关注
Alaa A.-M. Abdel-Aziz PhD
Alaa A.-M. Abdel-Aziz PhD
King Saud University, Mansoura University, Kumamoto University
在 ksu.edu.sa 的电子邮件经过验证
标题
引用次数
引用次数
年份
Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: molecular docking study
AS El-Azab, MA Al-Omar, AM Alaa, NI Abdel-Aziz, AA Magda, AM Aleisa, ...
European journal of medicinal chemistry 45 (9), 4188-4198, 2010
2892010
Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4 (3H)-quinazolinone analogs
ST Al-Rashood, IA Aboldahab, MN Nagi, LA Abouzeid, AAM Abdel-Aziz, ...
Bioorganic & medicinal chemistry 14 (24), 8608-8621, 2006
2442006
Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4 (3H)-quinazolinone analogs
AM Al-Obaid, SG Abdel-Hamide, HA El-Kashef, AM Alaa, AS El-Azab, ...
European journal of medicinal chemistry 44 (6), 2379-2391, 2009
2292009
Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study
AM Alaa
European journal of medicinal chemistry 42 (5), 614-626, 2007
1942007
Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study
AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, YA Asiri, KEH ElTahir
Bioorganic & medicinal chemistry 19 (11), 3416-3424, 2011
1832011
Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2
AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, KEH ElTahir
Bioorganic & medicinal chemistry 20 (10), 3306-3316, 2012
1722012
Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2, 6-substituted-quinazolin-4-ones
FAM Al-Omary, LA Abou-Zeid, MN Nagi, ESE Habib, AM Alaa, AS El-Azab, ...
Bioorganic & medicinal chemistry 18 (8), 2849-2863, 2010
1602010
Synthesis, antimicrobial activity and conformational analysis of novel substituted pyridines: BF3-promoted reaction of hydrazine with 2-alkoxy pyridines
FE Goda, AM Alaa, OA Attef
Bioorganic & medicinal chemistry 12 (8), 1845-1852, 2004
1542004
Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: anti-inflammatory and analgesic activities
AM Alanazi, AS El-Azab, IA Al-Suwaidan, KEH ElTahir, YA Asiri, ...
European journal of medicinal chemistry 92, 115-123, 2015
1312015
Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study
AM Alaa, KEH ElTahir, YA Asiri
European journal of medicinal chemistry 46 (5), 1648-1655, 2011
1212011
Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4 (3H)-quinazolinones
AM Alaa, LA Abou-Zeid, KEH ElTahir, RR Ayyad, AA Magda, AS El-Azab
European Journal of Medicinal Chemistry 121, 410-421, 2016
1052016
Synthesis, antimicrobial activity and molecular modeling of cobalt and nickel complexes containing the bulky ligand: bis [N-(2, 6-diisopropylphenyl) imino] acenaphthene
U El-Ayaan, AM Alaa
European Journal of Medicinal Chemistry 40 (12), 1214-1221, 2005
962005
Synthesis and antitumor evaluation of trimethoxyanilides based on 4 (3H)-quinazolinone scaffolds
MA Mohamed, RR Ayyad, TZ Shawer, AM Alaa, AS El-Azab
European journal of medicinal chemistry 112, 106-113, 2016
932016
Oral colon targeted delivery systems for treatment of inflammatory bowel diseases: synthesis, in vitro and in vivo assessment
AH El-Kamel, AM Alaa, AJ Fatani, HI El-Subbagh
International journal of pharmaceutics 358 (1-2), 248-255, 2008
882008
Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibition activities and molecular docking study of pyrazoline derivatives
MA Abdel-Sayed, SM Bayomi, MA El-Sherbeny, NI Abdel-Aziz, ...
Bioorganic & Medicinal Chemistry 24 (9), 2032-2042, 2016
832016
Lewis acid-promoted transformation of 2-alkoxypyridines into 2-aminopyridines and their antibacterial activity. Part 2: Remarkably facile C–N bond formation
AM Alaa, HI El-Subbagh, T Kunieda
Bioorganic & medicinal chemistry 13 (16), 4929-4935, 2005
832005
Design, synthesis of 2, 3-disubstitued 4 (3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies
AM Alaa, LA Abou-Zeid, KEH ElTahir, MA Mohamed, MAA El-Enin, ...
Bioorganic & Medicinal Chemistry 24 (16), 3818-3828, 2016
822016
Synthesis, antitumor activity and molecular docking study of some novel 3-benzyl-4 (3H) quinazolinone analogues
IA Al-Suwaidan, AAM Abdel-Aziz, TZ Shawer, RR Ayyad, AM Alanazi, ...
Journal of enzyme inhibition and medicinal chemistry 31 (1), 78-89, 2016
802016
Design, synthesis and antibacterial activity of fluoroquinolones containing bulky arenesulfonyl fragment: 2D-QSAR and docking study
AM Alaa, YA Asiri, MHM Al-Agamy
European journal of medicinal chemistry 46 (11), 5487-5497, 2011
792011
Synthesis and antitumor evaluation of novel cyclic arylsulfonylureas: ADME-T and pharmacophore prediction
IM El-Deeb, SM Bayoumi, MA El-Sherbeny, AM Alaa
European journal of medicinal chemistry 45 (6), 2516-2530, 2010
782010
系统目前无法执行此操作,请稍后再试。
文章 1–20