| p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes JLE Dean, M Brook, AR Clark, J Saklatvala Journal of Biological Chemistry 274 (1), 264-269, 1999 | 617 | 1999 |
| Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability KR Mahtani, M Brook, JLE Dean, G Sully, J Saklatvala, AR Clark Molecular and cellular biology 21 (19), 6461-6469, 2001 | 560 | 2001 |
| Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade M Lasa, KR Mahtani, A Finch, G Brewer, J Saklatvala, AR Clark Molecular and cellular biology, 2000 | 534 | 2000 |
| Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1 SM Abraham, T Lawrence, A Kleiman, P Warden, M Medghalchi, ... The Journal of experimental medicine 203 (8), 1883, 2006 | 491 | 2006 |
| Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression … E Hitti, T Iakovleva, M Brook, S Deppenmeier, AD Gruber, D Radzioch, ... Molecular and cellular biology, 2006 | 489 | 2006 |
| Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38 M Lasa, SM Abraham, C Boucheron, J Saklatvala, AR Clark Molecular and cellular biology, 2002 | 483 | 2002 |
| Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis S Alivernini, L MacDonald, A Elmesmari, S Finlay, B Tolusso, MR Gigante, ... Nature medicine 26 (8), 1295-1306, 2020 | 459 | 2020 |
| The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation JLE Dean, G Sully, AR Clark, J Saklatvala Cellular signalling 16 (10), 1113-1121, 2004 | 423 | 2004 |
| The 3′ untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR JLE Dean, R Wait, KR Mahtani, G Sully, AR Clark, J Saklatvala Molecular and cellular biology 21 (3), 721-730, 2001 | 375 | 2001 |
| Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38 M Lasa, M Brook, J Saklatvala, AR Clark Molecular and cellular biology, 2001 | 348 | 2001 |
| Anti-inflammatory functions of glucocorticoid-induced genes AR Clark Molecular and cellular endocrinology 275 (1-2), 79-97, 2007 | 329 | 2007 |
| Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase … M Brook, CR Tchen, T Santalucia, J McIlrath, JSC Arthur, J Saklatvala, ... Molecular and cellular biology, 2006 | 329 | 2006 |
| Nonclassical Ly6C− monocytes drive the development of inflammatory arthritis in mice AV Misharin, CM Cuda, R Saber, JD Turner, AK Gierut, GK Haines, ... Cell reports 9 (2), 591-604, 2014 | 317 | 2014 |
| Regulation of tumour necrosis factor α mRNA stability by the mitogen-activated protein kinase p38 signalling cascade M Brook, G Sully, AR Clark, J Saklatvala FEBS letters 483 (1), 57-61, 2000 | 304 | 2000 |
| Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38 AR Clark, JLE Dean, J Saklatvala FEBS letters 546 (1), 37-44, 2003 | 271 | 2003 |
| A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA SH Ridley, JLE Dean, SJ Sarsfield, M Brook, AR Clark, J Saklatvala FEBS letters 439 (1-2), 75-80, 1998 | 266 | 1998 |
| Synovial cell metabolism and chronic inflammation in rheumatoid arthritis J Falconer, AN Murphy, SP Young, AR Clark, S Tiziani, M Guma, ... Arthritis & Rheumatology 70 (7), 984-999, 2018 | 259 | 2018 |
| Maps and legends: the quest for dissociated ligands of the glucocorticoid receptor AR Clark, MG Belvisi Pharmacology & therapeutics 134 (1), 54-67, 2012 | 247 | 2012 |
| Mechanisms of steroid action and resistance in inflammation: MAP kinase phosphatase 1: a novel mediator of biological effects of glucocorticoids AR Clark J Endocrinol 178, 5-12, 2003 | 204 | 2003 |
| The stability of tristetraprolin mRNA is regulated by mitogen-activated protein kinase p38 and by tristetraprolin itself CR Tchen, M Brook, J Saklatvala, AR Clark Journal of Biological Chemistry 279 (31), 32393-32400, 2004 | 201 | 2004 |
