c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I C Grandori, N Gomez-Roman, ZA Felton-Edkins, C Ngouenet, ... Nature cell biology 7 (3), 311-318, 2005 | 782 | 2005 |
Direct activation of RNA polymerase III transcription by c-Myc N Gomez-Roman, C Grandori, RN Eisenman, RJ White Nature 421 (6920), 290-294, 2003 | 536 | 2003 |
Direct regulation of RNA polymerase III transcription by RB, p53 and c-Myc ZA Felton-Edkins, NS Kenneth, TRP Brown, NL Daly, N Gomez-Roman, ... Cell Cycle 2 (3), 180-183, 2003 | 164 | 2003 |
A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses N Gomez-Roman, K Stevenson, L Gilmour, G Hamilton, AJ Chalmers Neuro-oncology 19 (2), 229-241, 2017 | 159 | 2017 |
Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells RD Carruthers, SU Ahmed, S Ramachandran, K Strathdee, KM Kurian, ... Cancer research 78 (17), 5060-5071, 2018 | 151 | 2018 |
Abrogation of radioresistance in glioblastoma stem-like cells by inhibition of ATM kinase R Carruthers, SU Ahmed, K Strathdee, N Gomez-Roman, ... Molecular oncology 9 (1), 192-203, 2015 | 144 | 2015 |
TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription NS Kenneth, BA Ramsbottom, N Gomez-Roman, L Marshall, PA Cole, ... Proceedings of the National Academy of Sciences 104 (38), 14917-14922, 2007 | 133 | 2007 |
Cucurbit[7]uril encapsulated cisplatin overcomes cisplatin resistance via a pharmacokinetic effect JA Plumb, B Venugopal, R Oun, N Gomez-Roman, Y Kawazoe, ... Metallomics 4 (6), 561-567, 2012 | 117 | 2012 |
Activation by c-Myc of transcription by RNA polymerases I, II and III N Gomez-Roman, ZA Felton-Edkins, NS Kenneth, SJ Goodfellow, ... Biochemical Society Symposia 73, 141-154, 2006 | 108 | 2006 |
Glioblastoma’s next top model: novel culture systems for brain cancer radiotherapy research S Caragher, AJ Chalmers, N Gomez-Roman Cancers 11 (1), 44, 2019 | 82 | 2019 |
Deregulation of RNA polymerase III transcription in cervical epithelium in response to high-risk human papillomavirus NL Daly, DA Arvanitis, JA Fairley, N Gomez-Roman, JP Morton, ... Oncogene 24 (5), 880-888, 2005 | 65 | 2005 |
Differential sensitivity of Glioma stem cells to Aurora kinase A inhibitors: implications for stem cell mitosis and centrosome dynamics M Mannino, N Gomez-Roman, H Hochegger, AJ Chalmers Stem cell research 13 (1), 135-143, 2014 | 52 | 2014 |
Dynamic telomerase gene suppression via network effects of GSK3 inhibition AE Bilsland, S Hoare, K Stevenson, J Plumb, N Gomez-Roman, ... PloS one 4 (7), e6459, 2009 | 45 | 2009 |
In vivo potentiation of glutamate-mediated neuronal damage after chronic administration of the glycolysis inhibitor iodoacetate L Massieu, N Gómez-Román, T Montiel Experimental neurology 165 (2), 257-267, 2000 | 45 | 2000 |
Hypoxia-inducible factor 1 alpha is required for the tumourigenic and aggressive phenotype associated with Rab25 expression in ovarian cancer N Gomez-Roman, NM Sahasrabudhe, F McGregor, AJ Chalmers, ... Oncotarget 7 (16), 22650, 2016 | 41 | 2016 |
Radiation responses of 2D and 3D glioblastoma cells: a novel, 3D-specific radioprotective role of VEGF/Akt signaling through functional activation of NHEJ N Gomez-Roman, MY Chong, SK Chahal, SP Caragher, MR Jackson, ... Molecular cancer therapeutics 19 (2), 575-589, 2020 | 31 | 2020 |
Cucurbit [7] uril encapsulated cisplatin overcomes resistance to cisplatin induced by Rab25 overexpression in an intraperitoneal ovarian cancer model N Gomez-Roman, F McGregor, NJ Wheate, JA Plumb Journal of Ovarian Research 8, 1-10, 2015 | 19 | 2015 |
Patient-specific 3D-printed glioblastomas N Gomez-Roman, AJ Chalmers Nature Biomedical Engineering 3 (7), 498-499, 2019 | 16 | 2019 |
Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts AL Koessinger, D Koessinger, K Stevenson, C Cloix, L Mitchell, C Nixon, ... Scientific Reports 10 (1), 15361, 2020 | 10 | 2020 |
P01. 15 Mitochondrial poisoning as a novel therapy for glioblastoma N Gomez-Roman, K Stevenson Neuro-Oncology 19 (suppl_3), iii26-iii26, 2017 | 7 | 2017 |