Hundreds of variants clustered in genomic loci and biological pathways affect human height H Lango Allen, K Estrada, G Lettre, SI Berndt, MN Weedon, F Rivadeneira, ... Nature 467 (7317), 832-838, 2010 | 2325 | 2010 |
Large-scale association analysis identifies new risk loci for coronary artery disease CARDIoGRAMplusC4D Consortium, P Deloukas, S Kanoni, C Willenborg, ... Nature genetics 45 (1), 25-33, 2013 | 1745 | 2013 |
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture K Estrada, U Styrkarsdottir, E Evangelou, YH Hsu, EL Duncan, EE Ntzani, ... Nature genetics 44 (5), 491-501, 2012 | 1299 | 2012 |
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, ... Nature genetics 50 (4), 524-537, 2018 | 1295 | 2018 |
The allelic landscape of human blood cell trait variation and links to common complex disease WJ Astle, H Elding, T Jiang, D Allen, D Ruklisa, AL Mann, D Mead, ... Cell 167 (5), 1415-1429. e19, 2016 | 1200 | 2016 |
Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study JB Richards, F Rivadeneira, M Inouye, TM Pastinen, N Soranzo, ... The Lancet 371 (9623), 1505-1512, 2008 | 804 | 2008 |
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies Nature genetics 41 (11), 1199-1206, 2009 | 789 | 2009 |
Genetic drivers of epigenetic and transcriptional variation in human immune cells L Chen, B Ge, FP Casale, L Vasquez, T Kwan, D Garrido-Martín, S Watt, ... Cell 167 (5), 1398-1414. e24, 2016 | 666 | 2016 |
Minisequencing: a specific tool for DNA analysis and diagnostics on oligonucleotide arrays T Pastinen, A Kurg, A Metspalu, L Peltonen, AC Syvänen Genome Research 7 (6), 606-614, 1997 | 596 | 1997 |
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture HF Zheng, V Forgetta, YH Hsu, K Estrada, A Rosello‐Diez, PJ Leo, ... Nature 526 (7571), 112-117, 2015 | 548 | 2015 |
A system for specific, high-throughput genotyping by allele-specific primer extension on microarrays T Pastinen, M Raitio, K Lindroos, P Tainola, L Peltonen, AC Syvänen Genome research 10 (7), 1031-1042, 2000 | 532 | 2000 |
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery HG Stunnenberg, S Abrignani, D Adams, M de Almeida, L Altucci, V Amin, ... Cell 167 (5), 1145-1149, 2016 | 522 | 2016 |
The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts JR Wagner, S Busche, B Ge, T Kwan, T Pastinen, M Blanchette Genome biology 15, 1-17, 2014 | 497 | 2014 |
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ... PLoS genetics 6 (2), e1000841, 2010 | 458 | 2010 |
Use of genome-wide association studies for drug repositioning P Sanseau, P Agarwal, MR Barnes, T Pastinen, JB Richards, LR Cardon, ... Nature biotechnology 30 (4), 317-320, 2012 | 417 | 2012 |
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia J Nordlund, CL Bäcklin, P Wahlberg, S Busche, EC Berglund, ... Genome biology 14, 1-15, 2013 | 368 | 2013 |
Genome-wide allele-specific analysis: insights into regulatory variation T Pastinen Nature Reviews Genetics 11 (8), 533-538, 2010 | 355 | 2010 |
Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease DJ Verlaan, S Berlivet, GM Hunninghake, AM Madore, M Larivière, ... The American Journal of Human Genetics 85 (3), 377-393, 2009 | 334 | 2009 |
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk FJ Couch, X Wang, L McGuffog, A Lee, C Olswold, KB Kuchenbaecker, ... PLoS genetics 9 (3), e1003212, 2013 | 331 | 2013 |
A survey of genetic and epigenetic variation affecting human gene expression T Pastinen, R Sladek, S Gurd, B Ge, P Lepage, K Lavergne, A Villeneuve, ... Physiological genomics, 2004 | 324 | 2004 |