Massively parallel techniques for cataloguing the regulome of the human brain KG Townsley, KJ Brennand, LM Huckins Nature neuroscience 23 (12), 1509-1521, 2020 | 52 | 2020 |
The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease J Bendl, ME Hauberg, K Girdhar, E Im, JM Vicari, S Rahman, ... Nature neuroscience 25 (10), 1366-1378, 2022 | 38 | 2022 |
Chronic chemogenetic stimulation of the nucleus accumbens produces lasting reductions in binge drinking and ameliorates alcohol-related morphological and transcriptional changes DY Pozhidayeva, SP Farris, CM Goeke, EJ Firsick, KG Townsley, ... Brain sciences 10 (2), 109, 2020 | 34 | 2020 |
Preclinical and clinical evidence for suppression of alcohol intake by apremilast KB Grigsby, RA Mangieri, AJ Roberts, MF Lopez, EJ Firsick, KG Townsley, ... The Journal of Clinical Investigation 133 (6), 2023 | 32 | 2023 |
Population-level variation in enhancer expression identifies disease mechanisms in the human brain P Dong, GE Hoffman, P Apontes, J Bendl, S Rahman, MB Fernando, ... Nature genetics 54 (10), 1493-1503, 2022 | 28 | 2022 |
Effects of pharmacologically targeting neuroimmune pathways on alcohol drinking in mice selectively bred to drink to intoxication AR Ozburn, P Metten, S Potretzke, KG Townsley, YA Blednov, JC Crabbe Alcoholism: Clinical and Experimental Research 44 (2), 553-566, 2020 | 24 | 2020 |
Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk SK Powell, C O’Shea, K Townsley, I Prytkova, K Dobrindt, R Elahi, ... Molecular psychiatry 28 (5), 1970-1982, 2023 | 18 | 2023 |
Ethanol-related behaviors in mouse lines selectively bred for drinking to intoxication BE Jensen, KG Townsley, KB Grigsby, P Metten, M Chand, M Uzoekwe, ... Brain sciences 11 (2), 189, 2021 | 17 | 2021 |
Effects of chemogenetic manipulation of the nucleus accumbens core in male C57BL/6J mice KG Townsley, MB Borrego, AR Ozburn Alcohol 91, 21-27, 2021 | 15 | 2021 |
Central nucleus of the amygdala projections onto the nucleus accumbens core regulate binge-like alcohol drinking in a CRF-dependent manner MB Borrego, KB Grigsby, KG Townsley, A Chan, EJ Firsick, A Tran, ... Neuropharmacology 203, 108874, 2022 | 14 | 2022 |
Convergent impact of schizophrenia risk genes KG Townsley, A Li, PJM Deans, JF Fullard, A Yu, S Cartwright, W Zhang, ... bioRxiv, 2022.03. 29.486286, 2022 | 7 | 2022 |
From STEM to STEAM: The neuroscience behind the movement towards arts integration in K-12 Curricula KG Townsley | 7 | 2017 |
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons A Li, S Cartwright, A Yu, SM Ho, N Schrode, PJM Deans, MR Matos, ... STAR protocols 2 (2), 100580, 2021 | 6 | 2021 |
The FDA-approved drug apremilast suppresses alcohol intake: clinical and pre-clinical validation KB Grigsby, RA Mangieri, AJ Roberts, MF Lopez, A Tran, EJ Firsick, ... bioRxiv, 2021.05. 13.444033, 2021 | 6 | 2021 |
Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome S Rahman, P Dong, P Apontes, MB Fernando, R Kosoy, KG Townsley, ... Nucleic acids research 51 (20), 11142-11161, 2023 | 5 | 2023 |
Non-additive effects of schizophrenia risk genes reflect convergent downstream function PJM Deans, C Seah, J Johnson, JG Gonzalez, K Townsley, E Cao, ... medRxiv, 2023 | 4 | 2023 |
Targeting the maladaptive effects of binge drinking on circadian gene expression K Grigsby, C Ledford, T Batish, S Kanadibhotla, D Smith, E Firsick, A Tran, ... International journal of molecular sciences 23 (19), 11084, 2022 | 4 | 2022 |
From compartments to gene loops: Functions of the 3D genome in the human brain S Rahman, P Dong, P Apontes, MB Fernando, KG Townsley, K Girdhar, ... BioRxiv, 2021.10. 12.464094, 2021 | 4 | 2021 |
Population-level variation of enhancer expression identifies novel disease mechanisms in the human brain P Dong, GE Hoffman, P Apontes, J Bendl, S Rahman, MB Fernando, ... | 4 | 2021 |
Reduced LYNX1 expression in transcriptome of human iPSC-derived neural progenitors modeling fragile X syndrome K Talvio, R Minkeviciene, KG Townsley, VS Achuta, LM Huckins, ... Frontiers in Cell and Developmental Biology 10, 1034679, 2022 | 3 | 2022 |