| Tumor spectrum analysis in p53-mutant mice T Jacks, L Remington, BO Williams, EM Schmitt, S Halachmi, RT Bronson, ... Current biology 4 (1), 1-7, 1994 | 2450 | 1994 |
| TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth K Inoki, H Ouyang, T Zhu, C Lindvall, Y Wang, X Zhang, Q Yang, ... Cell 126 (5), 955-968, 2006 | 1599 | 2006 |
| Prostaglandin E2 Promotes Colon Cancer Cell Growth Through a Gs-Axin-β-Catenin Signaling Axis MD Castellone, H Teramoto, BO Williams, KM Druey, JS Gutkind Science 310 (5753), 1504-1510, 2005 | 1121 | 2005 |
| p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens SD Morgenbesser, BO Williams, T Jacks, RA DePinho Nature 371 (6492), 72-74, 1994 | 805 | 1994 |
| A subset of p53-deficient embryos exhibit exencephaly VP Sah, LD Attardi, GJ Mulligan, BO Williams, RT Bronson, T Jacks Nature genetics 10 (2), 175-180, 1995 | 724 | 1995 |
| Targeted disruption of the three Rb-related genes leads to loss of G1 control and immortalization J Sage, GJ Mulligan, LD Attardi, A Miller, SQ Chen, B Williams, ... Genes & development 14 (23), 3037-3050, 2000 | 721 | 2000 |
| Essential role of β-catenin in postnatal bone acquisition SL Holmen, CR Zylstra, A Mukherjee, RE Sigler, MC Faugere, ... Journal of Biological Chemistry 280 (22), 21162-21168, 2005 | 713 | 2005 |
| Lrp5 functions in bone to regulate bone mass Y Cui, PJ Niziolek, BT MacDonald, CR Zylstra, N Alenina, DR Robinson, ... Nature medicine 17 (6), 684-691, 2011 | 488 | 2011 |
| p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. RJ Slebos, MH Lee, BS Plunkett, TD Kessis, BO Williams, T Jacks, ... Proceedings of the National Academy of Sciences 91 (12), 5320-5324, 1994 | 484 | 1994 |
| Cooperative tumorigenic effects of germline mutations in Rb and p53 BO Williams, L Remington, DM Albert, S Mukai, RT Bronson, T Jacks Nature genetics 7 (4), 480-484, 1994 | 476 | 1994 |
| Targeted disruption of p107: functional overlap between p107 and Rb. MH Lee, BO Williams, G Mulligan, S Mukai, RT Bronson, N Dyson, ... Genes & development 10 (13), 1621-1632, 1996 | 456 | 1996 |
| mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging RM Castilho, CH Squarize, LA Chodosh, BO Williams, JS Gutkind Cell stem cell 5 (3), 279-289, 2009 | 430 | 2009 |
| Regulation of Wnt signaling by Sox proteins: XSox17α/β and XSox3 physically interact with β-catenin AM Zorn, GD Barish, BO Williams, P Lavender, MW Klymkowsky, ... Molecular cell 4 (4), 487-498, 1999 | 415 | 1999 |
| Decreased BMD and Limb Deformities in Mice Carrying Mutations in Both Lrp5 and Lrp6 SL Holmen, TA Giambernardi, CR Zylstra, BD Buckner‐Berghuis, ... Journal of Bone and Mineral Research 19 (12), 2033-2040, 2004 | 407 | 2004 |
| Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts RE Herrera, VP Sah, BO Williams, TP Mäkelä, RA Weinberg, T Jacks Molecular and cellular biology, 1996 | 387 | 1996 |
| Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1 (+/−) mice L Yamasaki, R Bronson, BO Williams, NJ Dyson, E Harlow, T Jacks Nature genetics 18 (4), 360-364, 1998 | 379 | 1998 |
| Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/β-catenin and PI3K/Pten signaling pathways R Wu, N Hendrix-Lucas, R Kuick, Y Zhai, DR Schwartz, A Akyol, ... Cancer cell 11 (4), 321-333, 2007 | 371 | 2007 |
| Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts Z Kabiri, G Greicius, B Madan, S Biechele, Z Zhong, H Zaribafzadeh, ... Development 141 (11), 2206-2215, 2014 | 351 | 2014 |
| Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation T Hinoi, A Akyol, BK Theisen, DO Ferguson, JK Greenson, BO Williams, ... Cancer research 67 (20), 9721-9730, 2007 | 342 | 2007 |
| Extensive contribution of Rb‐deficient cells to adult chimeric mice with limited histopathological consequences. BO Williams, EM Schmitt, L Remington, RT Bronson, DM Albert, ... The EMBO journal 13 (18), 4251-4259, 1994 | 337 | 1994 |
Sheri HolmenUniversity of Utah在 hci.utah.edu 的电子邮件经过验证
