, CFA Pasaje, ... | | 2021 |