Distinct tau prion strains propagate in cells and mice and define different tauopathies DW Sanders, SK Kaufman, SL DeVos, AM Sharma, H Mirbaha, A Li, ... Neuron 82 (6), 1271-1288, 2014 | 1023 | 2014 |
Neuronal activity enhances tau propagation and tau pathology in vivo JW Wu, SA Hussaini, IM Bastille, GA Rodriguez, A Mrejeru, K Rilett, ... Nature neuroscience 19 (8), 1085-1092, 2016 | 720 | 2016 |
Competing protein-RNA interaction networks control multiphase intracellular organization DW Sanders, N Kedersha, DSW Lee, AR Strom, V Drake, JA Riback, ... Cell 181 (2), 306-324. e28, 2020 | 605 | 2020 |
Liquid nuclear condensates mechanically sense and restructure the genome Y Shin, YC Chang, DSW Lee, J Berry, DW Sanders, P Ronceray, ... Cell 175 (6), 1481-1491. e13, 2018 | 592 | 2018 |
Composition-dependent thermodynamics of intracellular phase separation JA Riback, L Zhu, MC Ferrolino, M Tolbert, DM Mitrea, DW Sanders, ... Nature 581 (7807), 209-214, 2020 | 505 | 2020 |
Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo SK Kaufman, DW Sanders, TL Thomas, AJ Ruchinskas, J Vaquer-Alicea, ... Neuron 92 (4), 796-812, 2016 | 422 | 2016 |
Propagation of prions causing synucleinopathies in cultured cells AL Woerman, J Stöhr, A Aoyagi, R Rampersaud, Z Krejciova, JC Watts, ... Proceedings of the National Academy of Sciences 112 (35), E4949-E4958, 2015 | 250 | 2015 |
Tau trimers are the minimal propagation unit spontaneously internalized to seed intracellular aggregation H Mirbaha, BB Holmes, DW Sanders, J Bieschke, MI Diamond Journal of Biological Chemistry 290 (24), 14893-14903, 2015 | 241 | 2015 |
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation DW Sanders, CC Jumper, PJ Ackerman, D Bracha, A Donlic, H Kim, ... Elife 10, e65962, 2021 | 188 | 2021 |
Nucleation landscape of biomolecular condensates SF Shimobayashi, P Ronceray, DW Sanders, MP Haataja, ... Nature 599 (7885), 503-506, 2021 | 137 | 2021 |
Prions and protein assemblies that convey biological information in health and disease (REVIEW) DW Sanders, SK Kaufman, BB Holmes, MI Diamond Neuron 89 (3), 433-448, 2016 | 90 | 2016 |
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system I Saha, P Yuste-Checa, M Da Silva Padilha, Q Guo, R Körner, ... Nature Communications 14 (1), 560, 2023 | 38* | 2023 |
Size distributions of intracellular condensates reflect competition between coalescence and nucleation DSW Lee, CH Choi, DW Sanders, L Beckers, JA Riback, CP Brangwynne, ... Nature Physics 19 (4), 586-596, 2023 | 34 | 2023 |
The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition G Eskandari-Sedighi, N Daude, H Gapeshina, DW Sanders, ... Molecular neurodegeneration 12 (1), 72, 2017 | 17 | 2017 |
Neurodegenerative disease: RNA repeats put a freeze on cells (COMMENTARY) DW Sanders, CP Brangwynne Nature 546 (7657), 215-216, 2017 | 13 | 2017 |
Poly (GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions J Park, Y Wu, W Shao, TF Gendron, SJF van der Spek, G Sultanakhmetov, ... Cell Reports 42 (8), 2023 | 11 | 2023 |
Condensate interfaces can accelerate protein aggregation CH Choi, DSW Lee, DW Sanders, CP Brangwynne Biophysical journal 123 (11), 1404-1413, 2024 | 8 | 2024 |
DnaJC7 specifically regulates tau seeding VA Perez, DW Sanders, A Mendoza-Oliva, BE Stopschinski, V Mullapudi, ... Elife 12, e86936, 2023 | 8 | 2023 |
Spatially constrained transcriptional sources drive asphericity of intracellular liquids JA Riback, DSW Lee, JM Eeftens, DW Sanders, L Beckers, ... Biophysical Journal 120 (3), 278a, 2021 | 2 | 2021 |
Synthetic peptides for dissolving tau inclusions CP Brangwynne, DW Sanders US Patent App. 18/124,252, 2023 | | 2023 |