| Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC … WM Eldehna, MF Abo-Ashour, A Nocentini, RS El-Haggar, S Bua, ... European journal of medicinal chemistry 162, 147-160, 2019 | 90 | 2019 |
| Sulfonamide inhibitors of human carbonic anhydrases designed through a three-tails approach: improving ligand/isoform matching and selectivity of action A Bonardi, A Nocentini, S Bua, J Combs, C Lomelino, J Andring, ... Journal of medicinal chemistry 63 (13), 7422-7444, 2020 | 87 | 2020 |
| Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms A Nocentini, A Bonardi, P Gratteri, B Cerra, A Gioiello, CT Supuran Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 1453-1459, 2018 | 82 | 2018 |
| 3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico … MF Abo-Ashour, WM Eldehna, A Nocentini, A Bonardi, S Bua, HS Ibrahim, ... European Journal of Medicinal Chemistry 184, 111768, 2019 | 74 | 2019 |
| Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the … HS Ibrahim, HA Allam, WR Mahmoud, A Bonardi, A Nocentini, P Gratteri, ... European Journal of Medicinal Chemistry 152, 1-9, 2018 | 66 | 2018 |
| Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation MA Said, WM Eldehna, A Nocentini, SH Fahim, A Bonardi, AA Elgazar, ... European Journal of Medicinal Chemistry 189, 112019, 2020 | 56 | 2020 |
| 3-Methylthiazolo [3, 2-a] benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and … AAM Alkhaldi, MM Al-Sanea, A Nocentini, WM Eldehna, ZM Elsayed, ... European Journal of Medicinal Chemistry 207, 112745, 2020 | 55 | 2020 |
| Inclusion of a 5-fluorouracil moiety in nitrogenous bases derivatives as human carbonic anhydrase IX and XII inhibitors produced a targeted action against MDA-MB-231 and T47D … A Petreni, A Bonardi, C Lomelino, SM Osman, ZA ALOthman, ... European Journal of Medicinal Chemistry 190, 112112, 2020 | 53 | 2020 |
| Structural investigations on coumarins leading to chromeno [4, 3-c] pyrazol-4-ones and pyrano [4, 3-c] pyrazol-4-ones: New scaffolds for the design of the tumor-associated … A Bonardi, M Falsini, D Catarzi, F Varano, LDC Mannelli, B Tenci, ... European Journal of Medicinal Chemistry 146, 47-59, 2018 | 53 | 2018 |
| 2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies … N Chiaramonte, S Bua, M Ferraroni, A Nocentini, A Bonardi, G Bartolucci, ... European Journal of Medicinal Chemistry 151, 363-375, 2018 | 49 | 2018 |
| Novel 3-substituted coumarins as selective human carbonic anhydrase IX and XII inhibitors: Synthesis, biological and molecular dynamics analysis MA Abdelrahman, HS Ibrahim, A Nocentini, WM Eldehna, A Bonardi, ... European Journal of Medicinal Chemistry 209, 112897, 2021 | 48 | 2021 |
| Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors MA Said, WM Eldehna, A Nocentini, A Bonardi, SH Fahim, S Bua, ... European Journal of Medicinal Chemistry 185, 111843, 2020 | 46 | 2020 |
| Selective Inhibition of Helicobacter pylori Carbonic Anhydrases by Carvacrol and Thymol Could Impair Biofilm Production and the Release of Outer Membrane … R Grande, S Carradori, V Puca, I Vitale, A Angeli, A Nocentini, A Bonardi, ... International journal of molecular sciences 22 (21), 11583, 2021 | 44 | 2021 |
| The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors A Pustenko, A Nocentini, P Gratteri, A Bonardi, I Vozny, R Žalubovskis, ... Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1011-1020, 2020 | 33 | 2020 |
| Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII T Al-Warhi, MM Elbadawi, A Bonardi, A Nocentini, AA Al-Karmalawy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2635-2643, 2022 | 31 | 2022 |
| Benzoxaboroles: New Potent Inhibitors of the Carbonic Anhydrases of the Pathogenic Bacterium Vibrio cholerae A Bonardi, A Nocentini, R Cadoni, S Del Prete, P Dumy, C Capasso, ... ACS Medicinal Chemistry Letters 11 (11), 2277-2284, 2020 | 29 | 2020 |
| N-Nitrosulfonamides as Carbonic Anhydrase Inhibitors: A Promising Chemotype for Targeting Chagas Disease and Leishmaniasis A Bonardi, AB Vermelho, V da Silva Cardoso, MC de Souza Pereira, ... ACS Medicinal Chemistry Letters 10 (4), 413-418, 2018 | 29 | 2018 |
| Pharmaceutical strategies for preventing toxicity and promoting antioxidant and anti-inflammatory actions of bilirubin A Nocentini, A Bonardi, S Pratesi, P Gratteri, C Dani, CT Supuran Journal of enzyme inhibition and medicinal chemistry 37 (1), 487-501, 2022 | 28 | 2022 |
| Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5 (4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX … WM Eldehna, MA Abdelrahman, A Nocentini, S Bua, ST Al-Rashood, ... Bioorganic Chemistry 90, 103102, 2019 | 26 | 2019 |
| Novel benzenesulfonamides aryl and arylsulfone conjugates adopting tail/dual tail approaches: synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies AH Eldeeb, MF Abo-Ashour, A Angeli, A Bonardi, DS Lasheen, ... European Journal of Medicinal Chemistry 221, 113486, 2021 | 23 | 2021 |
