Monkeypox: disease epidemiology, host immunity and clinical interventions FM Lum, A Torres-Ruesta, MZ Tay, RTP Lin, DC Lye, L Rénia, LFP Ng Nature Reviews Immunology 22 (10), 597-613, 2022 | 263 | 2022 |
A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice TH Teo, FM Lum, C Claser, V Lulla, A Lulla, A Merits, L Rénia, LFP Ng The Journal of Immunology 190 (1), 259-269, 2013 | 249 | 2013 |
Viperin restricts chikungunya virus replication and pathology TS Teng, SS Foo, D Simamarta, FM Lum, TH Teo, A Lulla, NKW Yeo, ... The Journal of clinical investigation 122 (12), 4447-4460, 2012 | 223 | 2012 |
Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein YW Kam, FM Lum, TH Teo, WWL Lee, D Simarmata, S Harjanto, CL Chua, ... EMBO molecular medicine 4 (4), 330-343, 2012 | 218 | 2012 |
An essential role of antibodies in the control of Chikungunya virus infection FM Lum, TH Teo, WWL Lee, YW Kam, L Rénia, LFP Ng The Journal of Immunology 190 (12), 6295-6302, 2013 | 189 | 2013 |
Zika virus infects human fetal brain microglia and induces inflammation FM Lum, DKS Low, Y Fan, JJL Tan, B Lee, JKY Chan, L Rénia, F Ginhoux, ... Clinical Infectious Diseases 64 (7), 914-920, 2017 | 167 | 2017 |
Paradoxical effect of chloroquine treatment in enhancing chikungunya virus infection P Roques, SD Thiberville, L Dupuis-Maguiraga, FM Lum, K Labadie, ... Viruses 10 (5), 268, 2018 | 165 | 2018 |
Caribbean and La Reunion chikungunya virus isolates differ in their capacity to induce proinflammatory Th1 and NK cell responses and acute joint pathology TH Teo, Z Her, JJL Tan, FM Lum, WWL Lee, YH Chan, RY Ong, YW Kam, ... Journal of virology 89 (15), 7955-7969, 2015 | 131 | 2015 |
Cellular and molecular mechanisms of chikungunya pathogenesis FM Lum, LFP Ng Antiviral research 120, 165-174, 2015 | 129 | 2015 |
Reduced development of COVID-19 in children reveals molecular checkpoints gating pathogenesis illuminating potential therapeutics JB Steinman, FM Lum, PPK Ho, N Kaminski, L Steinman Proceedings of the National Academy of Sciences 117 (40), 24620-24626, 2020 | 124 | 2020 |
Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus‐specific neutralizing antibody response Z Her, TS Teng, JJL Tan, TH Teo, YW Kam, FM Lum, WWL Lee, C Gabriel, ... EMBO molecular medicine 7 (1), 24-41, 2015 | 109 | 2015 |
Specific biomarkers associated with neurological complications and congenital central nervous system abnormalities from Zika virus–infected patients in Brazil YW Kam, JA Leite, FM Lum, JJL Tan, B Lee, CC Judice, DAT Teixeira, ... The Journal of infectious diseases 216 (2), 172-181, 2017 | 101 | 2017 |
Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections YW Kam, CYP Lee, TH Teo, SW Howland, SN Amrun, FM Lum, P See, ... JCI insight 2 (8), 2017 | 89 | 2017 |
Prime-boost immunization strategies against Chikungunya virus D Hallengärd, FM Lum, BM Kümmerer, A Lulla, V Lulla, J García-Arriaza, ... Journal of virology 88 (22), 13333-13343, 2014 | 81 | 2014 |
Fingolimod treatment abrogates chikungunya virus–induced arthralgia TH Teo, YH Chan, WWL Lee, FM Lum, SN Amrun, Z Her, R Rajarethinam, ... Science Translational Medicine 9 (375), eaal1333, 2017 | 63 | 2017 |
Expanding regulatory T cells alleviates chikungunya virus-induced pathology in mice WWL Lee, TH Teo, Z Her, FM Lum, YW Kam, D Haase, L Rénia, ... Journal of virology 89 (15), 7893-7904, 2015 | 61 | 2015 |
Longitudinal study of cellular and systemic cytokine signatures to define the dynamics of a balanced immune environment during disease manifestation in Zika virus–infected patients FM Lum, DCB Lye, JJL Tan, B Lee, PY Chia, TK Chua, SN Amrun, ... The Journal of infectious diseases 218 (5), 814-824, 2018 | 52 | 2018 |
Mouse models for Chikungunya virus: deciphering immune mechanisms responsible for disease and pathology TH Teo, FM Lum, WWL Lee, LFP Ng Immunologic research 53, 136-147, 2012 | 51 | 2012 |
Antibody-mediated enhancement aggravates chikungunya virus infection and disease severity FM Lum, T Couderc, BS Chia, RY Ong, Z Her, A Chow, YS Leo, YW Kam, ... Scientific reports 8 (1), 1860, 2018 | 49 | 2018 |
Zika virus infection preferentially counterbalances human peripheral monocyte and/or NK cell activity FM Lum, D Lee, TK Chua, JJL Tan, CYP Lee, X Liu, Y Fang, B Lee, ... MSphere 3 (2), 10.1128/mspheredirect. 00120-18, 2018 | 36 | 2018 |