| Tau protein disrupts nucleocytoplasmic transport in Alzheimer’s disease B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ... Neuron 99 (5), 925-940. e7, 2018 | 394 | 2018 |
| Posttranslational modifications mediate the structural diversity of tauopathy strains T Arakhamia, CE Lee, Y Carlomagno, M Kumar, DM Duong, H Wesseling, ... Cell 180 (4), 633-644. e12, 2020 | 349 | 2020 |
| Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance C Cook, Y Carlomagno, TF Gendron, J Dunmore, K Scheffel, C Stetler, ... Human molecular genetics 23 (1), 104-116, 2014 | 306 | 2014 |
| High frequency of TARDBP gene mutations in Italian patients with amyotrophic lateral sclerosis L Corrado, A Ratti, C Gellera, E Buratti, B Castellotti, Y Carlomagno, ... Human mutation 30 (4), 688-694, 2009 | 252 | 2009 |
| Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis TF Gendron, J Chew, JN Stankowski, LR Hayes, YJ Zhang, M Prudencio, ... Science translational medicine 9 (383), eaai7866, 2017 | 235 | 2017 |
| Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity YJ Zhang, L Guo, PK Gonzales, TF Gendron, Y Wu, K Jansen-West, ... Science 363 (6428), eaav2606, 2019 | 220 | 2019 |
| Mutations of FUS gene in sporadic amyotrophic lateral sclerosis L Corrado, R Del Bo, B Castellotti, A Ratti, C Cereda, S Penco, G Sorarù, ... Journal of medical genetics 47 (3), 190-194, 2010 | 219 | 2010 |
| Loss of HDAC6, a novel CHIP substrate, alleviates abnormal tau accumulation C Cook, TF Gendron, K Scheffel, Y Carlomagno, J Dunmore, M DeTure, ... Human molecular genetics 21 (13), 2936-2945, 2012 | 149 | 2012 |
| Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia M Prudencio, J Humphrey, S Pickles, AL Brown, SE Hill, JM Kachergus, ... The Journal of clinical investigation 130 (11), 2020 | 148 | 2020 |
| Acetylation: a new key to unlock tau’s role in neurodegeneration C Cook, JN Stankowski, Y Carlomagno, C Stetler, L Petrucelli Alzheimer's research & therapy 6, 1-8, 2014 | 144 | 2014 |
| Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts NJ Kramer, Y Carlomagno, YJ Zhang, S Almeida, CN Cook, TF Gendron, ... Science 353 (6300), 708-712, 2016 | 136 | 2016 |
| An acetylation–phosphorylation switch that regulates tau aggregation propensity and function Y Carlomagno, DC Chung, M Yue, M Castanedes-Casey, BJ Madden, ... Journal of Biological Chemistry 292 (37), 15277-15286, 2017 | 121 | 2017 |
| Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration N Kouri, Y Carlomagno, M Baker, AM Liesinger, RJ Caselli, ZK Wszolek, ... Acta neuropathologica 127, 271-282, 2014 | 103 | 2014 |
| The lysosomal protein cathepsin L is a progranulin protease CW Lee, JN Stankowski, J Chew, CN Cook, YW Lam, S Almeida, ... Molecular neurodegeneration 12, 1-9, 2017 | 100 | 2017 |
| TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau PEA Ash, S Lei, J Shattuck, S Boudeau, Y Carlomagno, M Medalla, ... Proceedings of the National Academy of Sciences 118 (9), e2014188118, 2021 | 99 | 2021 |
| TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans A Vaccaro, A Tauffenberger, PEA Ash, Y Carlomagno, L Petrucelli, ... PLoS genetics 8 (7), e1002806, 2012 | 94 | 2012 |
| Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases A Chang, X Xiang, J Wang, C Lee, T Arakhamia, M Simjanoska, C Wang, ... Cell 185 (8), 1346-1355. e15, 2022 | 91 | 2022 |
| A novel peripherin gene (PRPH) mutation identified in one sporadic amyotrophic lateral sclerosis patient L Corrado, Y Carlomagno, L Falasco, S Mellone, M Godi, E Cova, ... Neurobiology of aging 32 (3), 552. e1-552. e6, 2011 | 90 | 2011 |
| Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model C Cook, SS Kang, Y Carlomagno, WL Lin, M Yue, A Kurti, M Shinohara, ... Human molecular genetics 24 (21), 6198-6212, 2015 | 72 | 2015 |
| Heavy metal neurotoxicants induce ALS-linked TDP-43 pathology PEA Ash, U Dhawan, S Boudeau, S Lei, Y Carlomagno, M Knobel, ... Toxicological Sciences 167 (1), 105-115, 2019 | 54 | 2019 |
