CSF-1R inhibition alters macrophage polarization and blocks glioma progression SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ... Nature medicine 19 (10), 1264-1272, 2013 | 2219 | 2013 |
Human iPSC-based modeling of late-onset disease via progerin-induced aging JD Miller, YM Ganat, S Kishinevsky, RL Bowman, B Liu, EY Tu, ... Cell stem cell 13 (6), 691-705, 2013 | 799 | 2013 |
GlioVis data portal for visualization and analysis of brain tumor expression datasets RL Bowman, Q Wang, A Carro, RGW Verhaak, M Squatrito Neuro-oncology 19 (1), 139-141, 2017 | 680 | 2017 |
Interrogation of the microenvironmental landscape in brain tumors reveals disease-specific alterations of immune cells F Klemm, RR Maas, RL Bowman, M Kornete, K Soukup, S Nassiri, ... Cell 181 (7), 1643-1660. e17, 2020 | 664 | 2020 |
The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas DF Quail, RL Bowman, L Akkari, ML Quick, AJ Schuhmacher, JT Huse, ... Science 352 (6288), aad3018, 2016 | 596 | 2016 |
Macrophage ontogeny underlies differences in tumor-specific education in brain malignancies RL Bowman, F Klemm, L Akkari, SM Pyonteck, L Sevenich, DF Quail, ... Cell reports 17 (9), 2445-2459, 2016 | 549 | 2016 |
Clonal hematopoiesis and evolution to hematopoietic malignancies RL Bowman, L Busque, RL Levine Cell stem cell 22 (2), 157-170, 2018 | 446 | 2018 |
Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S L Sevenich, RL Bowman, SD Mason, DF Quail, F Rapaport, BT Elie, ... Nature cell biology 16 (9), 876-888, 2014 | 381 | 2014 |
Single-cell mutation analysis of clonal evolution in myeloid malignancies LA Miles, RL Bowman, TR Merlinsky, IS Csete, AT Ooi, ... Nature 587 (7834), 477-482, 2020 | 364 | 2020 |
Adipocyte-derived lipids mediate melanoma progression via FATP proteins M Zhang, JS Di Martino, RL Bowman, NR Campbell, SC Baksh, ... Cancer discovery 8 (8), 1006-1025, 2018 | 281 | 2018 |
Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance L Akkari, RL Bowman, J Tessier, F Klemm, SM Handgraaf, M de Groot, ... Science translational medicine 12 (552), eaaw7843, 2020 | 216 | 2020 |
Self-renewal of CD133hi cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer P Sansone, C Ceccarelli, M Berishaj, Q Chang, VK Rajasekhar, F Perna, ... Nature communications 7 (1), 10442, 2016 | 170 | 2016 |
STAT3 and STAT6 signaling pathways synergize to promote cathepsin secretion from macrophages via IRE1α activation D Yan, HW Wang, RL Bowman, JA Joyce Cell reports 16 (11), 2914-2927, 2016 | 159 | 2016 |
Microenvironment-derived factors driving metastatic plasticity in melanoma IS Kim, S Heilmann, ER Kansler, Y Zhang, M Zimmer, K Ratnakumar, ... Nature communications 8 (1), 14343, 2017 | 143 | 2017 |
Evolution of cancer stem-like cells in endocrine-resistant metastatic breast cancers is mediated by stromal microvesicles P Sansone, M Berishaj, VK Rajasekhar, C Ceccarelli, Q Chang, ... Cancer research 77 (8), 1927-1941, 2017 | 130 | 2017 |
Cohesin members Stag1 and Stag2 display distinct roles in chromatin accessibility and topological control of HSC self-renewal and differentiation AD Viny, RL Bowman, Y Liu, VP Lavallée, SE Eisman, W Xiao, ... Cell stem cell 25 (5), 682-696. e8, 2019 | 116 | 2019 |
Epigenetic identity in AML depends on disruption of nonpromoter regulatory elements and is affected by antagonistic effects of mutations in epigenetic modifiers JL Glass, D Hassane, BJ Wouters, H Kunimoto, R Avellino, ... Cancer discovery 7 (8), 868-883, 2017 | 116 | 2017 |
Microglia promote glioblastoma via mTOR‐mediated immunosuppression of the tumour microenvironment AA Dumas, N Pomella, G Rosser, L Guglielmi, C Vinel, TO Millner, J Rees, ... The EMBO journal 39 (15), e103790, 2020 | 105 | 2020 |
TET2 in normal and malignant hematopoiesis RL Bowman, RL Levine Cold Spring Harbor perspectives in medicine 7 (8), a026518, 2017 | 89 | 2017 |
Underlying causes and therapeutic targeting of the inflammatory tumor microenvironment EA Comen, RL Bowman, M Kleppe Frontiers in cell and developmental biology 6, 56, 2018 | 77 | 2018 |