Characterisation of the binding of [3H] methyllycaconitine: a new radioligand for labelling α7-type neuronal nicotinic acetylcholine receptors ARL Davies, DJ Hardick, IS Blagbrough, BVL Potter, AJ Wolstenholme, ... Neuropharmacology 38 (5), 679-690, 1999 | 369 | 1999 |
Rapid and sensitive ethidium bromide fluorescence quenching assay of polyamine conjugate–DNA interactions for the analysis of lipoplex formation in gene therapy AJ Geall, IS Blagbrough Journal of pharmaceutical and biomedical analysis 22 (5), 849-859, 2000 | 207 | 2000 |
Homologation of polyamines in the rapid synthesis of lipospermine conjugates and related lipoplexes AJ Geall, IS Blagbrough Tetrahedron 56 (16), 2449-2460, 2000 | 167 | 2000 |
Cassava: An appraisal of its phytochemistry and its biotechnological prospects IS Blagbrough, SAL Bayoumi, MG Rowan, JR Beeching Phytochemistry 71 (17-18), 1940-1951, 2010 | 157 | 2010 |
An autoradiographic study of the distribution of binding sites for the novel α7‐selective nicotinic radioligand [3H]‐methyllycaconitine in the mouse brain P Whiteaker, ARL Davies, MJ Marks, IS Blagbrough, BVL Potter, ... European journal of neuroscience 11 (8), 2689-2696, 1999 | 152 | 1999 |
Synthesis of Cholesteryl Polyamine Carbamates: pKa Studies and Condensation of Calf Thymus DNA AJ Geall, RJ Taylor, ME Earll, MAW Eaton, IS Blagbrough Bioconjugate Chemistry 11 (3), 314-326, 2000 | 138 | 2000 |
Nudicauline and elatine as potent norditerpenoid ligands at rat neuronal α-bungarotoxin binding sites: Importance of the 2-(methylsuccinimido) benzoyl moiety for neuronal … DJ Hardick, IS Blagbrough, G Cooper, BVL Potter, T Critchley, ... Journal of medicinal chemistry 39 (24), 4860-4866, 1996 | 127 | 1996 |
Effect of spermine conjugation on the cytotoxicity and cellular transport of acridine JG Delcros, S Tomasi, S Carrington, B Martin, J Renault, IS Blagbrough, ... Journal of medicinal chemistry 45 (23), 5098-5111, 2002 | 125 | 2002 |
Spider toxins affecting glutamate receptors: polyamines in therapeutic neurochemistry PNR Usherwood, IS Blagbrough Pharmacology & therapeutics 52 (2), 245-268, 1991 | 125 | 1991 |
Constituents and secondary metabolite natural products in fresh and deteriorated cassava roots SAL Bayoumi, MG Rowan, JR Beeching, IS Blagbrough Phytochemistry 71 (5-6), 598-604, 2010 | 114 | 2010 |
The condensation reaction between isocyanates and carboxylic acids. A practical synthesis of substituted amides and anilides. IS Blagbrough, NE Mackenzie, C Ortiz, AI Scott Tetrahedron letters 27 (11), 1251-1254, 1986 | 113 | 1986 |
Practical synthesis of unsymmetrical polyamine amides IS Blagbrough, AJ Geall Tetrahedron letters 39 (5-6), 439-442, 1998 | 96 | 1998 |
Polyamines and novel polyamine conjugates interact with DNA in ways that can be exploited in non-viral gene therapy IS Blagbrough, AJ Geall, AP Neal Biochemical Society Transactions 31 (2), 397-406, 2003 | 94 | 2003 |
The regiochemical distribution of positive charges along cholesterol polyamine carbamates plays significant roles in modulating DNA binding affinity and lipofection AJ Geall, MAW Eaton, T Baker, C Catterall, IS Blagbrough FEBS letters 459 (3), 337-342, 1999 | 87 | 1999 |
Multiple DNA binding modes of anthracene-9-carbonyl-N1-spermine A Rodger, S Taylor, G Adlam, IS Blagbrough, IS Haworth Bioorganic & Medicinal Chemistry 3 (6), 861-872, 1995 | 87 | 1995 |
High-performance liquid chromatographic determination of naproxen, ibuprofen and diclofenac in plasma and synovial fluid in man IS Blagbrough, MM Daykin, M Doherty, M Pattrick, PN Shaw Journal of Chromatography B: Biomedical Sciences and Applications 578 (2 …, 1992 | 74 | 1992 |
Quantitative HPLC analysis of mebeverine, mesalazine, sulphasalazine and dispersible aspirin stored in a Venalink monitored dosage system with co-prescribed medicines MS Elmasry, IS Blagbrough, MG Rowan, HM Saleh, AA Kheir, PJ Rogers Journal of pharmaceutical and biomedical analysis 54 (4), 646-652, 2011 | 71 | 2011 |
Design and synthesis of hybrid compounds as novel drugs and medicines AH Alkhzem, TJ Woodman, IS Blagbrough RSC advances 12 (30), 19470-19484, 2022 | 70 | 2022 |
Electrospun matrices for localised controlled drug delivery: release of tetracycline hydrochloride from layers of polycaprolactone and poly (ethylene-co-vinyl acetate) N Alhusein, IS Blagbrough, PA De Bank Drug delivery and translational research 2, 477-488, 2012 | 70 | 2012 |
Polyamines and polyamine amides as potent selective receptor probes, novel therapeutic lead compounds and synthetic vectors in gene therapy IS Blagbrough, S CARRINGTON, AJ GEALL Pharmacy and Pharmacology Communications 3 (5‐6), 223-233, 1997 | 69 | 1997 |