Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors G Zhang, DT Frederick, L Wu, Z Wei, C Krepler, S Srinivasan, YC Chae, ... The Journal of clinical investigation 126 (5), 1834-1856, 2016 | 264 | 2016 |
Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells MC Caino, YC Chae, V Vaira, S Ferrero, M Nosotti, NM Martin, ... The Journal of clinical investigation 123 (7), 2907-2920, 2013 | 208 | 2013 |
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion MC Caino, JC Ghosh, YC Chae, V Vaira, DB Rivadeneira, A Faversani, ... Proceedings of the National Academy of Sciences 112 (28), 8638-8643, 2015 | 206 | 2015 |
Mitochondrial Akt regulation of hypoxic tumor reprogramming YC Chae, V Vaira, MC Caino, HY Tang, JH Seo, AV Kossenkov, ... Cancer cell 30 (2), 257-272, 2016 | 200 | 2016 |
Landscape of the mitochondrial Hsp90 metabolome in tumours YC Chae, A Angelin, S Lisanti, AV Kossenkov, KD Speicher, H Wang, ... Nature communications 4 (1), 2139, 2013 | 174 | 2013 |
Cancer stem cell metabolism: target for cancer therapy YC Chae, JH Kim BMB reports 51 (7), 319, 2018 | 157 | 2018 |
The mitochondrial unfoldase-peptidase complex ClpXP controls bioenergetics stress and metastasis JH Seo, DB Rivadeneira, MC Caino, YC Chae, DW Speicher, HY Tang, ... PLoS biology 14 (7), e1002507, 2016 | 141 | 2016 |
Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s YC Chae, MC Caino, S Lisanti, JC Ghosh, T Dohi, NN Danial, ... Cancer cell 22 (3), 331-344, 2012 | 133 | 2012 |
ITGB4-mediated metabolic reprogramming of cancer-associated fibroblasts JS Sung, CW Kang, S Kang, Y Jang, YC Chae, BG Kim, NH Cho Oncogene 39 (3), 664-676, 2020 | 112 | 2020 |
Adaptive mitochondrial reprogramming and resistance to PI3K therapy JC Ghosh, MD Siegelin, V Vaira, A Faversani, M Tavecchio, YC Chae, ... Journal of the National Cancer Institute 107 (3), dju502, 2015 | 112 | 2015 |
Phospholipase D activity regulates integrin-mediated cell spreading and migration by inducing GTP-Rac translocation to the plasma membrane YC Chae, JH Kim, KL Kim, HW Kim, HY Lee, WD Heo, T Meyer, PG Suh, ... Molecular biology of the cell 19 (7), 3111-3123, 2008 | 110 | 2008 |
Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 HK Park, NG Yoon, JE Lee, S Hu, S Yoon, SY Kim, JH Hong, D Nam, ... Experimental & molecular medicine 52 (1), 79-91, 2020 | 96 | 2020 |
Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells HK Park, JH Hong, YT Oh, SS Kim, J Yin, AJ Lee, YC Chae, JH Kim, ... Cancer research 79 (7), 1369-1382, 2019 | 94 | 2019 |
Mitochondrial HSP90 accumulation promotes vascular remodeling in pulmonary arterial hypertension O Boucherat, T Peterlini, A Bourgeois, V Nadeau, S Breuils-Bonnet, ... American journal of respiratory and critical care medicine 198 (1), 90-103, 2018 | 93 | 2018 |
Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activity YC Chae, S Lee, K Heo, SH Ha, Y Jung, JH Kim, Y Ihara, PG Suh, SH Ryu Cellular signalling 21 (12), 1818-1826, 2009 | 72 | 2009 |
Deletion of the mitochondrial chaperone TRAP-1 uncovers global reprogramming of metabolic networks S Lisanti, M Tavecchio, YC Chae, Q Liu, AK Brice, ML Thakur, ... Cell Reports 8 (3), 671-677, 2014 | 68 | 2014 |
PLCγ1: potential arbitrator of cancer progression HJ Jang, PG Suh, YJ Lee, KJ Shin, L Cocco, YC Chae Advances in biological regulation 67, 179-189, 2018 | 62 | 2018 |
RGS2 promotes formation of neurites by stimulating microtubule polymerization K Heo, SH Ha, YC Chae, S Lee, YS Oh, YH Kim, SH Kim, JH Kim, ... Cellular signalling 18 (12), 2182-2192, 2006 | 58 | 2006 |
Inhibition of muscarinic receptor-linked phospholipase D activation by association with tubulin YC Chae, S Lee, HY Lee, K Heo, JH Kim, JH Kim, PG Suh, SH Ryu Journal of Biological Chemistry 280 (5), 3723-3730, 2005 | 54 | 2005 |
Epidermal growth factor increases insulin secretion and lowers blood glucose in diabetic mice HY Lee, K Yea, J Kim, BD Lee, YC Chae, HS Kim, DW Lee, SH Kim, ... Journal of cellular and molecular medicine 12 (5a), 1593-1604, 2008 | 53 | 2008 |