Exploiting tumour hypoxia in cancer treatment JM Brown, WR Wilson Nature Reviews Cancer 4 (6), 437-447, 2004 | 3196 | 2004 |
Association of reactive oxygen species levels and radioresistance in cancer stem cells M Diehn, RW Cho, NA Lobo, T Kalisky, MJ Dorie, AN Kulp, D Qian, ... nature 458 (7239), 780-783, 2009 | 2869 | 2009 |
The unique physiology of solid tumors: opportunities (and problems) for cancer therapy JM Brown, AJ Giaccia Cancer research 58 (7), 1408-1416, 1998 | 2137 | 1998 |
The role of apoptosis in cancer development and treatment response JM Brown, LD Attardi Nature reviews cancer 5 (3), 231-237, 2005 | 1260 | 2005 |
Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 NJ Kassebaum, RM Barber, ZA Bhutta, L Dandona, PW Gething, SI Hay, ... The lancet 388 (10053), 1775-1812, 2016 | 1245 | 2016 |
Impact of diabetes on long-term prognosis in patients with unstable angina and non–Q-wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for … K Malmberg, S Yusuf, HC Gerstein, J Brown, F Zhao, D Hunt, L Piegas, ... Circulation 102 (9), 1014-1019, 2000 | 1186 | 2000 |
Apoptosis, p53, and tumor cell sensitivity to anticancer agents JM Brown, BG Wouters Cancer research 59 (7), 1391-1399, 1999 | 990 | 1999 |
The hypoxic cell: a target for selective cancer therapy—eighteenth Bruce F. Cain Memorial Award lecture JM Brown Cancer research 59 (23), 5863-5870, 1999 | 929 | 1999 |
Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of … H Wang, AA Abajobir, KH Abate, C Abbafati, KM Abbas, F Abd-Allah, ... The Lancet 390 (10100), 1084-1150, 2017 | 889 | 2017 |
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice M Kioi, H Vogel, G Schultz, RM Hoffman, GR Harsh, JM Brown The Journal of clinical investigation 120 (3), 694-705, 2010 | 875 | 2010 |
Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the Global Burden of … H Wang, ZA Bhutta, MM Coates, M Coggeshall, L Dandona, K Diallo, ... The Lancet 388 (10053), 1725-1774, 2016 | 862 | 2016 |
Mepolizumab or placebo for eosinophilic granulomatosis with polyangiitis ME Wechsler, P Akuthota, D Jayne, P Khoury, A Klion, CA Langford, ... New England Journal of Medicine 376 (20), 1921-1932, 2017 | 860 | 2017 |
Impact of pressure ulcers on quality of life in older patients: a systematic review C Gorecki, JM Brown, EA Nelson, M Briggs, L Schoonhoven, C Dealey, ... Journal of the American Geriatrics Society 57 (7), 1175-1183, 2009 | 854 | 2009 |
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect CU Kirchgessner, CK Patil, JW Evans, CA Cuomo, LM Fried, T Carter, ... Science 267 (5201), 1178-1183, 1995 | 756 | 1995 |
Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy JL Tatum International journal of radiation biology 82 (10), 699-757, 2006 | 747 | 2006 |
Pancreatic tumors show high levels of hypoxia AC Koong, VK Mehta, QT Le, GA Fisher, DJ Terris, JM Brown, AJ Bastidas, ... International Journal of Radiation Oncology* Biology* Physics 48 (4), 919-922, 2000 | 704 | 2000 |
Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation JM Brown The British journal of radiology 52 (620), 650-656, 1979 | 645 | 1979 |
scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. KA Biedermann, JR Sun, AJ Giaccia, LM Tosto, JM Brown Proceedings of the National Academy of Sciences 88 (4), 1394-1397, 1991 | 629 | 1991 |
The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved? JM Brown, DJ Carlson, DJ Brenner International Journal of Radiation Oncology* Biology* Physics 88 (2), 254-262, 2014 | 624 | 2014 |
Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies JM Brown Molecular medicine today 6 (4), 157-162, 2000 | 532 | 2000 |