The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling X Su, DH Floyd, A Hughes, J Xiang, JG Schneider, O Uluckan, E Heller, ... The Journal of clinical investigation 122 (10), 3579-3592, 2012 | 103 | 2012 |
Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment E Heller, MA Hurchla, J Xiang, X Su, S Chen, J Schneider, KS Joeng, ... Cancer research 72 (4), 897-907, 2012 | 87 | 2012 |
Antagonizing integrin β3 increases immunosuppression in cancer X Su, AK Esser, SR Amend, J Xiang, Y Xu, MH Ross, GC Fox, ... Cancer research 76 (12), 3484-3495, 2016 | 77 | 2016 |
CXCR4 protein epitope mimetic antagonist POL5551 disrupts metastasis and enhances chemotherapy effect in triple-negative breast cancer J Xiang, MA Hurchla, F Fontana, X Su, SR Amend, AK Esser, GJ Douglas, ... Molecular cancer therapeutics 14 (11), 2473-2485, 2015 | 62 | 2015 |
Breast cancer–derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment X Su, Y Xu, GC Fox, J Xiang, KA Kwakwa, JL Davis, JI Belle, WC Lee, ... The Journal of clinical investigation 131 (20), 2021 | 60 | 2021 |
JARID2 functions as a tumor suppressor in myeloid neoplasms by repressing self-renewal in hematopoietic progenitor cells H Celik, WK Koh, AC Kramer, EL Ostrander, C Mallaney, DAC Fisher, ... Cancer cell 34 (5), 741-756. e8, 2018 | 58 | 2018 |
Noncompetitive Modulation of the Proteasome by Imidazoline Scaffolds Overcomes Bortezomib Resistance and Delays MM Tumor Growth in Vivo TA Lansdell, MA Hurchla, J Xiang, S Hovde, KN Weilbaecher, RW Henry, ... ACS chemical biology 8 (3), 578-587, 2013 | 44 | 2013 |
Nanotherapy delivery of c-myc inhibitor targets Protumor Macrophages and preserves Antitumor Macrophages in Breast Cancer AK Esser, MH Ross, F Fontana, X Su, A Gabay, GC Fox, Y Xu, J Xiang, ... Theranostics 10 (17), 7510, 2020 | 30 | 2020 |
HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice AK Esser, DA Rauch, J Xiang, JC Harding, NA Kohart, MH Ross, X Su, ... Oncotarget 8 (41), 69250, 2017 | 21 | 2017 |
Heparanase blockade as a novel dual-targeting therapy for COVID-19 J Xiang, M Lu, M Shi, X Cheng, KA Kwakwa, JL Davis, X Su, SJ Bakewell, ... Journal of virology 96 (7), e00057-22, 2022 | 19 | 2022 |
Targeted therapy to β3 integrin reduces chemoresistance in breast cancer bone metastases GC Fox, X Su, JL Davis, Y Xu, KA Kwakwa, MH Ross, F Fontana, J Xiang, ... Molecular cancer therapeutics 20 (6), 1183-1198, 2021 | 19 | 2021 |
An “off-the-shelf” CD2 universal CAR-T therapy for T-cell malignancies J Xiang, JM Devenport, AJ Carter, KW Staser, MY Kim, J O’Neal, ... Leukemia 37 (12), 2448-2456, 2023 | 16 | 2023 |
Machine learning–based scoring models to predict hematopoietic stem cell mobilization in allogeneic donors J Xiang, M Shi, MA Fiala, F Gao, MP Rettig, GL Uy, MA Schroeder, ... Blood Advances 6 (7), 1991-2000, 2022 | 15 | 2022 |
HTLV-1 viral oncogene HBZ drives bone destruction in adult T cell leukemia J Xiang, DA Rauch, DD Huey, AR Panfil, X Cheng, AK Esser, X Su, ... JCI insight 4 (19), 2019 | 15 | 2019 |
Dual-therapy with αvβ3-targeted Sn2 lipase-labile fumagillin-prodrug nanoparticles and zoledronic acid in the Vx2 rabbit tumor model AK Esser, AH Schmieder, MH Ross, J Xiang, X Su, G Cui, H Zhang, ... Nanomedicine: Nanotechnology, Biology and Medicine 12 (1), 201-211, 2016 | 15 | 2016 |
Evaluating acetate metabolism for imaging and targeting in multiple myeloma F Fontana, X Ge, X Su, D Hathi, J Xiang, S Cenci, R Civitelli, KI Shoghi, ... Clinical Cancer Research 23 (2), 416-429, 2017 | 14 | 2017 |
Mouse model recapitulates the phenotypic heterogeneity of human adult T-cell leukemia/lymphoma in bone NA Kohart, SM Elshafae, W Supsahvad, A Alasonyalilar-Demirer, ... Journal of Bone Oncology 19, 100257, 2019 | 10 | 2019 |
Parathyroid hormone-related protein promotes bone loss in T-cell leukemia as well as in solid tumors NA Kohart, SM Elshafae, AA Demirer, WP Dirksen, JT Breitbach, ST Shu, ... Leukemia & lymphoma 61 (2), 409-419, 2020 | 4 | 2020 |
Transferrin receptor in primary and metastatic breast cancer: Evaluation of expression and experimental modulation to improve molecular targeting F Fontana, AK Esser, C Egbulefu, P Karmakar, X Su, JS Allen, Y Xu, ... PloS one 18 (12), e0293700, 2023 | 3 | 2023 |
Despite Use of Upfront Plerixafor and G-CSF, Daratumumab Exposure Reduces Stem Cell Mobilization in Patients with Multiple Myeloma J Edmisson, MA Fiala, MJ Slade, A Vickroy, M Kavanaugh, C Wilson, ... Blood 140 (Supplement 1), 4295-4296, 2022 | 3 | 2022 |