Attacking pain at its source: new perspectives on opioids C Stein, M Schäfer, H Machelska Nature medicine 9 (8), 1003-1008, 2003 | 782 | 2003 |
Opioid peptide–expressing leukocytes: Identification, recruitment, and simultaneously Increasing Inhibition of inflammatory pain HL Rittner, A Brack, H Machelska, SA Mousa, M Bauer, M Schäfer, ... The Journal of the American Society of Anesthesiologists 95 (2), 500-508, 2001 | 299 | 2001 |
A nontoxic pain killer designed by modeling of pathological receptor conformations V Spahn, G Del Vecchio, D Labuz, A Rodriguez-Gaztelumendi, N Massaly, ... Science 355 (6328), 966-969, 2017 | 225 | 2017 |
Modulation of peripheral sensory neurons by the immune system: implications for pain therapy C Stein, H Machelska Pharmacological reviews 63 (4), 860-881, 2011 | 221 | 2011 |
Leukocytes in the regulation of pain and analgesia HL Rittner, H Machelska, C Stein Journal of leukocyte biology 78 (6), 1215-1222, 2005 | 219 | 2005 |
Inhibition of nitric oxide synthase attenuates the development of morphine tolerance and dependence in mice NH Majeed, B Przewłocka, H Machelska, R Przewłocki Neuropharmacology 33 (2), 189-192, 1994 | 172 | 1994 |
Different mechanisms of intrinsic pain inhibition in early and late inflammation H Machelska, JK Schopohl, SA Mousa, D Labuz, M Schäfer, C Stein Journal of neuroimmunology 141 (1-2), 30-39, 2003 | 171 | 2003 |
Inhibition of nitric oxide synthase enhances morphine antinociception in the rat spinal cord R Przewłocki, H Machelska, B Przewłocka Life sciences 53 (1), PL1-PL5, 1993 | 170 | 1993 |
Advances in achieving opioid analgesia without side effects H Machelska, MÖ Celik Frontiers in pharmacology 9, 1388, 2018 | 163 | 2018 |
Control of inflammatory pain by chemokine-mediated recruitment of opioid-containing polymorphonuclear cells A Brack, HL Rittner, H Machelska, K Leder, SA Mousa, M Schäfer, C Stein Pain 112 (3), 229-238, 2004 | 157 | 2004 |
Peripheral analgesic and antiinflammatory effects of opioids C Stein, H Machelska, M Schäfer Zeitschrift für rheumatologie 60, 416-424, 2001 | 155 | 2001 |
Relative contribution of peripheral versus central opioid receptors to antinociception D Labuz, SA Mousa, M Schäfer, C Stein, H Machelska Brain research 1160, 30-38, 2007 | 151 | 2007 |
Immunohistochemical localization of endomorphin-1 and endomorphin-2 in immune cells and spinal cord in a model of inflammatory pain SA Mousa, H Machelska, M Schäfer, C Stein Journal of neuroimmunology 126 (1-2), 5-15, 2002 | 151 | 2002 |
A pharmacological profile of the novel, peripherally‐selective k‐opioid receptor agonist, EMD 61753 A Barber, GD Bartoszyk, HM Bender, R Gottschlich, HE Greiner, J Harting, ... British journal of pharmacology 113 (4), 1317-1327, 1994 | 150 | 1994 |
Immune cell–derived opioids protect against neuropathic pain in mice D Labuz, Y Schmidt, A Schreiter, HL Rittner, SA Mousa, H Machelska The Journal of clinical investigation 119 (2), 278-286, 2009 | 145 | 2009 |
Opioid control of inflammatory pain regulated by intercellular adhesion molecule-1 H Machelska, SA Mousa, A Brack, JK Schopohl, HL Rittner, M Schäfer, ... Journal of Neuroscience 22 (13), 5588-5596, 2002 | 142 | 2002 |
Opioid receptors in immune and glial cells—implications for pain control H Machelska, MÖ Celik Frontiers in immunology 11, 300, 2020 | 134 | 2020 |
Analgesic and antiinflammatory effects of two novel κ-opioid peptides W Binder, H Machelska, S Mousa, T Schmitt, PJM Rivière, JL Junien, ... The Journal of the American Society of Anesthesiologists 94 (6), 1034-1044, 2001 | 131 | 2001 |
Peripheral opioid analgesia C Stein, H Machelska, W Binder, M Schäfer Current opinion in pharmacology 1 (1), 62-65, 2001 | 128 | 2001 |
Peripheral effects of the κ-opioid agonist EMD 61753 on pain and inflammation in rats and humans H Machelska, M Pflüger, W Weber, M Piranvisseh-Völk, JD Daubert, ... Journal of Pharmacology and Experimental Therapeutics 290 (1), 354-361, 1999 | 112 | 1999 |