Lipid nanoparticles for mRNA delivery X Hou, T Zaks, R Langer, Y Dong Nature Reviews Materials 6 (12), 1078-1094, 2021 | 1724 | 2021 |
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo H Yin, CQ Song, JR Dorkin, LJ Zhu, Y Li, Q Wu, A Park, J Yang, S Suresh, ... Nature biotechnology 34 (3), 328-333, 2016 | 948 | 2016 |
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight JE Dahlman, C Barnes, OF Khan, A Thiriot, S Jhunjunwala, TE Shaw, ... Nature nanotechnology 9 (8), 648-655, 2014 | 665 | 2014 |
Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation D Chen, KT Love, Y Chen, AA Eltoukhy, C Kastrup, G Sahay, A Jeon, ... Journal of the American Chemical Society 134 (16), 6948-6951, 2012 | 513 | 2012 |
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates Y Dong, KT Love, JR Dorkin, S Sirirungruang, Y Zhang, D Chen, ... Proceedings of the National Academy of Sciences 111 (11), 3955-3960, 2014 | 508 | 2014 |
Glucose-responsive microgels integrated with enzyme nanocapsules for closed-loop insulin delivery Z Gu, TT Dang, M Ma, BC Tang, H Cheng, S Jiang, Y Dong, Y Zhang, ... ACS nano 7 (8), 6758-6766, 2013 | 447 | 2013 |
Strategies, design, and chemistry in siRNA delivery systems Y Dong, DJ Siegwart, DG Anderson Advanced drug delivery reviews 144, 133-147, 2019 | 416 | 2019 |
A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo C Jiang, M Mei, B Li, X Zhu, W Zu, Y Tian, Q Wang, Y Guo, Y Dong, X Tan Cell research 27 (3), 440-443, 2017 | 299 | 2017 |
Lipids and lipid derivatives for RNA delivery Y Zhang, C Sun, C Wang, KE Jankovic, Y Dong Chemical Reviews 121 (20), 12181-12277, 2021 | 274 | 2021 |
Biosynthesis, total syntheses, and antitumor activity of tanshinones and their analogs as potential therapeutic agents Y Dong, SL Morris-Natschke, KH Lee Natural product reports 28 (3), 529-542, 2011 | 232 | 2011 |
An orthogonal array optimization of lipid-like nanoparticles for mRNA delivery in vivo B Li, X Luo, B Deng, J Wang, DW McComb, Y Shi, KML Gaensler, X Tan, ... Nano letters 15 (12), 8099-8107, 2015 | 222 | 2015 |
Formulation and delivery technologies for mRNA vaccines C Zeng, C Zhang, PG Walker, Y Dong mRNA Vaccines, 71-110, 2020 | 189 | 2020 |
Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis X Hou, X Zhang, W Zhao, C Zeng, B Deng, DW McComb, S Du, C Zhang, ... Nature nanotechnology 15 (1), 41-46, 2020 | 185 | 2020 |
Long-term storage of lipid-like nanoparticles for mRNA delivery P Zhao, X Hou, J Yan, S Du, Y Xue, W Li, G Xiang, Y Dong Bioactive materials 5 (2), 358-363, 2020 | 171 | 2020 |
Nanoscale platforms for messenger RNA delivery B Li, X Zhang, Y Dong Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 11 (2 …, 2019 | 157 | 2019 |
Multifunctional oncolytic nanoparticles deliver self-replicating IL-12 RNA to eliminate established tumors and prime systemic immunity Y Li, Z Su, W Zhao, X Zhang, N Momin, C Zhang, KD Wittrup, Y Dong, ... Nature Cancer 1 (9), 882-893, 2020 | 153 | 2020 |
Injectable and Glucose-Responsive Hydrogels Based on Boronic Acid–Glucose Complexation Y Dong, W Wang, O Veiseh, EA Appel, K Xue, MJ Webber, BC Tang, ... Langmuir 32 (34), 8743-8747, 2016 | 153 | 2016 |
Effects of Chemically Modified Messenger RNA on Protein Expression B Li, X Luo, Y Dong Bioconjugate chemistry 27 (3), 849-853, 2016 | 144 | 2016 |
Recent advances of antibody drug conjugates for clinical applications P Zhao, Y Zhang, W Li, C Jeanty, G Xiang, Y Dong Acta Pharmaceutica Sinica B 10 (9), 1589-1600, 2020 | 143 | 2020 |
A highly efficient and direct approach for synthesis of enantiopure β-amino alcohols by reductive cross-coupling of chiral N-tert-Butanesulfinyl imines with aldehydes YW Zhong, YZ Dong, K Fang, K Izumi, MH Xu, GQ Lin Journal of the American Chemical Society 127 (34), 11956-11957, 2005 | 137 | 2005 |