| Mechanisms generating cancer genome complexity from a single cell division error NT Umbreit, CZ Zhang, LD Lynch, LJ Blaine, AM Cheng, R Tourdot, L Sun, ... Science 368 (6488), eaba0712, 2020 | 349 | 2020 |
| Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B JF Tien, NT Umbreit, DR Gestaut, AD Franck, J Cooper, L Wordeman, ... Journal of Cell Biology 189 (4), 713-723, 2010 | 250 | 2010 |
| The Ndc80 kinetochore complex directly modulates microtubule dynamics NT Umbreit, DR Gestaut, JF Tien, BS Vollmar, T Gonen, CL Asbury, ... Proceedings of the National Academy of Sciences 109 (40), 16113-16118, 2012 | 143 | 2012 |
| Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation NT Umbreit, MP Miller, JF Tien, J Cattin Ortolá, L Gui, KK Lee, S Biggins, ... Nature communications 5 (1), 4951, 2014 | 65 | 2014 |
| The Ndc80 complex bridges two Dam1 complex rings J Kim, A Zelter, NT Umbreit, A Bollozos, M Riffle, R Johnson, MJ MacCoss, ... Elife 6, e21069, 2017 | 63 | 2017 |
| The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling A Zelter, M Bonomi, JO Kim, NT Umbreit, MR Hoopmann, R Johnson, ... Nature communications 6 (1), 8673, 2015 | 60 | 2015 |
| Regulation of outer kinetochore Ndc80 complex-based microtubule attachments by the central kinetochore Mis12/MIND complex EM Kudalkar, EA Scarborough, NT Umbreit, A Zelter, DR Gestaut, M Riffle, ... Proceedings of the National Academy of Sciences 112 (41), E5583-E5589, 2015 | 56 | 2015 |
| The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling S Viswanath, M Bonomi, SJ Kim, VA Klenchin, KC Taylor, KC Yabut, ... Molecular biology of the cell 28 (23), 3298-3314, 2017 | 48 | 2017 |
| Coupling Unbiased Mutagenesis to High-throughput DNA Sequencing Uncovers Functional Domains in the Ndc80 Kinetochore Protein of Saccharomyces cerevisiae JF Tien, KK Fong, NT Umbreit, C Payen, A Zelter, CL Asbury, MJ Dunham, ... Genetics 195 (1), 159-170, 2013 | 29 | 2013 |
| Kinetochore Biorientation in Saccharomyces cerevisiae Requires a Tightly Folded Conformation of the Ndc80 Complex JF Tien, NT Umbreit, A Zelter, M Riffle, MR Hoopmann, RS Johnson, ... Genetics 198 (4), 1483-1493, 2014 | 28 | 2014 |
| Cdk1 phosphorylation of the Dam1 complex strengthens kinetochore-microtubule attachments A Gutierrez, J ook Kim, NT Umbreit, CL Asbury, TN Davis, MP Miller, ... Current Biology 30 (22), 4491-4499. e5, 2020 | 16 | 2020 |
| Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor AL Jiao, R Perales, NT Umbreit, JR Haswell, ME Piper, BD Adams, ... Rna 25 (3), 352-363, 2019 | 15 | 2019 |
| Cell biology: when your own chromosomes act like foreign DNA A Spektor, NT Umbreit, D Pellman Current Biology 27 (22), R1228-R1231, 2017 | 15 | 2017 |
| Mechanisms generating cancer genome complexity from a single cell division error. Science 368, eaba0712 NT Umbreit, CZ Zhang, LD Lynch, LJ Blaine, AM Cheng, R Tourdot, L Sun, ... | 14 | 2020 |
| Mitosis puts sisters in a strained relationship: force generation at the kinetochore NT Umbreit, TN Davis Experimental cell research 318 (12), 1361-1366, 2012 | 13 | 2012 |
| Genome jail-break triggers lockdown NT Umbreit, D Pellman Nature 550 (7676), 340-341, 2017 | 12 | 2017 |
| VTT-006, an anti-mitotic compound, binds to the Ndc80 complex and suppresses cancer cell growth in vitro LJ Laine, JHE Mäki-Jouppila, E Kutvonen, P Tiikkainen, TKM Nyholm, ... Oncoscience 8, 134, 2021 | 2 | 2021 |
| A Bayesian Integrative Structure Model of the Yeast Centrosome S Viswanath, M Bonomi, SJ Kim, VA Klenchin, K Taylor, KC Yabut, ... Biophysical Journal 114 (3), 35a, 2018 | | 2018 |
| ORC is not essential for DNA replication in human cell lines, but important for repressing Rb-E2F and Polycomb group regulated genes. A Spektor, C Zhang, N Umbreit, M Feldman, A Ahsan, Y Zhang, ... MOLECULAR BIOLOGY OF THE CELL 27, 2016 | | 2016 |
| DNA damage and chromothripsis from chromosome segregation errors. A Spektor, Z Cheng-Zhong, NT Umbreit, H Cornils, JM Francis, ... MOLECULAR BIOLOGY OF THE CELL 26, 2015 | | 2015 |
Jerry F. TienGenome Sciences Centre, BC Cancer Agency在 bcgsc.ca 的电子邮件经过验证
