Genes mirror geography within Europe J Novembre, T Johnson, K Bryc, Z Kutalik, AR Boyko, A Auton, A Indap, ... Nature 456 (7218), 98-101, 2008 | 1838 | 2008 |
The support of human genetic evidence for approved drug indications MR Nelson, H Tipney, JL Painter, J Shen, P Nicoletti, Y Shen, A Floratos, ... Nature genetics 47 (8), 856-860, 2015 | 1380 | 2015 |
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin AK Daly, PT Donaldson, P Bhatnagar, Y Shen, I Pe'er, A Floratos, MJ Daly, ... Nature genetics 41 (7), 816-819, 2009 | 1185 | 2009 |
Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry M Ehrich, MR Nelson, P Stanssens, M Zabeau, T Liloglou, G Xinarianos, ... Proceedings of the National Academy of Sciences 102 (44), 15785-15790, 2005 | 974 | 2005 |
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people MR Nelson, D Wegmann, MG Ehm, D Kessner, P St. Jean, C Verzilli, ... Science 337 (6090), 100-104, 2012 | 810 | 2012 |
Correlation between genetic and geographic structure in Europe O Lao, TT Lu, M Nothnagel, O Junge, S Freitag-Wolf, A Caliebe, ... Current Biology 18 (16), 1241-1248, 2008 | 616 | 2008 |
Genome-wide patterns of population structure and admixture in West Africans and African Americans K Bryc, A Auton, MR Nelson, JR Oksenberg, SL Hauser, S Williams, ... Proceedings of the National Academy of Sciences 107 (2), 786-791, 2010 | 537 | 2010 |
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles MI Lucena, M Molokhia, Y Shen, TJ Urban, GP Aithal, RJ Andrade, ... Gastroenterology 141 (1), 338-347, 2011 | 506 | 2011 |
A combinatorial partitioning method to identify multilocus genotypic partitions that predict quantitative trait variation MR Nelson, SLR Kardia, RE Ferrell, CF Sing Genome research 11 (3), 458-470, 2001 | 479 | 2001 |
HIBAG—HLA genotype imputation with attribute bagging X Zheng, J Shen, C Cox, JC Wakefield, MG Ehm, MR Nelson, BS Weir The pharmacogenomics journal 14 (2), 192-200, 2014 | 443 | 2014 |
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases J Zheng, V Haberland, D Baird, V Walker, PC Haycock, MR Hurle, ... Nature genetics 52 (10), 1122-1131, 2020 | 422 | 2020 |
Exome sequencing and characterization of 49,960 individuals in the UK Biobank CV Van Hout, I Tachmazidou, JD Backman, JD Hoffman, D Liu, ... Nature 586 (7831), 749-756, 2020 | 418 | 2020 |
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research MR Nelson, K Bryc, KS King, A Indap, AR Boyko, J Novembre, LP Briley, ... The American Journal of Human Genetics 83 (3), 347-358, 2008 | 305 | 2008 |
Improved genome inference in the MHC using a population reference graph A Dilthey, C Cox, Z Iqbal, MR Nelson, G McVean Nature genetics 47 (6), 682-688, 2015 | 235 | 2015 |
Association of liver injury from specific drugs, or groups of drugs, with polymorphisms in HLA and other genes in a genome-wide association study P Nicoletti, GP Aithal, ES Bjornsson, RJ Andrade, A Sawle, M Arrese, ... Gastroenterology 152 (5), 1078-1089, 2017 | 227 | 2017 |
Identification of the semaphorin receptor PLXNA2 as a candidate for susceptibility to schizophrenia S Mah, MR Nelson, LE Delisi, RH Reneland, N Markward, MR James, ... Molecular psychiatry 11 (5), 471-478, 2006 | 215 | 2006 |
Global distribution of genomic diversity underscores rich complex history of continental human populations A Auton, K Bryc, AR Boyko, KE Lohmueller, J Novembre, A Reynolds, ... Genome research 19 (5), 795-803, 2009 | 214 | 2009 |
GWASdb v2: an update database for human genetic variants identified by genome-wide association studies MJ Li, Z Liu, P Wang, MP Wong, MR Nelson, JPA Kocher, M Yeager, ... Nucleic acids research 44 (D1), D869-D876, 2016 | 207 | 2016 |
Multi-population classical HLA type imputation A Dilthey, S Leslie, L Moutsianas, J Shen, C Cox, MR Nelson, G McVean PLoS computational biology 9 (2), e1002877, 2013 | 206 | 2013 |
Quantitative DNA methylation predicts survival in adult acute myeloid leukemia L Bullinger, M Ehrich, K Döhner, RF Schlenk, H Döhner, MR Nelson, ... Blood, The Journal of the American Society of Hematology 115 (3), 636-642, 2010 | 189 | 2010 |