Discovery of new multi component reactions with combinatorial methods L Weber, K Illgen, M Almstetter Synlett 1999 (03), 366-374, 1999 | 595 | 1999 |
The application of multi-component reactions in drug discovery L Weber Current Medicinal Chemistry 9 (23), 2085-2093, 2002 | 584 | 2002 |
Multi-component reactions and evolutionary chemistry L Weber Drug discovery today 7, 143-147, 2002 | 548 | 2002 |
Synthesis of Imidazo[1, 2-a] annulated Pyridines, Pyrazines and Pyrimidines by a Novel Three Component Condensation K Groebke, L Weber, E Mehlin Synlett 661, 3635-3638, 1998 | 379 | 1998 |
The CHEMDNER corpus of chemicals and drugs and its annotation principles M Krallinger, O Rabal, F Leitner, M Vazquez, D Salgado, Z Lu, R Leaman, ... Journal of cheminformatics 7, 1-17, 2015 | 344 | 2015 |
Optimization of the Biological Activity of Combinatorial Compound Libraries by a Genetic Algorithm. L Weber, S Wallbaum, C Broger, K Gubernator ChemInform 27 (6), no-no, 1996 | 295 | 1996 |
Bleeding and thrombotic complications in the use of extracorporeal membrane oxygenation J Thomas, V Kostousov, J Teruya Seminars in thrombosis and hemostasis 44 (01), 020-029, 2018 | 257 | 2018 |
Molecular basis for the inhibition of p53 by Mdmx GM Popowicz, A Czarna, U Rothweiler, A Szwagierczak, M Krajewski, ... Cell cycle 6 (19), 2386-2392, 2007 | 178 | 2007 |
High-diversity combinatorial libraries L Weber Current Opinion in Chemical Biology 4 (3), 295-302, 2000 | 147 | 2000 |
Production of sophorose lipid by Candida (Torulopsis) apicola grown on glucose RK Hommel, L Weber, A Weiss, U Himmelreich, O Rilke, HP Kleber Journal of biotechnology 33 (2), 147-155, 1994 | 146 | 1994 |
Combinatorial docking and combinatorial chemistry: design of potent non-peptide thrombin inhibitors HJ Böhm, DW Banner, L Weber Journal of computer-aided molecular design 13, 51-56, 1999 | 136 | 1999 |
Molecular recognition at the thrombin active site: structure-based design and synthesis of potent and selective thrombin inhibitors and the X-ray crystal structures of two … U Obst, DW Banner, L Weber, F Diederich Chemistry & biology 4 (4), 287-295, 1997 | 123 | 1997 |
Photocatalytic oxygenation of hydrocarbons with (tetraarylporphyrinato) iron (III) complexes and molecular oxygen. Comparison with microsomal cytochrome P-450 mediated … L Weber, R Hommel, J Behling, G Haufe, H Hennig Journal of the American Chemical Society 116 (6), 2400-2408, 1994 | 116 | 1994 |
Synthesis of novel nonpeptidic thrombin inhibitors U Obst, P Betschmann, C Lerner, P Seiler, F Diederich, V Gramlich, ... Helvetica Chimica Acta 83 (5), 855-909, 2000 | 102 | 2000 |
Evolutionary combinatorial chemistry: application of genetic algorithms L Weber Drug Discovery Today 3 (8), 379-385, 1998 | 96 | 1998 |
Isoquinolin‐1‐one Inhibitors of the MDM2–p53 Interaction U Rothweiler, A Czarna, M Krajewski, J Ciombor, C Kalinski, V Khazak, ... ChemMedChem: Chemistry Enabling Drug Discovery 3 (7), 1118-1128, 2008 | 92 | 2008 |
Tubulysin conjugates A Dömling, L Weber US Patent 7,776,814, 2010 | 83 | 2010 |
On the industrial applications of MCRs: Molecular diversity in drug discovery and generic drug synthesis C Kalinski, M Umkehrer, L Weber, J Kolb, C Burdack, G Ross Molecular diversity 14 (3), 513-522, 2010 | 82 | 2010 |
Mdm2 and MdmX inhibitors for the treatment of cancer: a patent review (2011–present) K Zak, A Pecak, B Rys, B Wladyka, A Doemling, L Weber, TA Holak, ... Expert Opinion on Therapeutic Patents 23 (4), 425-448, 2013 | 80 | 2013 |
Design of novel, nonpeptidic thrombin inhibitors and structure of a thrombin–inhibitor complex U Obst, V Gramlich, F Diederich, L Weber, DW Banner Angewandte Chemie International Edition in English 34 (16), 1739-1742, 1995 | 75 | 1995 |