Activated PMN exosomes: pathogenic entities causing matrix destruction and disease in the lung KR Genschmer, DW Russell, C Lal, T Szul, PE Bratcher, BD Noerager, ... Cell 176 (1), 113-126. e15, 2019 | 361 | 2019 |
High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis R Tirouvanziam, CK Conrad, T Bottiglieri, LA Herzenberg, RB Moss, ... Proceedings of the National Academy of Sciences 103 (12), 4628-4633, 2006 | 343 | 2006 |
A randomized controlled pilot trial of oral N-acetylcysteine in children with autism AY Hardan, LK Fung, RA Libove, TV Obukhanych, S Nair, LA Herzenberg, ... Biological psychiatry 71 (11), 956-961, 2012 | 338 | 2012 |
Inflammation and infection in naive human cystic fibrosis airway grafts R Tirouvanziam, S de Bentzmann, C Hubeau, J Hinnrasky, J Jacquot, ... American journal of respiratory cell and molecular biology 23 (2), 121-127, 2000 | 311 | 2000 |
Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways R Tirouvanziam, Y Gernez, CK Conrad, RB Moss, I Schrijver, CE Dunn, ... Proceedings of the National Academy of Sciences 105 (11), 4335-4339, 2008 | 179 | 2008 |
Innate immunity of the lung: from basic mechanisms to translational medicine D Hartl, R Tirouvanziam, J Laval, CM Greene, D Habiel, L Sharma, ... Journal of innate immunity 10 (5-6), 487-501, 2018 | 141 | 2018 |
Neutrophils in chronic inflammatory airway diseases: can we target them and how? Y Gernez, R Tirouvanziam, P Chanez European Respiratory Journal 35 (3), 467-469, 2010 | 140 | 2010 |
The long-term impact of early adversity on late-life psychiatric disorders A Gershon, K Sudheimer, R Tirouvanziam, LM Williams, R O’Hara Current psychiatry reports 15, 1-9, 2013 | 126 | 2013 |
Long-term treatment with oral N-acetylcysteine: affects lung function but not sputum inflammation in cystic fibrosis subjects. A phase II randomized placebo-controlled trial C Conrad, J Lymp, V Thompson, C Dunn, Z Davies, B Chatfield, D Nichols, ... Journal of Cystic Fibrosis 14 (2), 219-227, 2015 | 125 | 2015 |
Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs M Makam, D Diaz, J Laval, Y Gernez, CK Conrad, CE Dunn, ZA Davies, ... Proceedings of the National Academy of Sciences 106 (14), 5779-5783, 2009 | 123 | 2009 |
MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia … D Dwir, B Giangreco, L Xin, L Tenenbaum, JH Cabungcal, P Steullet, ... Molecular psychiatry 25 (11), 2889-2904, 2020 | 106 | 2020 |
Primary inflammation in human cystic fibrosis small airways R Tirouvanziam, I Khazaal, B Péault American Journal of Physiology-Lung Cellular and Molecular Physiology 283 (2 …, 2002 | 99 | 2002 |
Neutrophil adaptations upon recruitment to the lung: new concepts and implications for homeostasis and disease VD Giacalone, C Margaroli, MA Mall, R Tirouvanziam International journal of molecular sciences 21 (3), 851, 2020 | 96 | 2020 |
Elastase exocytosis by airway neutrophils is associated with early lung damage in children with cystic fibrosis C Margaroli, LW Garratt, H Horati, AS Dittrich, T Rosenow, ... American Journal of Respiratory and Critical Care Medicine 199 (7), 873-881, 2019 | 96 | 2019 |
Children with neutrophil-predominant severe asthma have proinflammatory neutrophils with enhanced survival and impaired clearance JR Grunwell, ST Stephenson, R Tirouvanziam, LAS Brown, MR Brown, ... The Journal of Allergy and Clinical Immunology: In Practice 7 (2), 516-525. e6, 2019 | 81 | 2019 |
Functional Evolution of the Vertebrate Myb Gene Family: B-Myb, but Neither A-Myb nor c-Myb, Complements Drosophila Myb in Hemocytes CJ Davidson, R Tirouvanziam, LA Herzenberg, JS Lipsick Genetics 169 (1), 215-229, 2005 | 81 | 2005 |
Mature cystic fibrosis airway neutrophils suppress T cell function: evidence for a role of arginase 1 but not programmed death-ligand 1 SA Ingersoll, J Laval, OA Forrest, M Preininger, MR Brown, D Arafat, ... The Journal of Immunology 194 (11), 5520-5528, 2015 | 80 | 2015 |
Frontline Science: Pathological conditioning of human neutrophils recruited to the airway milieu in cystic fibrosis OA Forrest, SA Ingersoll, MK Preininger, J Laval, DH Limoli, MR Brown, ... Journal of leukocyte biology 104 (4), 665-675, 2018 | 78 | 2018 |
Distinct plasma profile of polar neutral amino acids, leucine, and glutamate in children with autism spectrum disorders R Tirouvanziam, TV Obukhanych, J Laval, PA Aronov, R Libove, ... Journal of autism and developmental disorders 42, 827-836, 2012 | 78 | 2012 |
Basophil CD203c levels are increased at baseline and can be used to monitor omalizumab treatment in subjects with nut allergy Y Gernez, R Tirouvanziam, G Yu, EEB Ghosn, N Reshamwala, T Nguyen, ... International archives of allergy and immunology 154 (4), 318-327, 2011 | 78 | 2011 |