Nanomaterial Delivery Systems for mRNA Vaccines MGADW Michael D. Buschmann 1, *, Manuel J. Carrasco 1, Suman Alishetty 1 ... Vaccines 9 (65), 2021 | 423 | 2021 |
D614G spike mutation increases SARS CoV-2 susceptibility to neutralization D Weissman, MG Alameh, T de Silva, P Collini, H Hornsby, R Brown, ... Cell host & microbe 29 (1), 23-31. e4, 2021 | 365 | 2021 |
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses MG Alameh, I Tombácz, E Bettini, K Lederer, S Ndeupen, C Sittplangkoon, ... Immunity 54 (12), 2877-2892. e7, 2021 | 349 | 2021 |
An ionizable lipid toolbox for RNA delivery X Han, H Zhang, K Butowska, KL Swingle, MG Alameh, D Weissman, ... Nature communications 12 (1), 7233, 2021 | 259 | 2021 |
Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination J Tang, C Zeng, TM Cox, C Li, YM Son, IS Cheon, Y Wu, S Behl, JJ Taylor, ... Science immunology 7 (76), eadd4853, 2022 | 211 | 2022 |
Ionization and structural properties of mRNA lipid nanoparticles influence expression in intramuscular and intravascular administration MJ Carrasco, S Alishetty, MG Alameh, H Said, L Wright, M Paige, ... Communications biology 4 (1), 956, 2021 | 203 | 2021 |
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes CP Arevalo, MJ Bolton, V Le Sage, N Ye, C Furey, H Muramatsu, ... Science 378 (6622), 899-904, 2022 | 158 | 2022 |
Scalable mRNA and siRNA lipid nanoparticle production using a parallelized microfluidic device SJ Shepherd, CC Warzecha, S Yadavali, R El-Mayta, MG Alameh, ... Nano letters 21 (13), 5671-5680, 2021 | 155 | 2021 |
Ionizable lipid nanoparticles for in utero mRNA delivery RS Riley, MV Kashyap, MM Billingsley, B White, MG Alameh, SK Bose, ... Science advances 7 (3), eaba1028, 2021 | 132 | 2021 |
siRNA delivery with chitosan: influence of chitosan molecular weight, degree of deacetylation, and amine to phosphate ratio on in vitro silencing efficiency, hemocompatibility … M Alameh, M Lavertu, N Tran-Khanh, CY Chang, F Lesage, M Bail, ... Biomacromolecules 19 (1), 112-131, 2018 | 122 | 2018 |
Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs I Tombácz, D Laczkó, H Shahnawaz, H Muramatsu, A Natesan, ... Molecular Therapy 29 (11), 3293-3304, 2021 | 120 | 2021 |
Low molecular weight chitosan nanoparticulate system at low N: P ratio for nontoxic polynucleotide delivery M Alameh, D DeJesus, M Jean, V Darras, M Thibault, M Lavertu, ... International journal of nanomedicine, 1399-1414, 2012 | 107 | 2012 |
Vaccine technologies and platforms for infectious diseases: Current progress, challenges, and opportunities M Ghattas, G Dwivedi, M Lavertu, MG Alameh Vaccines 9 (12), 1490, 2021 | 91 | 2021 |
Chitosan-based therapeutic nanoparticles for combination gene therapy and gene silencing of in vitro cell lines relevant to type 2 diabetes M Jean, M Alameh, D De Jesus, M Thibault, M Lavertu, V Darras, M Nelea, ... European Journal of Pharmaceutical Sciences 45 (1-2), 138-149, 2012 | 91 | 2012 |
Messenger RNA-Based Vaccines Against Infectious Diseases MG Alameh, D Weissman, N Pardi Springer, Berlin, Heidelberg, 2020 | 83 | 2020 |
Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models RL Hajnik, JA Plante, Y Liang, MG Alameh, J Tang, SR Bonam, C Zhong, ... Science translational medicine 14 (662), eabq1945, 2022 | 73 | 2022 |
Effective and safe gene-based delivery of GLP-1 using chitosan/plasmid-DNA therapeutic nanocomplexes in an animal model of type 2 diabetes M Jean, M Alameh, MD Buschmann, A Merzouki Gene therapy 18 (8), 807-816, 2011 | 70 | 2011 |
Rational design of bisphosphonate lipid-like materials for mRNA delivery to the bone microenvironment L Xue, N Gong, SJ Shepherd, X Xiong, X Liao, X Han, G Zhao, C Song, ... Journal of the American Chemical Society 144 (22), 9926-9937, 2022 | 68 | 2022 |
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer JR Melamed, SS Yerneni, ML Arral, ST LoPresti, N Chaudhary, ... Science Advances 9 (4), eade1444, 2023 | 60 | 2023 |
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy KL Swingle, HC Safford, HC Geisler, AG Hamilton, AS Thatte, ... Journal of the American Chemical Society 145 (8), 4691-4706, 2023 | 59 | 2023 |