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Heather M Highland
Heather M Highland
在 unc.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
12532016
Genetic analyses of diverse populations improves discovery for complex traits
GL Wojcik, M Graff, KK Nishimura, R Tao, J Haessler, CR Gignoux, ...
Nature 570 (7762), 514-518, 2019
8082019
Rare and low-frequency coding variants alter human adult height
E Marouli, M Graff, C Medina-Gomez, KS Lo, AR Wood, TR Kjaer, RS Fine, ...
Nature 542 (7640), 186-190, 2017
6602017
The power of genetic diversity in genome-wide association studies of lipids
SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ...
Nature 600 (7890), 675-679, 2021
4642021
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
A Mahajan, J Wessel, SM Willems, W Zhao, NR Robertson, AY Chu, ...
Nature genetics 50 (4), 559-571, 2018
4262018
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
V Turcot, Y Lu, HM Highland, C Schurmann, AE Justice, RS Fine, ...
Nature genetics 50 (1), 26-41, 2018
3402018
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
P Surendran, F Drenos, R Young, H Warren, JP Cook, AK Manning, ...
Nature genetics 48 (10), 1151-1161, 2016
3242016
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
AR Majithia, J Flannick, P Shahinian, M Guo, MA Bray, P Fontanillas, ...
Proceedings of the National Academy of Sciences 111 (36), 13127-13132, 2014
1782014
Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants
HS Dashti, JL Follis, CE Smith, T Tanaka, BE Cade, DJ Gottlieb, A Hruby, ...
The American journal of clinical nutrition 101 (1), 135-143, 2015
1382015
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
A Mahajan, X Sim, HJ Ng, A Manning, MA Rivas, HM Highland, AE Locke, ...
PLoS genetics 11 (1), e1004876, 2015
1162015
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
AE Justice, T Karaderi, HM Highland, KL Young, M Graff, Y Lu, V Turcot, ...
Nature genetics 51 (3), 452-469, 2019
1012019
Genetic variants associated with quantitative glucose homeostasis traits translate to type 2 diabetes in Mexican Americans: the GUARDIAN (Genetics Underlying Diabetes in …
ND Palmer, MO Goodarzi, CD Langefeld, N Wang, X Guo, KD Taylor, ...
Diabetes 64 (5), 1853-1866, 2015
992015
Platelet-related variants identified by exomechip meta-analysis in 157,293 individuals
JD Eicher, N Chami, T Kacprowski, A Nomura, MH Chen, LR Yanek, ...
The American Journal of Human Genetics 99 (1), 40-55, 2016
972016
A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity
JP Bradfield, S Vogelezang, JF Felix, A Chesi, Ø Helgeland, M Horikoshi, ...
Human molecular genetics 28 (19), 3327-3338, 2019
922019
Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence …
KT Nead, A Li, MR Wehner, B Neupane, S Gustafsson, A Butterworth, ...
Human molecular genetics 24 (12), 3582-3594, 2015
752015
Neonatal diabetes, gallbladder agenesis, duodenal atresia, and intestinal malrotation caused by a novel homozygous mutation in RFX6
JP Concepcion, CS Reh, M Daniels, X Liu, VP Paz, H Ye, HM Highland, ...
Pediatric diabetes 15 (1), 67-72, 2014
722014
Exome genotyping identifies pleiotropic variants associated with red blood cell traits
N Chami, MH Chen, AJ Slater, JD Eicher, E Evangelou, SM Tajuddin, ...
The American Journal of Human Genetics 99 (1), 8-21, 2016
712016
Large-scale exome-wide association analysis identifies loci for white blood cell traits and pleiotropy with immune-mediated diseases
SM Tajuddin, UM Schick, JD Eicher, N Chami, A Giri, JA Brody, WD Hill, ...
The American Journal of Human Genetics 99 (1), 22-39, 2016
642016
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
A Manning, HM Highland, J Gasser, X Sim, T Tukiainen, P Fontanillas, ...
Diabetes 66 (7), 2019-2032, 2017
542017
Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: the trans-omics for precision medicine program
C Sarnowski, A Leong, LM Raffield, P Wu, PS de Vries, D DiCorpo, X Guo, ...
The American Journal of Human Genetics 105 (4), 706-718, 2019
462019
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