GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure M Kim, MJ Platt, T Shibasaki, SE Quaggin, PH Backx, S Seino, ... Nature medicine 19 (5), 567-575, 2013 | 534 | 2013 |
MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1L613V mutation X Wu, J Simpson, JH Hong, KH Kim, NK Thavarajah, PH Backx, BG Neel, ... The Journal of clinical investigation 121 (3), 1009-1025, 2011 | 236 | 2011 |
High intensity interval and endurance training have opposing effects on markers of heart failure and cardiac remodeling in hypertensive rats TM Holloway, D Bloemberg, ML da Silva, JA Simpson, J Quadrilatero, ... PloS one 10 (3), e0121138, 2015 | 210 | 2015 |
Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFα R Aschar-Sobbi, F Izaddoustdar, AS Korogyi, Q Wang, GP Farman, ... Nature communications 6 (1), 6018, 2015 | 197 | 2015 |
Early myopathy in Duchenne muscular dystrophy is associated with elevated mitochondrial H2O2 emission during impaired oxidative phosphorylation MC Hughes, SV Ramos, PC Turnbull, IA Rebalka, A Cao, CMF Monaco, ... Journal of cachexia, sarcopenia and muscle 10 (3), 643-661, 2019 | 126 | 2019 |
The primary benefits of angiotensin-converting enzyme inhibition on cardiac remodeling occur during sleep time in murine pressure overload hypertrophy TA Martino, N Tata, JA Simpson, R Vanderlaan, F Dawood, MG Kabir, ... Journal of the American College of Cardiology 57 (20), 2020-2028, 2011 | 110 | 2011 |
Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca2+ Release and Cardiac Contractility, Independently of L-Type Ca2+ Current S Beca, PB Helli, JA Simpson, D Zhao, GP Farman, PP Jones, X Tian, ... Circulation research 109 (9), 1024-1030, 2011 | 105 | 2011 |
Iron Overload Decreases CaV1.3-Dependent L-Type Ca2+ Currents Leading to Bradycardia, Altered Electrical Conduction, and Atrial Fibrillation RA Rose, M Sellan, JA Simpson, F Izaddoustdar, C Cifelli, BK Panama, ... Circulation: Arrhythmia and Electrophysiology 4 (5), 733-742, 2011 | 94 | 2011 |
Physiological mechanisms of hyperventilation during human pregnancy D Jensen, J Duffin, YM Lam, KA Webb, JA Simpson, GAL Davies, ... Respiratory physiology & neurobiology 161 (1), 76-86, 2008 | 94 | 2008 |
Nephrin tyrosine phosphorylation is required to stabilize and restore podocyte foot process architecture LA New, CE Martin, RP Scott, MJ Platt, AK Chahi, CD Stringer, P Lu, ... Journal of the American Society of Nephrology 27 (8), 2422-2435, 2016 | 91 | 2016 |
The day/night proteome in the murine heart P Podobed, WG Pyle, S Ackloo, FJ Alibhai, EV Tsimakouridze, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2014 | 91 | 2014 |
Resveratrol supplementation improves white adipose tissue function in a depot-specific manner in Zucker diabetic fatty rats MS Beaudoin, LA Snook, AM Arkell, JA Simpson, GP Holloway, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2013 | 90 | 2013 |
Preemptive heme oxygenase-1 gene delivery reveals reduced mortality and preservation of left ventricular function 1 yr after acute myocardial infarction X Liu, JA Simpson, KR Brunt, CA Ward, SRR Hall, RT Kinobe, V Barrette, ... American Journal of Physiology-Heart and Circulatory Physiology 293 (1), H48-H59, 2007 | 90 | 2007 |
Adipose tissue insulin action and IL-6 signaling after exercise in obese mice REK Macpherson, JS Huber, S Frendo-Cumbo, JA Simpson, DC Wright Medicine & Science in Sports & Exercise 47 (10), 2034-2042, 2015 | 76 | 2015 |
Changes in serum fast and slow skeletal troponin I concentration following maximal eccentric contractions DW Chapman, JA Simpson, S Iscoe, T Robins, K Nosaka Journal of Science and Medicine in Sport 16 (1), 82-85, 2013 | 69 | 2013 |
Impairments in mitochondrial palmitoyl‐CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats MS Beaudoin, CGR Perry, AM Arkell, A Chabowski, JA Simpson, ... The Journal of physiology 592 (12), 2519-2533, 2014 | 59 | 2014 |
Strategy for analysis of cardiac troponins in biological samples with a combination of affinity chromatography and mass spectrometry R Labugger, JA Simpson, M Quick, HA Brown, CE Collier, I Neverova, ... Clinical chemistry 49 (6), 873-879, 2003 | 59 | 2003 |
Fast and slow skeletal troponin I in serum from patients with various skeletal muscle disorders: a pilot study JA Simpson, R Labugger, C Collier, RJ Brison, S Iscoe, JE Van Eyk Clinical chemistry 51 (6), 966-972, 2005 | 58 | 2005 |
Increased BRAF heterodimerization is the common pathogenic mechanism for noonan syndrome-associated RAF1 mutants X Wu, J Yin, J Simpson, KH Kim, S Gu, JH Hong, P Bayliss, PH Backx, ... Molecular and cellular biology, 2012 | 53 | 2012 |
Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain N Mistry, CD Mazer, JG Sled, AH Lazarus, LS Cahill, M Solish, YQ Zhou, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2018 | 52 | 2018 |