The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes R Overbeek, T Begley, RM Butler, JV Choudhuri, HY Chuang, M Cohoon, ... Nucleic acids research 33 (17), 5691-5702, 2005 | 2299 | 2005 |
Network‐based classification of breast cancer metastasis HY Chuang, E Lee, YT Liu, D Lee, T Ideker Molecular systems biology 3 (1), 140, 2007 | 1786 | 2007 |
Inferring pathway activity toward precise disease classification E Lee, HY Chuang, JW Kim, T Ideker, D Lee PLoS computational biology 4 (11), e1000217, 2008 | 630 | 2008 |
A decade of systems biology HY Chuang, M Hofree, T Ideker Annual review of cell and developmental biology 26 (1), 721-744, 2010 | 424 | 2010 |
A reference data set of 5.4 million phased human variants validated by genetic inheritance from sequencing a three-generation 17-member pedigree MA Eberle, E Fritzilas, P Krusche, M Källberg, BL Moore, MA Bekritsky, ... Genome research 27 (1), 157-164, 2017 | 391 | 2017 |
Isaac: Ultra-fast whole genome secondary analysis on Illumina sequencing platforms C Raczy, R Petrovski, CT Saunders, I Chorny, S Kruglyak, EH Margulies, ... Bioinformatics 29 (16), 2041-2043, 2013 | 357 | 2013 |
ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth S Zhang, L Chen, B Cui, HY Chuang, J Yu, J Wang-Rodriguez, L Tang, ... PloS one 7 (3), e31127, 2012 | 292 | 2012 |
Whole genome haplotyping by dilution, amplification and sequencing F Kaper, S Swamy, B Klotzle, S Muchel, J Cottrell, M Bibikova, ... Proceedings of the National Academy of Sciences 110 (14), 5552-5557, 2013 | 106 | 2013 |
Protein networks markedly improve prediction of subcellular localization in multiple eukaryotic species KY Lee, HY Chuang, A Beyer, MK Sung, WK Huh, B Lee, T Ideker Nucleic acids research 36 (20), e136-e136, 2008 | 105 | 2008 |
Subnetwork-based analysis of chronic lymphocytic leukemia identifies pathways that associate with disease progression HY Chuang, L Rassenti, M Salcedo, K Licon, A Kohlmann, T Haferlach, ... Blood, The Journal of the American Society of Hematology 120 (13), 2639-2649, 2012 | 92 | 2012 |
B-cell activating factor and v-Myc myelocytomatosis viral oncogene homolog (c-Myc) influence progression of chronic lymphocytic leukemia W Zhang, AP Kater, GF Widhopf, HY Chuang, T Enzler, DF James, ... Proceedings of the National Academy of Sciences 107 (44), 18956-18960, 2010 | 89 | 2010 |
Pisces: an accurate and versatile variant caller for somatic and germline next-generation sequencing data T Dunn, G Berry, D Emig-Agius, Y Jiang, S Lei, A Iyer, N Udar, ... Bioinformatics 35 (9), 1579-1581, 2019 | 69 | 2019 |
Chronic lymphocytic leukemia of Eμ-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression T Enzler, AP Kater, W Zhang, GF Widhopf, HY Chuang, J Lee, E Avery, ... Blood, The Journal of the American Society of Hematology 114 (20), 4469-4476, 2009 | 69 | 2009 |
Proteome-wide discovery of mislocated proteins in cancer KY Lee, K Byun, W Hong, HY Chuang, CG Pack, E Bayarsaikhan, ... Genome research 23 (8), 1283-1294, 2013 | 62 | 2013 |
Development and validation of an ultradeep next-generation sequencing assay for testing of plasma cell-free DNA from patients with advanced cancer F Janku, S Zhang, J Waters, L Liu, HJ Huang, V Subbiah, DS Hong, ... Clinical Cancer Research 23 (18), 5648-5656, 2017 | 49 | 2017 |
Biomarkers for Diagnosis and Treatment of Chronic Lymphocytic Leukemia TJ Kipps, Z Shen, SP Briggs, T Ideker, L Rassenti, HY Chuang US Patent App. 13/058,530, 2011 | 36 | 2011 |
Identifying significant genes from microarray data HY Chuang, H Liu, S Brown, C McMunn-Coffran, CY Kao, DF Hsu Proceedings. Fourth IEEE Symposium on Bioinformatics and Bioengineering, 358-365, 2004 | 36 | 2004 |
Open-access Synthetic Spike-in mRNA-seq data for Cancer Gene Fusions WD Tembe, SJ Pond, C Legendre, HY Chuang, WS Liang, NE Kim, ... BMC Genomics 2014 (15), 824, 2014 | 27 | 2014 |
Ranking genes for discriminability on microarray data HY Chuang, HK Tsai, YF Tsai, CY Kao Journal of Information Science and Engineering 19 (6), 953-966, 2003 | 26* | 2003 |
Methods and systems for generation and error-correction of unique molecular index sets with heterogeneous molecular lengths K Wu, C Zhao, HY Chuang, A So, S Tanner, SM Gross US Patent 10,844,429, 2020 | 24 | 2020 |