Adipose-tissue plasticity in health and disease A Sakers, MK De Siqueira, P Seale, CJ Villanueva Cell 185 (3), 419-446, 2022 | 450 | 2022 |
T cell–mediated regulation of the microbiota protects against obesity C Petersen, R Bell, KA Klag, SH Lee, R Soto, A Ghazaryan, K Buhrke, ... Science 365 (6451), eaat9351, 2019 | 316 | 2019 |
Global analysis of plasma lipids identifies liver-derived acylcarnitines as a fuel source for brown fat thermogenesis J Simcox, G Geoghegan, JA Maschek, CL Bensard, M Pasquali, R Miao, ... Cell metabolism 26 (3), 509-522. e6, 2017 | 229 | 2017 |
Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids CJ Villanueva, M Monetti, M Shih, P Zhou, SM Watkins, S Bhanot, ... Hepatology 50 (2), 434-442, 2009 | 214 | 2009 |
Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice K Minehira, SG Young, CJ Villanueva, L Yetukuri, M Oresic, ... Journal of lipid research 49 (9), 2038-2044, 2008 | 200 | 2008 |
Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs CJ Villanueva, L Vergnes, J Wang, BG Drew, C Hong, Y Tu, Y Hu, X Peng, ... Cell metabolism 17 (3), 423-435, 2013 | 174 | 2013 |
TLE3 is a dual-function transcriptional coregulator of adipogenesis CJ Villanueva, H Waki, C Godio, R Nielsen, WL Chou, L Vargas, ... Cell metabolism 13 (4), 413-427, 2011 | 163 | 2011 |
Regulation of tumor initiation by the mitochondrial pyruvate carrier CL Bensard, DR Wisidagama, KA Olson, JA Berg, NM Krah, JC Schell, ... Cell metabolism 31 (2), 284-300. e7, 2020 | 136 | 2020 |
Inhibition of adipocyte differentiation by Nur77, Nurr1, and Nor1 LC Chao, SJ Bensinger, CJ Villanueva, K Wroblewski, P Tontonoz Molecular Endocrinology 22 (12), 2596-2608, 2008 | 114 | 2008 |
Dynamic and distinct histone modifications modulate the expression of key adipogenesis regulatory genes Q Zhang, MK Ramlee, R Brunmeir, CJ Villanueva, D Halperin, F Xu Cell cycle 11 (23), 4310-4322, 2012 | 84 | 2012 |
Estrogen receptor (ER) α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression BG Drew, H Hamidi, Z Zhou, CJ Villanueva, SA Krum, AC Calkin, ... Journal of Biological Chemistry 290 (9), 5566-5581, 2015 | 81 | 2015 |
Induction of thermogenic adipocytes: molecular targets and thermogenic small molecules NJ Song, SH Chang, DY Li, CJ Villanueva, KW Park Experimental & Molecular Medicine 49 (7), e353-e353, 2017 | 73 | 2017 |
Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-γ expression and adipocyte differentiation KW Park, H Waki, CJ Villanueva, LA Monticelli, C Hong, S Kang, ... Molecular endocrinology 22 (9), 2038-2048, 2008 | 71 | 2008 |
Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism G Geoghegan, J Simcox, MM Seldin, TJ Parnell, C Stubben, S Just, ... Molecular metabolism 24, 44-63, 2019 | 68 | 2019 |
Drosophila HNF4 directs a switch in lipid metabolism that supports the transition to adulthood G Storelli, HJ Nam, J Simcox, CJ Villanueva, CS Thummel Developmental Cell 48 (2), 200-214. e6, 2019 | 59 | 2019 |
Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease MC Runtsch, MC Nelson, SH Lee, W Voth, M Alexander, R Hu, J Wallace, ... PLoS genetics 15 (2), e1007970, 2019 | 57 | 2019 |
Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis V Panic, S Pearson, J Banks, TS Tippetts, JN Velasco-Silva, S Lee, ... Elife 9, e52558, 2020 | 56 | 2020 |
Mitochondrial cardiomyopathies feature increased uptake and diminished efflux of mitochondrial calcium S Sommakia, PR Houlihan, SS Deane, JA Simcox, NS Torres, MY Jeong, ... Journal of molecular and cellular cardiology 113, 22-32, 2017 | 53 | 2017 |
Phospholipid methylation regulates muscle metabolic rate through Ca2+ transport efficiency ARP Verkerke, PJ Ferrara, CT Lin, JM Johnson, TE Ryan, JA Maschek, ... Nature metabolism 1 (9), 876-885, 2019 | 40 | 2019 |
RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs J Wang, P Rajbhandari, A Damianov, A Han, T Sallam, H Waki, ... The Journal of clinical investigation 127 (3), 987-1004, 2017 | 37 | 2017 |