Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: molecular docking study AS El-Azab, MA Al-Omar, AM Alaa, NI Abdel-Aziz, AA Magda, AM Aleisa, ... European journal of medicinal chemistry 45 (9), 4188-4198, 2010 | 289 | 2010 |
Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4 (3H)-quinazolinone analogs ST Al-Rashood, IA Aboldahab, MN Nagi, LA Abouzeid, AAM Abdel-Aziz, ... Bioorganic & medicinal chemistry 14 (24), 8608-8621, 2006 | 244 | 2006 |
Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4 (3H)-quinazolinone analogs AM Al-Obaid, SG Abdel-Hamide, HA El-Kashef, AM Alaa, AS El-Azab, ... European journal of medicinal chemistry 44 (6), 2379-2391, 2009 | 229 | 2009 |
Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study AM Alaa European journal of medicinal chemistry 42 (5), 614-626, 2007 | 194 | 2007 |
Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, YA Asiri, KEH ElTahir Bioorganic & medicinal chemistry 19 (11), 3416-3424, 2011 | 183 | 2011 |
Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2 AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, KEH ElTahir Bioorganic & medicinal chemistry 20 (10), 3306-3316, 2012 | 172 | 2012 |
Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2, 6-substituted-quinazolin-4-ones FAM Al-Omary, LA Abou-Zeid, MN Nagi, ESE Habib, AM Alaa, AS El-Azab, ... Bioorganic & medicinal chemistry 18 (8), 2849-2863, 2010 | 160 | 2010 |
Synthesis, antimicrobial activity and conformational analysis of novel substituted pyridines: BF3-promoted reaction of hydrazine with 2-alkoxy pyridines FE Goda, AM Alaa, OA Attef Bioorganic & medicinal chemistry 12 (8), 1845-1852, 2004 | 154 | 2004 |
Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: anti-inflammatory and analgesic activities AM Alanazi, AS El-Azab, IA Al-Suwaidan, KEH ElTahir, YA Asiri, ... European journal of medicinal chemistry 92, 115-123, 2015 | 131 | 2015 |
Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study AM Alaa, KEH ElTahir, YA Asiri European journal of medicinal chemistry 46 (5), 1648-1655, 2011 | 121 | 2011 |
Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4 (3H)-quinazolinones AM Alaa, LA Abou-Zeid, KEH ElTahir, RR Ayyad, AA Magda, AS El-Azab European Journal of Medicinal Chemistry 121, 410-421, 2016 | 105 | 2016 |
Synthesis, antimicrobial activity and molecular modeling of cobalt and nickel complexes containing the bulky ligand: bis [N-(2, 6-diisopropylphenyl) imino] acenaphthene U El-Ayaan, AM Alaa European Journal of Medicinal Chemistry 40 (12), 1214-1221, 2005 | 96 | 2005 |
Synthesis and antitumor evaluation of trimethoxyanilides based on 4 (3H)-quinazolinone scaffolds MA Mohamed, RR Ayyad, TZ Shawer, AM Alaa, AS El-Azab European journal of medicinal chemistry 112, 106-113, 2016 | 93 | 2016 |
Oral colon targeted delivery systems for treatment of inflammatory bowel diseases: synthesis, in vitro and in vivo assessment AH El-Kamel, AM Alaa, AJ Fatani, HI El-Subbagh International journal of pharmaceutics 358 (1-2), 248-255, 2008 | 88 | 2008 |
Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibition activities and molecular docking study of pyrazoline derivatives MA Abdel-Sayed, SM Bayomi, MA El-Sherbeny, NI Abdel-Aziz, ... Bioorganic & Medicinal Chemistry 24 (9), 2032-2042, 2016 | 83 | 2016 |
Lewis acid-promoted transformation of 2-alkoxypyridines into 2-aminopyridines and their antibacterial activity. Part 2: Remarkably facile C–N bond formation AM Alaa, HI El-Subbagh, T Kunieda Bioorganic & medicinal chemistry 13 (16), 4929-4935, 2005 | 83 | 2005 |
Design, synthesis of 2, 3-disubstitued 4 (3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies AM Alaa, LA Abou-Zeid, KEH ElTahir, MA Mohamed, MAA El-Enin, ... Bioorganic & Medicinal Chemistry 24 (16), 3818-3828, 2016 | 82 | 2016 |
Synthesis, antitumor activity and molecular docking study of some novel 3-benzyl-4 (3H) quinazolinone analogues IA Al-Suwaidan, AAM Abdel-Aziz, TZ Shawer, RR Ayyad, AM Alanazi, ... Journal of enzyme inhibition and medicinal chemistry 31 (1), 78-89, 2016 | 80 | 2016 |
Design, synthesis and antibacterial activity of fluoroquinolones containing bulky arenesulfonyl fragment: 2D-QSAR and docking study AM Alaa, YA Asiri, MHM Al-Agamy European journal of medicinal chemistry 46 (11), 5487-5497, 2011 | 79 | 2011 |
Synthesis and antitumor evaluation of novel cyclic arylsulfonylureas: ADME-T and pharmacophore prediction IM El-Deeb, SM Bayoumi, MA El-Sherbeny, AM Alaa European journal of medicinal chemistry 45 (6), 2516-2530, 2010 | 78 | 2010 |