| Transition state analogs of 5′-methylthioadenosine nucleosidase disrupt quorum sensing JA Gutierrez, T Crowder, A Rinaldo-Matthis, MC Ho, SC Almo, ... Nature chemical biology 5 (4), 251-257, 2009 | 219 | 2009 |
| Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity MC Ho, C Wilczek, JB Bonanno, L Xing, J Seznec, T Matsui, LG Carter, ... PloS one 8 (2), e57008, 2013 | 167 | 2013 |
| Small molecule inhibitors of protein arginine methyltransferases H Hu, K Qian, MC Ho, YG Zheng Expert opinion on investigational drugs 25 (3), 335-358, 2016 | 159 | 2016 |
| The origin of the electrostatic perturbation in acetoacetate decarboxylase MC Ho, JF Ménétret, H Tsuruta, KN Allen Nature 459 (7245), 393-397, 2009 | 119 | 2009 |
| Protein arginine methyltransferases: insights into the enzyme structure and mechanism at the atomic level SK Tewary, YG Zheng, MC Ho Cellular and Molecular Life Sciences 76, 2917-2932, 2019 | 116 | 2019 |
| Four generations of transition-state analogues for human purine nucleoside phosphorylase MC Ho, W Shi, A Rinaldo-Matthis, PC Tyler, GB Evans, K Clinch, SC Almo, ... Proceedings of the National Academy of Sciences 107 (11), 4805-4812, 2010 | 95 | 2010 |
| Regulatory cascade involving transcriptional and N-end rule pathways in rice under submergence CC Lin, YT Chao, WC Chen, HY Ho, MY Chou, YR Li, YL Wu, HA Yang, ... Proceedings of the National Academy of Sciences 116 (8), 3300-3309, 2019 | 93 | 2019 |
| Diamidine compounds for selective inhibition of protein arginine methyltransferase 1 L Yan, C Yan, K Qian, H Su, SA Kofsky-Wofford, WC Lee, X Zhao, MC Ho, ... Journal of medicinal chemistry 57 (6), 2611-2622, 2014 | 93 | 2014 |
| A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT ES Burgos, MC Ho, SC Almo, VL Schramm Proceedings of the National Academy of Sciences 106 (33), 13748-13753, 2009 | 88 | 2009 |
| Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model MB Cassera, KZ Hazleton, EF Merino, N Obaldia III, MC Ho, AS Murkin, ... PLoS One 6 (11), e26916, 2011 | 83 | 2011 |
| Transition state analogues in structures of ricin and saporin ribosome-inactivating proteins MC Ho, MB Sturm, SC Almo, VL Schramm Proceedings of the National Academy of Sciences 106 (48), 20276-20281, 2009 | 83 | 2009 |
| The discovery of novel heat-stable keratinases from Meiothermus taiwanensis WR-220 and other extremophiles WL Wu, MY Chen, IF Tu, YC Lin, N EswarKumar, MY Chen, MC Ho, ... Scientific reports 7 (1), 4658, 2017 | 80 | 2017 |
| Acyclic immucillin phosphonates: second-generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase KZ Hazleton, MC Ho, MB Cassera, K Clinch, DR Crump, I Rosario, ... Chemistry & biology 19 (6), 721-730, 2012 | 80 | 2012 |
| Biochemical characterization and structural analysis of a bifunctional cellulase/xylanase from Clostridium thermocellum SF Yuan, TH Wu, HL Lee, HY Hsieh, WL Lin, B Yang, CK Chang, Q Li, ... Journal of Biological Chemistry 290 (9), 5739-5748, 2015 | 73 | 2015 |
| Constructing a yeast to express the largest cellulosome complex on the cell surface M Anandharaj, YJ Lin, RP Rani, EK Nadendla, MC Ho, CC Huang, ... Proceedings of the National Academy of Sciences 117 (5), 2385-2394, 2020 | 62 | 2020 |
| Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay I Hemeon, JA Gutierrez, MC Ho, VL Schramm Analytical chemistry 83 (12), 4996-5004, 2011 | 52 | 2011 |
| Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases MC Ho, MB Cassera, DC Madrid, LM Ting, PC Tyler, K Kim, SC Almo, ... Biochemistry 48 (40), 9618-9626, 2009 | 39 | 2009 |
| Protein arginine methyltransferase 8: tetrameric structure and protein substrate specificity WC Lee, WL Lin, T Matsui, ESW Chen, TYW Wei, WH Lin, H Hu, ... Biochemistry 54 (51), 7514-7523, 2015 | 34 | 2015 |
| Performance of the new biological small-and wide-angle X-ray scattering beamline 13A at the Taiwan Photon Source O Shih, KF Liao, YQ Yeh, CJ Su, CA Wang, JW Chang, WR Wu, CC Liang, ... Applied Crystallography 55 (2), 340-352, 2022 | 31 | 2022 |
| Intricate effects of α-amino and lysine modifications on arginine methylation of the N-terminal tail of histone H4 MD Fulton, J Zhang, M He, MC Ho, YG Zheng Biochemistry 56 (28), 3539-3548, 2017 | 29 | 2017 |
