WAF1/CIP1 Is Induced in p53-mediated G1 Arrest and Apoptosis WS El-Deiry, JW Harper, PM O'Connor, VE Velculescu, CE Canman, ... Cancer research 54 (5), 1169-1174, 1994 | 2996 | 1994 |
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 CE Canman, DS Lim, KA Cimprich, Y Taya, K Tamai, K Sakaguchi, ... Science 281 (5383), 1677-1679, 1998 | 2638 | 1998 |
DNA damage induces phosphorylation of the amino terminus of p53 JD Siliciano, CE Canman, Y Taya, K Sakaguchi, E Appella, MB Kastan Genes & development 11 (24), 3471-3481, 1997 | 1065 | 1997 |
Substrate specificities and identification of putative substrates of ATM kinase family members ST Kim, DS Lim, CE Canman, MB Kastan Journal of Biological Chemistry 274 (53), 37538-37543, 1999 | 1046 | 1999 |
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation R Baskaran, LD Wood, LL Whitaker, CE Canman, SE Morgan, Y Xu, ... Nature 387 (6632), 516-519, 1997 | 690 | 1997 |
P53, cell cycle control and apoptosis: implications for cancer MB Kastan, CE Canman, CJ Leonard Cancer and Metastasis reviews 14, 3-15, 1995 | 648 | 1995 |
Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation JY Ahn, JK Schwarz, H Piwnica-Worms, CE Canman Cancer research 60 (21), 5934-5936, 2000 | 558 | 2000 |
Growth factor modulation of p53-mediated growth arrest versus apoptosis. CE Canman, TM Gilmer, SB Coutts, MB Kastan Genes & development 9 (5), 600-611, 1995 | 508 | 1995 |
Mechanism of Radiosensitization by the Chk1/2 Inhibitor AZD7762 Involves Abrogation of the G2 Checkpoint and Inhibition of Homologous Recombinational DNA … MA Morgan, LA Parsels, L Zhao, JD Parsels, MA Davis, MC Hassan, ... Cancer research 70 (12), 4972-4981, 2010 | 341 | 2010 |
The p53-dependent G1 Cell Cycle Checkpoint Pathway and Ataxia-Telangiectasia CE Canman, AC Wolff, CY Chen, AJ Fornace Jr, MB Kastan Cancer research 54 (19), 5054-5058, 1994 | 312 | 1994 |
PCAT-1, a Long Noncoding RNA, Regulates BRCA2 and Controls Homologous Recombination in Cancer JR Prensner, W Chen, MK Iyer, Q Cao, T Ma, S Han, A Sahu, R Malik, ... Cancer research 74 (6), 1651-1660, 2014 | 287 | 2014 |
The role of ATM in DNA damage responses and cancer CE Canman, DS Lim Oncogene 17 (25), 3301-3308, 1998 | 262 | 1998 |
Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain JY Ahn, X Li, HL Davis, CE Canman Journal of Biological Chemistry 277 (22), 19389-19395, 2002 | 252 | 2002 |
ATM binds to β-adaptin in cytoplasmic vesicles DS Lim, DG Kirsch, CE Canman, JH Ahn, Y Ziv, LS Newman, RB Darnell, ... Proceedings of the National Academy of Sciences 95 (17), 10146-10151, 1998 | 225 | 1998 |
Three paths to stress relief. CE Canman, MB Kastan Nature 384 (6606), 1996 | 218 | 1996 |
Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells LA Parsels, MA Morgan, DM Tanska, JD Parsels, BD Palmer, RJ Booth, ... Molecular cancer therapeutics 8 (1), 45-54, 2009 | 176 | 2009 |
REV1 and polymerase ζ facilitate homologous recombination repair S Sharma, JK Hicks, CL Chute, JR Brennan, JY Ahn, TW Glover, ... Nucleic acids research 40 (2), 682-691, 2012 | 161 | 2012 |
Reversal of apoptosis by the leukaemia-associated E2A–HLF chimaeric transcription factor T Inaba, T Inukai, T Yoshihara, H Seyschab, RA Ashmun, CE Canman, ... Nature 382 (6591), 541-544, 1996 | 157 | 1996 |
Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links JK Hicks, CL Chute, MT Paulsen, RL Ragland, NG Howlett, Q Guéranger, ... Molecular and cellular biology, 2010 | 147 | 2010 |
DNA damage responses: p53 induction, cell cycle perturbations, and apoptosis CE Canman, CY Chen, MH Lee, MB Kastan Cold Spring Harbor symposia on quantitative biology 59, 277-286, 1994 | 128 | 1994 |