Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2268 | 2019 |
Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis Y Iturria-Medina, RC Sotero, PJ Toussaint, JM Mateos-Pérez, AC Evans Nature communications 7 (1), 11934, 2016 | 1011 | 2016 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 922 | 2017 |
A “mitochondrial cascade hypothesis” for sporadic Alzheimer's disease RH Swerdlow, SM Khan Medical hypotheses 63 (1), 8-20, 2004 | 854 | 2004 |
The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives RH Swerdlow, JM Burns, SM Khan Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (8 …, 2014 | 812 | 2014 |
Origin and functional consequences of the complex I defect in Parkinson's disease RH Swerdlow, JK Parks, SW Miller, RE Davis, JB Tuttle, PA Trimmer, ... Annals of Neurology: Official Journal of the American Neurological …, 1996 | 808 | 1996 |
Mitochondria and mitochondrial cascades in Alzheimer’s disease RH Swerdlow Journal of Alzheimer's Disease 62 (3), 1403-1416, 2018 | 680 | 2018 |
The Alzheimer's disease mitochondrial cascade hypothesis RH Swerdlow, JM Burns, SM Khan Journal of Alzheimer's Disease 20 (s2), S265-S279, 2010 | 605 | 2010 |
Mitochondrial abnormalities in non-alcoholic steatohepatitis SH Caldwell, RH Swerdlow, EM Khan, JC Iezzoni, EE Hespenheide, ... Journal of hepatology 31 (3), 430-434, 1999 | 602 | 1999 |
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing SC Cunnane, E Trushina, C Morland, A Prigione, G Casadesus, ... Nature reviews Drug discovery 19 (9), 609-633, 2020 | 564 | 2020 |
Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids R Rademakers, M Baker, AM Nicholson, NJ Rutherford, NC Finch, ... Nature genetics 44 (2), 200-205, 2012 | 532 | 2012 |
Right orbitofrontal tumor with pedophilia symptom and constructional apraxia sign JM Burns, RH Swerdlow Archives of neurology 60 (3), 437-440, 2003 | 529 | 2003 |
Complex I deficiency in Parkinson's disease frontal cortex WD Parker Jr, JK Parks, RH Swerdlow Brain research 1189, 215-218, 2008 | 510 | 2008 |
Plasma tau in Alzheimer disease N Mattsson, H Zetterberg, S Janelidze, PS Insel, U Andreasson, ... Neurology 87 (17), 1827-1835, 2016 | 484 | 2016 |
Cardiorespiratory fitness and brain atrophy in early Alzheimer disease JM Burns, BB Cronk, HS Anderson, JE Donnelly, GP Thomas, A Harsha, ... Neurology 71 (3), 210-216, 2008 | 471 | 2008 |
Reduced lean mass in early Alzheimer disease and its association with brain atrophy JM Burns, DK Johnson, A Watts, RH Swerdlow, WM Brooks Archives of neurology 67 (4), 428-433, 2010 | 425 | 2010 |
In vivo staging of regional amyloid deposition MJ Grothe, H Barthel, J Sepulcre, M Dyrba, O Sabri, SJ Teipel, ... Neurology 89 (20), 2031-2038, 2017 | 393 | 2017 |
Pathogenesis of Alzheimer’s disease RH Swerdlow Clinical interventions in aging 2 (3), 347-359, 2007 | 388 | 2007 |
Cybrids in Alzheimer's disease: a cellular model of the disease? RH Swerdlow, JK Parks, DS Cassarino, DJ Maguire, RS Maguire, ... Neurology 49 (4), 918-925, 1997 | 380 | 1997 |
Brain aging, Alzheimer's disease, and mitochondria RH Swerdlow Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (12 …, 2011 | 379 | 2011 |