Vertex models of epithelial morphogenesis AG Fletcher, M Osterfield, RE Baker, SY Shvartsman Biophysical journal 106 (11), 2291-2304, 2014 | 601 | 2014 |
Chaste: an open source C++ library for computational physiology and biology GR Mirams, CJ Arthurs, MO Bernabeu, R Bordas, J Cooper, A Corrias, ... PLoS computational biology 9 (3), e1002970, 2013 | 500 | 2013 |
Chaste: a test-driven approach to software development for biological modelling J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ... Computer Physics Communications 180 (12), 2452-2471, 2009 | 304 | 2009 |
Quantification of crypt and stem cell evolution in the normal and neoplastic human colon AM Baker, B Cereser, S Melton, AG Fletcher, M Rodriguez-Justo, ... Cell reports 8 (4), 940-947, 2014 | 234 | 2014 |
Comparing individual-based approaches to modelling the self-organization of multicellular tissues JM Osborne, AG Fletcher, JM Pitt-Francis, PK Maini, DJ Gavaghan PLoS computational biology 13 (2), e1005387, 2017 | 224 | 2017 |
An integrative computational model for intestinal tissue renewal IMM Van Leeuwen, GR Mirams, A Walter, A Fletcher, P Murray, J Osborne, ... Cell proliferation 42 (5), 617-636, 2009 | 183 | 2009 |
Implementing vertex dynamics models of cell populations in biology within a consistent computational framework AG Fletcher, JM Osborne, PK Maini, DJ Gavaghan Progress in biophysics and molecular biology 113 (2), 299-326, 2013 | 175 | 2013 |
Steering evolution with sequential therapy to prevent the emergence of bacterial antibiotic resistance D Nichol, P Jeavons, AG Fletcher, RA Bonomo, PK Maini, JL Paul, ... PLoS computational biology 11 (9), e1004493, 2015 | 168 | 2015 |
A hybrid approach to multi-scale modelling of cancer JM Osborne, A Walter, SK Kershaw, GR Mirams, AG Fletcher, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2010 | 151 | 2010 |
A computational study of discrete mechanical tissue models P Pathmanathan, J Cooper, A Fletcher, G Mirams, P Murray, J Osborne, ... Physical biology 6 (3), 036001, 2009 | 147 | 2009 |
A PHABULOSA/cytokinin feedback loop controls root growth in Arabidopsis RD Ioio, C Galinha, AG Fletcher, SP Grigg, A Molnar, V Willemsen, ... Current Biology 22 (18), 1699-1704, 2012 | 145 | 2012 |
Mechanisms and mechanics of cell competition in epithelia JP Vincent, AG Fletcher, LAL Baena-Lopez Nature reviews Molecular cell biology 14 (9), 581-591, 2013 | 144 | 2013 |
Migration and horizontal gene transfer divide microbial genomes into multiple niches R Niehus, S Mitri, AG Fletcher, KR Foster Nature communications 6 (1), 8924, 2015 | 140 | 2015 |
Unipolar distributions of junctional Myosin II identify cell stripe boundaries that drive cell intercalation throughout Drosophila axis extension RJ Tetley, GB Blanchard, AG Fletcher, RJ Adams, B Sanson Elife 5, e12094, 2016 | 111 | 2016 |
Mechanocellular models of epithelial morphogenesis AG Fletcher, F Cooper, RE Baker Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017 | 106 | 2017 |
Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi A Parker, OJ Maclaren, AG Fletcher, D Muraro, PA Kreuzaler, HM Byrne, ... The FASEB Journal 31 (2), 636, 2017 | 95 | 2017 |
Morphological plant modeling: unleashing geometric and topological potential within the plant sciences A Bucksch, A Atta-Boateng, AF Azihou, D Battogtokh, A Baumgartner, ... Frontiers in plant science 8, 900, 2017 | 82 | 2017 |
Oxygen consumption dynamics in steady-state tumour models DR Grimes, AG Fletcher, M Partridge Royal Society open science 1 (1), 140080, 2014 | 81 | 2014 |
Elevated apoptosis impairs epithelial cell turnover and shortens villi in TNF-driven intestinal inflammation A Parker, L Vaux, AM Patterson, A Modasia, D Muraro, AG Fletcher, ... Cell death & disease 10 (2), 108, 2019 | 77 | 2019 |
Mathematical modeling of monoclonal conversion in the colonic crypt AG Fletcher, CJW Breward, SJ Chapman Journal of theoretical biology 300, 118-133, 2012 | 77 | 2012 |