Crystal structure of the β2 adrenergic receptor–Gs protein complex SGF Rasmussen, BT DeVree, Y Zou, AC Kruse, KY Chung, TS Kobilka, ... Nature 477 (7366), 549-555, 2011 | 3440 | 2011 |
Structure of the µ-opioid receptor–Gi protein complex A Koehl, H Hu, S Maeda, Y Zhang, Q Qu, JM Paggi, NR Latorraca, ... Nature 558 (7711), 547-552, 2018 | 624 | 2018 |
GPCR-G protein-β-arrestin super-complex mediates sustained G protein signaling ARB Thomsen, B Plouffe, TJ Cahill, AK Shukla, JT Tarrasch, AM Dosey, ... Cell 166 (4), 907-919, 2016 | 543 | 2016 |
Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein Y Zhang, B Sun, D Feng, H Hu, M Chu, Q Qu, JT Tarrasch, S Li, ... Nature 546 (7657), 248-253, 2017 | 540 | 2017 |
Visualization of arrestin recruitment by a G-protein-coupled receptor AK Shukla, GH Westfield, K Xiao, RI Reis, LY Huang, P Tripathi-Shukla, ... Nature 512 (7513), 218-222, 2014 | 522 | 2014 |
Phase-plate cryo-EM structure of a class B GPCR–G-protein complex YL Liang, M Khoshouei, M Radjainia, Y Zhang, A Glukhova, J Tarrasch, ... Nature 546 (7656), 118-123, 2017 | 488 | 2017 |
Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system DL Akey, WC Brown, S Dutta, J Konwerski, J Jose, TJ Jurkiw, ... Science 343 (6173), 881-885, 2014 | 393 | 2014 |
Structure of a modular polyketide synthase S Dutta, JR Whicher, DA Hansen, WA Hale, JA Chemler, GR Congdon, ... Nature 510 (7506), 512-517, 2014 | 378 | 2014 |
Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis TJ Cahill III, ARB Thomsen, JT Tarrasch, B Plouffe, AH Nguyen, F Yang, ... Proceedings of the National Academy of Sciences 114 (10), 2562-2567, 2017 | 368 | 2017 |
Structure of a signaling cannabinoid receptor 1-G protein complex KK Kumar, M Shalev-Benami, MJ Robertson, H Hu, SD Banister, ... Cell 176 (3), 448-458. e12, 2019 | 365 | 2019 |
Structure of a hallucinogen-activated Gq-coupled 5-HT2A serotonin receptor K Kim, T Che, O Panova, JF DiBerto, J Lyu, BE Krumm, D Wacker, ... Cell 182 (6), 1574-1588. e19, 2020 | 341 | 2020 |
Structure of the neurotensin receptor 1 in complex with β-arrestin 1 W Huang, M Masureel, Q Qu, J Janetzko, A Inoue, HE Kato, MJ Robertson, ... Nature 579 (7798), 303-308, 2020 | 297 | 2020 |
Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes S Maeda, Q Qu, MJ Robertson, G Skiniotis, BK Kobilka Science 364 (6440), 552-557, 2019 | 280 | 2019 |
Structural flexibility of the Gαs α-helical domain in the β2-adrenoceptor Gs complex GH Westfield, SGF Rasmussen, M Su, S Dutta, BT DeVree, KY Chung, ... Proceedings of the National Academy of Sciences 108 (38), 16086-16091, 2011 | 279 | 2011 |
Structural insights into the activation of metabotropic glutamate receptors A Koehl, H Hu, D Feng, B Sun, Y Zhang, MJ Robertson, M Chu, ... Nature 566 (7742), 79-84, 2019 | 274 | 2019 |
Structure of the M2 muscarinic receptor–β-arrestin complex in a lipid nanodisc DP Staus, H Hu, MJ Robertson, ALW Kleinhenz, LM Wingler, WD Capel, ... Nature 579 (7798), 297-302, 2020 | 273 | 2020 |
Structures of two distinct conformations of holo-non-ribosomal peptide synthetases EJ Drake, BR Miller, C Shi, JT Tarrasch, JA Sundlov, C Leigh Allen, ... Nature 529 (7585), 235-238, 2016 | 253 | 2016 |
Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates BS Strunk, CR Loucks, M Su, H Vashisth, S Cheng, J Schilling, ... Science 333 (6048), 1449-1453, 2011 | 253 | 2011 |
Inhibition of AMPK catabolic action by GSK3 T Suzuki, D Bridges, D Nakada, G Skiniotis, SJ Morrison, JD Lin, ... Molecular cell 50 (3), 407-419, 2013 | 246 | 2013 |
Structural rearrangements of a polyketide synthase module during its catalytic cycle JR Whicher, S Dutta, DA Hansen, WA Hale, JA Chemler, AM Dosey, ... Nature 510 (7506), 560-564, 2014 | 223 | 2014 |