Data-driven hypothesis weighting increases detection power in genome-scale multiple testing N Ignatiadis, B Klaus, JB Zaugg, W Huber Nature methods 13 (7), 577-580, 2016 | 583 | 2016 |
CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma EM Noll, C Eisen, A Stenzinger, E Espinet, A Muckenhuber, C Klein, ... Nature medicine 22 (3), 278-287, 2016 | 215 | 2016 |
Metabolic shifts in residual breast cancer drive tumor recurrence KM Havas, V Milchevskaya, K Radic, A Alladin, E Kafkia, M Garcia, ... The Journal of clinical investigation 127 (6), 2091-2105, 2017 | 157 | 2017 |
miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea C Martínez, BK Rodiño-Janeiro, B Lobo, ML Stanifer, B Klaus, M Granzow, ... Gut 66 (9), 1537-1538, 2017 | 130 | 2017 |
Alternative polyadenylation diversifies post‐transcriptional regulation by selective RNA–protein interactions I Gupta, S Clauder‐Münster, B Klaus, AI Järvelin, RS Aiyar, V Benes, ... Molecular systems biology 10 (2), 719, 2014 | 125 | 2014 |
Landscape of nuclear transport receptor cargo specificity MT Mackmull, B Klaus, I Heinze, M Chokkalingam, A Beyer, RB Russell, ... Molecular systems biology 13 (12), 962, 2017 | 106 | 2017 |
Functional outcomes and quality of life after radical prostatectomy only versus a combination of prostatectomy with radiation and hormonal therapy M Adam, P Tennstedt, D Lanwehr, D Tilki, T Steuber, B Beyer, I Thederan, ... European urology 71 (3), 330-336, 2017 | 96 | 2017 |
Machine learning predicts the yeast metabolome from the quantitative proteome of kinase knockouts A Zelezniak, J Vowinckel, F Capuano, CB Messner, V Demichev, ... Cell systems 7 (3), 269-283. e6, 2018 | 94 | 2018 |
A genome-wide map of mitochondrial DNA recombination in yeast ES Fritsch, CD Chabbert, B Klaus, LM Steinmetz Genetics 198 (2), 755-771, 2014 | 80 | 2014 |
Landscape and dynamics of transcription initiation in the malaria parasite Plasmodium falciparum SH Adjalley, CD Chabbert, B Klaus, V Pelechano, LM Steinmetz Cell reports 14 (10), 2463-2475, 2016 | 71 | 2016 |
Gain of CTCF-anchored chromatin loops marks the exit from naive pluripotency A Pękowska, B Klaus, W Xiang, J Severino, N Daigle, FA Klein, M Oleś, ... Cell Systems 7 (5), 482-495. e10, 2018 | 70 | 2018 |
A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain E Ercan-Herbst, J Ehrig, DC Schöndorf, A Behrendt, B Klaus, ... Acta neuropathologica communications 7, 1-19, 2019 | 64 | 2019 |
Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions IL Ibarra, NM Hollmann, B Klaus, S Augsten, B Velten, J Hennig, ... Nature communications 11 (1), 124, 2020 | 62 | 2020 |
An end to end workflow for differential gene expression using Affymetrix microarrays B Klaus, S Reisenauer F1000Research 5, 2016 | 59 | 2016 |
fdrtool: Estimation of (local) false discovery rates and higher Criticism B Klaus, K Strimmer R package version 1, 15, 2015 | 46 | 2015 |
A high‐throughput C h IP‐S eq for large‐scale chromatin studies CD Chabbert, SH Adjalley, B Klaus, ES Fritsch, I Gupta, V Pelechano, ... Molecular systems biology 11 (1), 777, 2015 | 39 | 2015 |
Signal identification for rare and weak features: higher criticism or false discovery rates? B Klaus, K Strimmer Biostatistics 14 (1), 129-143, 2013 | 34 | 2013 |
voomDDA: discovery of diagnostic biomarkers and classification of RNA-seq data G Zararsiz, D Goksuluk, B Klaus, S Korkmaz, V Eldem, E Karabulut, ... PeerJ 5, e3890, 2017 | 22 | 2017 |
Statistical relevance—relevant statistics, part I B Klaus The EMBO journal 34 (22), 2727-2730, 2015 | 16 | 2015 |
Experimentally induced hyperchloremic and DL-lactic acidosis in calves: An attempt to study the effects of oral rehydration on acid-base status L Schwedhelm, D Kirchner, B Klaus, L Bachmann Journal of dairy science 96 (4), 2464-2475, 2013 | 15 | 2013 |