| Intramolecular hydrogen bonding to improve membrane permeability and absorption in beyond rule of five chemical space A Alex, DS Millan, M Perez, F Wakenhut, GA Whitlock MedChemComm 2 (7), 669-674, 2011 | 324 | 2011 |
| Rapid discovery of a novel series of Abl kinase inhibitors by application of an integrated microfluidic synthesis and screening platform B Desai, K Dixon, E Farrant, Q Feng, KR Gibson, WP van Hoorn, J Mills, ... Journal of medicinal chemistry 56 (7), 3033-3047, 2013 | 160 | 2013 |
| Catalytic asymmetric hydroboration with heterotopic PN ligands: Trends in enantioselectivity with increased steric demand JM Valk, GA Whitlock, TP Layzell, JM Brown Tetrahedron: Asymmetry 6 (10), 2593-2596, 1995 | 127 | 1995 |
| Enantioselective Synthesis of ent-Stellettamide A via a Novel Dipolar Cycloaddition Reaction of (Trimethylsilyl) diazomethane. GA Whitlock, EM Carreira The Journal of Organic Chemistry 62 (23), 7916-7917, 1997 | 79 | 1997 |
| Potent and selective nonpeptidic inhibitors of procollagen C-proteinase PV Fish, GA Allan, S Bailey, J Blagg, R Butt, MG Collis, D Greiling, ... Journal of medicinal chemistry 50 (15), 3442-3456, 2007 | 75 | 2007 |
| Novel amino-pyrazole ureas with potent in vitro and in vivo antileishmanial activity CE Mowbray, S Braillard, W Speed, PA Glossop, GA Whitlock, KR Gibson, ... Journal of medicinal chemistry 58 (24), 9615-9624, 2015 | 72 | 2015 |
| Asymmetric synthesis of cyclic ethers by rearrangement of oxonium ylides generated from chiral copper carbenoids JS Clark, M Fretwell, GA Whitlock, CJ Burns, DNA Fox Tetrahedron letters 39 (1-2), 97-100, 1998 | 70 | 1998 |
| Metalloprotease inhibitors KN Dack, MJ Fray, GA Whitlock, ML Lewis, NM Thomson US Patent 6,511,993, 2003 | 69 | 2003 |
| A concise enantioselective synthesis of the fungal metabolite (+)-decarestrictine L JS Clark, TC Fessard, GA Whitlock Tetrahedron 62 (1), 73-78, 2006 | 64 | 2006 |
| A short synthesis of (±)-decarestrictine L JS Clark, GA Whitlock Tetrahedron letters 35 (34), 6381-6382, 1994 | 62 | 1994 |
| Chloroquine–astemizole hybrids with potent in vitro and in vivo antiplasmodial activity CC Musonda, GA Whitlock, MJ Witty, R Brun, M Kaiser Bioorganic & medicinal chemistry letters 19 (2), 481-484, 2009 | 58 | 2009 |
| Quantitative chemical proteomic profiling of ubiquitin specific proteases in intact cancer cells JA Ward, L McLellan, M Stockley, KR Gibson, GA Whitlock, C Knights, ... ACS chemical biology 11 (12), 3268-3272, 2016 | 57 | 2016 |
| Design and synthesis of a pan-Janus kinase inhibitor clinical candidate (PF-06263276) suitable for inhaled and topical delivery for the treatment of inflammatory diseases of … P Jones, RI Storer, YA Sabnis, FM Wakenhut, GA Whitlock, KS England, ... Journal of Medicinal Chemistry 60 (2), 767-786, 2017 | 53 | 2017 |
| Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity CC Musonda, GA Whitlock, MJ Witty, R Brun, M Kaiser Bioorganic & medicinal chemistry letters 19 (2), 401-405, 2009 | 51 | 2009 |
| Enantioselective Synthesis of ent‐Stellettamide A: Asymmetric Dipolar Cycloadditions with Me3SiCHN2 GA Whitlock, EM Carreira Helvetica chimica acta 83 (8), 2007-2022, 2000 | 46 | 2000 |
| Pyrazolopyridines and pyrazolopyrimidines JW Coe, CM Dehnhardt, P Jones, YA Sabnis, JW Strohbach, ... US Patent 9,518,052, 2016 | 43 | 2016 |
| Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition PV Fish, C Deur, X Gan, K Greene, D Hoople, M Mackenny, KS Para, ... Bioorganic & medicinal chemistry letters 18 (8), 2562-2566, 2008 | 43 | 2008 |
| DNDI-6148: a novel benzoxaborole preclinical candidate for the treatment of visceral leishmaniasis CE Mowbray, S Braillard, PA Glossop, GA Whitlock, RT Jacobs, J Speake, ... Journal of medicinal chemistry 64 (21), 16159-16176, 2021 | 40 | 2021 |
| Understanding CYP2D6 interactions MJ de Groot, F Wakenhut, G Whitlock, R Hyland Drug discovery today 14 (19-20), 964-972, 2009 | 40 | 2009 |
| Compounds PV Fish, MJ Fray, A Stobie, F Wakenhut, GA Whitlock, MD Andrews, ... US Patent 7,378,436, 2008 | 40 | 2008 |
