Protein denaturation at the air-water interface and how to prevent it E D'Imprima, D Floris, M Joppe, R Sánchez, M Grininger, W Kühlbrandt Elife 8, e42747, 2019 | 284 | 2019 |
Engineering fungal de novo fatty acid synthesis for short chain fatty acid production J Gajewski, R Pavlovic, M Fischer, E Boles, M Grininger Nature Communications 8 (1), 14650, 2017 | 154 | 2017 |
Inhibition of the fungal fatty acid synthase type I multienzyme complex P Johansson, B Wiltschi, P Kumari, B Kessler, C Vonrhein, J Vonck, ... Proceedings of the National Academy of Sciences 105 (35), 12803-12808, 2008 | 139 | 2008 |
Engineering strategies for rational polyketide synthase design M Klaus, M Grininger Natural product reports 35 (10), 1070-1081, 2018 | 130 | 2018 |
Expanding the product portfolio of fungal type I fatty acid synthases Z Zhu, YJ Zhou, A Krivoruchko, M Grininger, ZK Zhao, J Nielsen Nature chemical biology 13 (4), 360-362, 2017 | 120 | 2017 |
Fatty acid biosynthesis: chain‐length regulation and control CS Heil, SS Wehrheim, KS Paithankar, M Grininger ChemBioChem 20 (18), 2298-2321, 2019 | 100 | 2019 |
Parameters affecting the X-ray dose absorbed by macromolecular crystals JW Murray, E Rudiño-Piñera, RL Owen, M Grininger, RBG Ravelli, ... Journal of synchrotron radiation 12 (3), 268-275, 2005 | 87 | 2005 |
Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy P Gipson, DJ Mills, R Wouts, M Grininger, J Vonck, W Kühlbrandt Proceedings of the National Academy of Sciences 107 (20), 9164-9169, 2010 | 79 | 2010 |
Engineering fatty acid synthases for directed polyketide production J Gajewski, F Buelens, S Serdjukow, M Janßen, N Cortina, H Grubmüller, ... Nature Chemical Biology 13 (4), 363-365, 2017 | 69 | 2017 |
Dodecins: a family of lumichrome binding proteins M Grininger, K Zeth, D Oesterhelt Journal of molecular biology 357 (3), 842-857, 2006 | 61 | 2006 |
Perspectives on the evolution, assembly and conformational dynamics of fatty acid synthase type I (FAS I) systems M Grininger Current Opinion in Structural Biology 25, 49-56, 2014 | 57 | 2014 |
Dodecin is the key player in flavin homeostasis of archaea M Grininger, H Staudt, P Johansson, J Wachtveitl, D Oesterhelt Journal of biological chemistry 284 (19), 13068-13076, 2009 | 56 | 2009 |
Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase P Johansson, B Mulinacci, C Koestler, R Vollrath, D Oesterhelt, ... Structure 17 (8), 1063-1074, 2009 | 54 | 2009 |
Mechanism of substrate shuttling by the acyl-carrier protein within the fatty acid mega-synthase C Anselmi, M Grininger, P Gipson, JD Faraldo-Gómez Journal of the American Chemical Society 132 (35), 12357-12364, 2010 | 48 | 2010 |
Characterization of the polyspecific transferase of murine type I fatty acid synthase (FAS) and implications for polyketide synthase (PKS) engineering A Rittner, KS Paithankar, KV Huu, M Grininger ACS chemical biology 13 (3), 723-732, 2018 | 47 | 2018 |
Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex L Ciccarelli, SR Connell, M Enderle, DJ Mills, J Vonck, M Grininger Structure 21 (7), 1251-1257, 2013 | 47 | 2013 |
An engineered fatty acid synthase combined with a carboxylic acid reductase enables de novo production of 1-octanol in Saccharomyces cerevisiae S Henritzi, M Fischer, M Grininger, M Oreb, E Boles Biotechnology for biofuels 11, 1-12, 2018 | 40 | 2018 |
Engineering of chimeric polyketide synthases using SYNZIP docking domains M Klaus, AD D’Souza, A Nivina, C Khosla, M Grininger ACS chemical biology 14 (3), 426-433, 2019 | 38 | 2019 |
Structural and biochemical characterization of a halophilic archaeal alkaline phosphatase A Wende, P Johansson, R Vollrath, M Dyall-Smith, D Oesterhelt, ... Journal of Molecular Biology 400 (1), 52-62, 2010 | 38 | 2010 |
Type I fatty acid synthase trapped in the octanoyl‐bound state A Rittner, KS Paithankar, A Himmler, M Grininger Protein science 29 (2), 589-605, 2020 | 36 | 2020 |