| Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis: essential role of nitric oxide signaling A Das, L Xi, RC Kukreja Journal of Biological Chemistry 280 (13), 12944-12955, 2005 | 461 | 2005 |
| Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity PW Fisher, F Salloum, A Das, H Hyder, RC Kukreja Circulation 111 (13), 1601-1610, 2005 | 430 | 2005 |
| Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction A Abbate, FN Salloum, E Vecile, A Das, NN Hoke, S Straino, ... Circulation 117 (20), 2670-2683, 2008 | 425 | 2008 |
| Pharmacological preconditioning with sildenafil: basic mechanisms and clinical implications RC Kukreja, F Salloum, A Das, R Ockaili, C Yin, YA Bremer, PW Fisher, ... Vascular pharmacology 42 (5-6), 219-232, 2005 | 261 | 2005 |
| PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer A Das, D Durrant, FN Salloum, L Xi, RC Kukreja Pharmacology & therapeutics 147, 12-21, 2015 | 239 | 2015 |
| Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3β∗ A Das, L Xi, RC Kukreja Journal of Biological Chemistry 283 (43), 29572-29585, 2008 | 235 | 2008 |
| Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice FN Salloum, A Abbate, A Das, JE Houser, CA Mudrick, IZ Qureshi, ... American Journal of Physiology-Heart and Circulatory Physiology 294 (3 …, 2008 | 235 | 2008 |
| Rapamycin confers preconditioning-like protection against ischemia–reperfusion injury in isolated mouse heart and cardiomyocytes SA Khan, F Salloum, A Das, L Xi, GW Vetrovec, RC Kukreja Journal of molecular and cellular cardiology 41 (2), 256-264, 2006 | 221 | 2006 |
| Cardioprotection with phosphodiesterase-5 inhibition—a novel preconditioning strategy RC Kukreja, R Ockaili, F Salloum, C Yin, J Hawkins, A Das, L Xi Journal of molecular and cellular cardiology 36 (2), 165-173, 2004 | 196 | 2004 |
| Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction A Das, D Durrant, C Mitchell, E Mayton, NN Hoke, FN Salloum, MA Park, ... Proceedings of the national academy of sciences 107 (42), 18202-18207, 2010 | 183 | 2010 |
| ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice A Das, FN Salloum, L Xi, YJ Rao, RC Kukreja American journal of physiology-heart and circulatory physiology 296 (5 …, 2009 | 181 | 2009 |
| Pharmacologic inhibition of the NLRP3 inflammasome preserves cardiac function after ischemic and nonischemic injury in the mouse C Marchetti, S Toldo, J Chojnacki, E Mezzaroma, K Liu, FN Salloum, ... Journal of cardiovascular pharmacology 66 (1), 1-8, 2015 | 163 | 2015 |
| Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered … A Das, D Durrant, S Koka, FN Salloum, L Xi, RC Kukreja Journal of Biological Chemistry 289 (7), 4145-4160, 2014 | 159 | 2014 |
| Rapamycin protects against myocardial ischemia–reperfusion injury through JAK2–STAT3 signaling pathway A Das, FN Salloum, D Durrant, R Ockaili, RC Kukreja Journal of molecular and cellular cardiology 53 (6), 858-869, 2012 | 150 | 2012 |
| Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes MJ Scian, KER Stagliano, D Deb, MA Ellis, EH Carchman, A Das, ... Oncogene 23 (25), 4430-4443, 2004 | 148 | 2004 |
| Cyclic GMP-dependent protein kinase Iα attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte A Das, A Smolenski, SM Lohmann, RC Kukreja Journal of biological chemistry 281 (50), 38644-38652, 2006 | 145 | 2006 |
| Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas T Motiwala, K Ghoshal, A Das, S Majumder, D Weichenhan, YZ Wu, ... Oncogene 22 (41), 6319-6331, 2003 | 144 | 2003 |
| Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect S Koka, A Das, SG Zhu, D Durrant, L Xi, RC Kukreja Journal of Pharmacology and Experimental Therapeutics 334 (3), 1023-1030, 2010 | 130 | 2010 |
| Induction of microRNA-21 with exogenous hydrogen sulfide attenuates myocardial ischemic and inflammatory injury in mice S Toldo, A Das, E Mezzaroma, VQ Chau, C Marchetti, D Durrant, ... Circulation: Cardiovascular Genetics 7 (3), 311-320, 2014 | 127 | 2014 |
| EGR-1 forms a complex with YAP-1 and upregulates Bax expression in irradiated prostate carcinoma cells M Zagurovskaya, MM Shareef, A Das, A Reeves, S Gupta, M Sudol, ... Oncogene 28 (8), 1121-1131, 2009 | 124 | 2009 |
Rakesh KukrejaVirginia Commonwealth University在 vcu.edu 的电子邮件经过验证
