| N-terminal and C-terminal modulation of Hsp90 produce dissimilar phenotypes Y Wang, SR McAlpine Chemical communications 51 (8), 1410-1413, 2015 | 77 | 2015 |
| Synthesis and antiproliferative activity of 4-substituted-piperazine-1-carbodithioate derivatives of 2, 4-diaminoquinazoline SL Cao, Y Han, CZ Yuan, Y Wang, ZK Xiahou, J Liao, RT Gao, BB Mao, ... European journal of medicinal chemistry 64, 401-409, 2013 | 64 | 2013 |
| Co-polymers of actin and tropomyosin account for a major fraction of the human actin cytoskeleton JCM Meiring, NS Bryce, Y Wang, MH Taft, DJ Manstein, SL Lau, J Stear, ... Current Biology, 2018 | 63 | 2018 |
| Chemically accessible hsp90 inhibitor that does not induce a heat shock response YC Koay, JR McConnell, Y Wang, SJ Kim, LK Buckton, F Mansour, ... ACS medicinal chemistry letters 5 (7), 771-776, 2014 | 53 | 2014 |
| Synthesis and cytotoxic activity of N-((2-methyl-4 (3H)-quinazolinon-6-yl) methyl) dithiocarbamates SL Cao, Y Wang, L Zhu, J Liao, YW Guo, LL Chen, HQ Liu, X Xu European journal of medicinal chemistry 45 (9), 3850-3857, 2010 | 44 | 2010 |
| Regulating the cytoprotective response in cancer cells using simultaneous inhibition of Hsp90 and Hsp70 Y Wang, SR McAlpine Organic & biomolecular chemistry 13 (7), 2108-2116, 2015 | 31 | 2015 |
| Heat-shock protein 90 inhibitors: will they ever succeed as chemotherapeutics? Y Wang, SR McAlpine Future medicinal chemistry 7 (2), 87-90, 2015 | 30 | 2015 |
| C-terminal heat shock protein 90 modulators produce desirable oncogenic properties Y Wang, SR McAlpine Organic & biomolecular chemistry 13 (16), 4627-4631, 2015 | 29 | 2015 |
| How selective are Hsp90 inhibitors for cancer cells over normal cells? Y Wang, YC Koay, SR McAlpine ChemMedChem, 353-357, 2017 | 23 | 2017 |
| Drug targeting the actin cytoskeleton potentiates the cytotoxicity of low dose vincristine by abrogating actin-mediated repair of spindle defects Y Wang, JH Stear, A Swain, X Xu, NS Bryce, M Carnell, IB Alieva, ... Molecular Cancer Research 18 (7), 1074-1087, 2020 | 21 | 2020 |
| Redefining the phenotype of heat shock protein 90 (Hsp90) inhibitors. Y Wang, YC Koay, SR McAlpine Chemistry-A European Journal, 2010-2013, 2017 | 19 | 2017 |
| Combining an Hsp70 inhibitor with either an N-or C-terminal Hsp90 inhibitor produces mechanistically distinct phenotypes Y Wang, SR McAlpine Organic & Biomolecular Chemistry 13 (12), 3691-3698, 2015 | 19 | 2015 |
| The N-terminal autoinhibitory module of the A1 domain in von Willebrand factor stabilizes the mechanosensor catch bond YC Zhao, H Wang, Y Wang, J Lou, LA Ju RSC Chemical Biology 3 (6), 707-720, 2022 | 15 | 2022 |
| Blocking the heat shock response and depleting HSF-1 levels through heat shock protein 90 (hsp90) inhibition: a significant advance on current hsp90 chemotherapies YC Koay, JR McConnell, Y Wang, SR McAlpine RSC advances 5 (73), 59003-59013, 2015 | 14 | 2015 |
| Recent Advances of Optical Tweezers–Based Dynamic Force Spectroscopy and Mechanical Measurement Assays for Live-Cell Mechanobiology H Wang, Y Guo, R Zou, H Hu, Y Wang, F Wang, LA Ju Frontiers in Physics 10, 771111, 2022 | 13 | 2022 |
| Fluorescence-coupled micropipette aspiration assay to examine calcium mobilization caused by red blood cell mechanosensing H Wang, P Obeidy, Z Wang, Y Zhao, Y Wang, QP Su, CD Cox, LA Ju European Biophysics Journal 51 (2), 135-146, 2022 | 13 | 2022 |
| Design, synthesis and anticancer mechanistic studies of linked azoles MA Islam, Y Zhang, Y Wang, SR McAlpine MedChemComm 6 (2), 300-305, 2015 | 12 | 2015 |
| Targeting the actin/tropomyosin cytoskeleton in epithelial ovarian cancer reveals multiple mechanisms of synergy with anti-microtubule agents X Xu, Y Wang, NS Bryce, K Tang, NS Meagher, EY Kang, LE Kelemen, ... British Journal of Cancer 125 (2), 265-276, 2021 | 11 | 2021 |
| The fungal natural product (1S, 3S)-austrocortirubin induces DNA damage in HCT116 cells via a mechanism unique from other DNA damaging agents Y Wang, MA Islam, RA Davis, SR McAlpine Bioorganic & medicinal chemistry letters 25 (2), 249-253, 2015 | 10 | 2015 |
| Novel Movable Typing for Personalized Vein‐Chips in Large Scale: Recapitulate Patient‐Specific Virchow's Triad and its Contribution to Cerebral Venous Sinus Thrombosis YC Zhao, Y Zhang, Z Wang, F Jiang, K Kyanian, SSS Aye, T Hong, ... Advanced Functional Materials 33 (23), 2214179, 2023 | 9 | 2023 |
