Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice VW Dolinsky, S Chakrabarti, TJ Pereira, T Oka, J Levasseur, D Beker, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (10 …, 2013 | 218 | 2013 |
Empagliflozin blunts worsening cardiac dysfunction associated with reduced NLRP3 (nucleotide-binding domain-like receptor protein 3) inflammasome activation in heart failure NJ Byrne, N Matsumura, ZH Maayah, M Ferdaoussi, S Takahara, ... Circulation: Heart Failure 13 (1), e006277, 2020 | 185 | 2020 |
Empagliflozin prevents worsening of cardiac function in an experimental model of pressure overload-induced heart failure NJ Byrne, N Parajuli, JL Levasseur, J Boisvenue, DL Beker, G Masson, ... Basic to Translational Science 2 (4), 347-354, 2017 | 176 | 2017 |
Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency KL Ho, L Zhang, C Wagg, R Al Batran, K Gopal, J Levasseur, T Leone, ... Cardiovascular research 115 (11), 1606-1616, 2019 | 156 | 2019 |
Resveratrol treatment of mice with pressure-overload–induced heart failure improves diastolic function and cardiac energy metabolism MM Sung, SK Das, J Levasseur, NJ Byrne, D Fung, TT Kim, G Masson, ... Circulation: Heart Failure 8 (1), 128-137, 2015 | 101 | 2015 |
Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction N Fillmore, JL Levasseur, A Fukushima, CS Wagg, W Wang, JRB Dyck, ... Molecular medicine 24, 1-12, 2018 | 100 | 2018 |
Resveratrol improves exercise performance and skeletal muscle oxidative capacity in heart failure MM Sung, NJ Byrne, IM Robertson, TT Kim, V Samokhvalov, J Levasseur, ... American Journal of Physiology-Heart and Circulatory Physiology 312 (4 …, 2017 | 88 | 2017 |
Fecal transplant from resveratrol-fed donors improves glycaemia and cardiovascular features of the metabolic syndrome in mice TT Kim, N Parajuli, MM Sung, SC Bairwa, J Levasseur, CLM Soltys, ... American Journal of Physiology-Endocrinology and Metabolism 315 (4), E511-E519, 2018 | 79 | 2018 |
Angiotensin‐converting enzyme 2 antagonizes angiotensin II‐induced pressor response and NADPH oxidase activation in Wistar–Kyoto rats and spontaneously hypertensive rats J Lo, VB Patel, Z Wang, J Levasseur, S Kaufman, JM Penninger, GY Oudit Experimental physiology 98 (1), 109-122, 2013 | 79 | 2013 |
Chronically elevating circulating ketones can reduce cardiac inflammation and blunt the development of heart failure NJ Byrne, S Soni, S Takahara, M Ferdaoussi, R Al Batran, AM Darwesh, ... Circulation: Heart Failure 13 (6), e006573, 2020 | 78 | 2020 |
Cardiomyocyte-specific ablation of CD36 accelerates the progression from compensated cardiac hypertrophy to heart failure MM Sung, NJ Byrne, TT Kim, J Levasseur, G Masson, JJ Boisvenue, ... American Journal of Physiology-Heart and Circulatory Physiology 312 (3 …, 2017 | 54 | 2017 |
Characterisation of the selective reduced uteroplacental perfusion (sRUPP) model of preeclampsia JS Morton, J Levasseur, E Ganguly, A Quon, R Kirschenman, JRB Dyck, ... Scientific reports 9 (1), 9565, 2019 | 50 | 2019 |
Effect of portal hypertension on splenic blood flow, intrasplenic extravasation and systemic blood pressure S Kaufman, J Levasseur American Journal of Physiology-Regulatory, Integrative and Comparative …, 2003 | 47 | 2003 |
Normalization of cardiac substrate utilization and left ventricular hypertrophy precede functional recovery in heart failure regression NJ Byrne, J Levasseur, MM Sung, G Masson, J Boisvenue, ME Young, ... Cardiovascular research 110 (2), 249-257, 2016 | 39 | 2016 |
2-Methoxyestradiol protects against pressure overload-induced left ventricular hypertrophy ZH Maayah, J Levasseur, R Siva Piragasam, G Abdelhamid, JRB Dyck, ... Scientific reports 8 (1), 2780, 2018 | 36 | 2018 |
Chronic exogenous ketone supplementation blunts the decline of cardiac function in the failing heart S Takahara, S Soni, K Phaterpekar, TT Kim, ZH Maayah, JL Levasseur, ... ESC Heart Failure 8 (6), 5606-5612, 2021 | 22 | 2021 |
Intrauterine exposure to chronic hypoxia in the rat leads to progressive diastolic function and increased aortic stiffness from early postnatal developmental stages P Kumar, JS Morton, A Shah, V Do, C Sergi, J Serrano‐Lomelin, ... Physiological Reports 8 (1), e14327, 2020 | 11 | 2020 |
Ameliorative role of fluconazole against abdominal aortic constriction–induced cardiac hypertrophy in rats SM Shoieb, AH Alammari, J Levasseur, H Silver, JRB Dyck, AOS El-Kadi Journal of cardiovascular pharmacology 79 (6), 833-845, 2022 | 8 | 2022 |
Ketones provide an extra source of fuel for the failing heart without impairing glucose oxidation S Pherwani, D Connolly, Q Sun, QG Karwi, M Carr, KL Ho, CS Wagg, ... Metabolism 154, 155818, 2024 | 2 | 2024 |
Cardiomyocyte‐Specific Ablation of the Long‐Chain Fatty Acid Transporter CD36 Accelerates the Progression of Pressure Overload‐Induced Heart Failure in Mice M Sung, N Byrne, J Levasseur, G Masson, M Febbraio, J Dyck The FASEB Journal 29, LB593, 2015 | 1 | 2015 |