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Nikki A. Thiele
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An eighteen‐membered macrocyclic ligand for actinium‐225 targeted alpha therapy
NA Thiele, V Brown, JM Kelly, A Amor‐Coarasa, U Jermilova, ...
Angewandte Chemie International Edition 56 (46), 14712-14717, 2017
2202017
Actinium-225 for targeted α therapy: coordination chemistry and current chelation approaches
NA Thiele, JJ Wilson
Cancer biotherapy & radiopharmaceuticals 33 (8), 336-348, 2018
1502018
Implementing f-block metal ions in medicine: tuning the size selectivity of expanded macrocycles
NA Thiele, JJ Woods, JJ Wilson
Inorganic Chemistry 58 (16), 10483-10500, 2019
682019
Towards the stable chelation of radium for biomedical applications with an 18-membered macrocyclic ligand
DS Abou, NA Thiele, NT Gutsche, A Villmer, H Zhang, JJ Woods, ...
Chemical science 12 (10), 3733-3742, 2021
672021
A single dose of 225Ac-RPS-074 induces a complete tumor response in an LNCaP xenograft model
JM Kelly, A Amor-Coarasa, S Ponnala, A Nikolopoulou, C Williams, ...
Journal of Nuclear Medicine 60 (5), 649-655, 2019
672019
Establishing radiolanthanum chemistry for targeted nuclear medicine applications
E Aluicio‐Sarduy, NA Thiele, KE Martin, BA Vaughn, J Devaraj, AP Olson, ...
Chemistry–A European Journal 26 (6), 1238-1242, 2020
582020
Rapid Dissolution of BaSO4 by Macropa, an 18-Membered Macrocycle with High Affinity for Ba2+
NA Thiele, SN MacMillan, JJ Wilson
Journal of the American Chemical Society 140 (49), 17071-17078, 2018
562018
Tuning the Kinetic Inertness of Bi3+ Complexes: The Impact of Donor Atoms on Diaza-18-Crown-6 Ligands as Chelators for 213Bi Targeted Alpha Therapy
DJ Fiszbein, V Brown, NA Thiele, JJ Woods, L Wharton, SN MacMillan, ...
Inorganic chemistry 60 (12), 9199-9211, 2021
312021
Secondary carbamate linker can facilitate the sustained release of dopamine from brain-targeted prodrug
NA Thiele, J Kärkkäinen, KB Sloan, J Rautio, KM Huttunen
Bioorganic & Medicinal Chemistry Letters 28 (17), 2856-2860, 2018
292018
Tuning the separation of light lanthanides using a reverse-size selective aqueous complexant
NA Thiele, DJ Fiszbein, JJ Woods, JJ Wilson
Inorganic Chemistry 59 (22), 16522-16530, 2020
282020
Elucidating the coordination chemistry of the radium ion for targeted alpha therapy
AS Ivanov, ME Simms, VS Bryantsev, PD Benny, JR Griswold, LH Delmau, ...
Chemical Communications 58 (71), 9938-9941, 2022
202022
225Ac-MACROPATATE: a novel α-particle peptide receptor radionuclide therapy for neuroendocrine tumors
AP King, NT Gutsche, N Raju, S Fayn, KE Baidoo, MM Bell, CS Olkowski, ...
Journal of Nuclear Medicine 64 (4), 549-554, 2023
192023
Understanding self-assembly and the stabilization of liquid/liquid interfaces: the importance of ligand tail branching and oil-phase solvation
UI Premadasa, YZ Ma, RL Sacci, V Bocharova, NA Thiele, B Doughty
Journal of Colloid and Interface Science 609, 807-814, 2022
192022
Synergistic direct air capture of CO2 with aqueous guanidine/amino acid solvents
D Stamberga, NA Thiele, R Custelcean
MRS Advances 7 (19), 399-403, 2022
132022
MACROPA highly stable chelator of Radium-223 and functionalization attempts for targeted treatment of cancer
D Abou, N Thiele, A Villmer, N Gustche, F Escorcia, J Wilson, D Thorek
Journal of Nuclear Medicine 61 (supplement 1), 587-587, 2020
112020
Chelating Rare-Earth Metals (Ln3+) and 225Ac3+ with the Dual-Size-Selective Macrocyclic Ligand Py2-Macrodipa
A Hu, ME Simms, V Kertesz, JJ Wilson, NA Thiele
Inorganic chemistry 61 (32), 12847-12855, 2022
92022
Tracking molecular transport across oil/aqueous interfaces: Insight into “antagonistic” binding in solvent extraction
UI Premadasa, V Bocharova, L Lin, AC Genix, WT Heller, RL Sacci, ...
The Journal of Physical Chemistry B 127 (21), 4886-4895, 2023
82023
Novel double prodrugs of the iron chelator N, N′-bis (2-hydroxybenzyl) ethylenediamine-N, N′-diacetic acid (HBED): Synthesis, characterization, and investigation of …
NA Thiele, KA Abboud, KB Sloan
European Journal of Medicinal Chemistry 118, 193-207, 2016
72016
Reining in radium for nuclear medicine: extra-large chelator development for an extra-large ion
ME Simms, MM Sibley, DM Driscoll, V Kertesz, JT Damron, AS Ivanov, ...
Inorganic Chemistry 62 (50), 20834-20843, 2023
62023
High-throughput characterization and optimization of polyamide hydrolase activity using open port sampling Interface mass spectrometry
JF Cahill, V Kertesz, P Saint-Vincent, H Valentino, E Drufva, N Thiele, ...
Journal of the American Society for Mass Spectrometry 34 (7), 1383-1391, 2023
62023
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