ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii TF Durand-Réville, S Guler, J Comita-Prevoir, B Chen, N Bifulco, H Huynh, ... Nature microbiology 2 (9), 1-10, 2017 | 235 | 2017 |
A new platform for ultra-high density Staphylococcus aureus transposon libraries M Santiago, LM Matano, SH Moussa, MS Gilmore, S Walker, TC Meredith BMC genomics 16, 1-18, 2015 | 103 | 2015 |
Compound-gene interaction mapping reveals distinct roles for Staphylococcus aureus teichoic acids S Santa Maria JP Jr, Sadaka A, Moussa SH, Brown S, Zhang YJ, Rubin EJ ... Proc Natl Acad Sci U S A 111 (34), 12510-5, 2014 | 102* | 2014 |
Rational design of a new antibiotic class for drug-resistant infections TF Durand-Reville, AA Miller, JP O’Donnell, X Wu, MA Sylvester, S Guler, ... Nature 597 (7878), 698-702, 2021 | 90 | 2021 |
Targeting Multidrug-Resistant Acinetobacter spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent MD Barnes, V Kumar, CR Bethel, SH Moussa, J O’donnell, JD Rutter, ... MBio 10 (2), 10.1128/mbio. 00159-19, 2019 | 86* | 2019 |
Acinetobacter baumannii OmpA Is a Selective Antibiotic Permeant Porin R Iyer, SH Moussa, TF Durand-Reville, R Tommasi, A Miller ACS infectious diseases 4 (3), 373-381, 2017 | 76 | 2017 |
A synthetic lethal approach for compound and target identification in Staphylococcus aureus L Pasquina, JP Santa Maria Jr, B McKay Wood, SH Moussa, LM Matano, ... Nature chemical biology 12 (1), 40-45, 2016 | 72 | 2016 |
In Vitro Activity of Sulbactam-Durlobactam against Acinetobacter baumannii-calcoaceticus Complex Isolates Collected Globally in 2016 and 2017 SM McLeod, SH Moussa, MA Hackel, AA Miller Antimicrobial Agents and Chemotherapy 64 (4), 10.1128/aac. 02534-19, 2020 | 57 | 2020 |
Stable micron‐scale holes are a general feature of canonical holins CG Savva, JS Dewey, SH Moussa, KH To, A Holzenburg, R Young Molecular microbiology 91 (1), 57-65, 2014 | 54 | 2014 |
Active Bax and Bak are functional holins X Pang, SH Moussa, NM Targy, JL Bose, NM George, C Gries, H Lopez, ... Genes & Development 25 (21), 2278-2290, 2011 | 53 | 2011 |
Frequency and mechanism of spontaneous resistance to sulbactam combined with the novel β-lactamase inhibitor ETX2514 in clinical isolates of Acinetobacter baumannii SM McLeod, AB Shapiro, SH Moussa, M Johnstone, RE McLaughlin, ... Antimicrobial Agents and Chemotherapy 62 (2), 10.1128/aac. 01576-17, 2018 | 52 | 2018 |
Protein determinants of phage T4 lysis inhibition SH Moussa, V Kuznetsov, TAT Tran, JC Sacchettini, R Young Protein Science 21 (4), 571-582, 2012 | 49 | 2012 |
Durlobactam, a New Diazabicyclooctane β-Lactamase Inhibitor for the Treatment of Acinetobacter Infections in Combination With Sulbactam AB Shapiro, SH Moussa, SM McLeod, T Durand-Réville, AA Miller Frontiers in Microbiology 12, 709974, 2021 | 44 | 2021 |
In vitro characterization of ETX1317, a broad-spectrum β-lactamase inhibitor that restores and enhances β-lactam activity against multi-drug-resistant enterobacteriales … AA Miller, AB Shapiro, SM McLeod, NM Carter, SH Moussa, R Tommasi, ... ACS Infectious Diseases 6 (6), 1389-1397, 2020 | 35 | 2020 |
ETX2514 is a broad-spectrum betalactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Nat Microbiol 2: 17104 TF Durand-Réville, S Guler, J Comita-Prevoir, B Chen, N Bifulco, H Huynh, ... | 30 | 2017 |
Ceftazidime–avibactam resistance mutations V240G, D179Y, and D179Y/T243M in KPC-3 β-lactamase do not alter cefpodoxime–ETX1317 susceptibility AB Shapiro, SH Moussa, NM Carter, N Gao, AA Miller ACS Infectious Diseases 7 (1), 79-87, 2020 | 19 | 2020 |
Identification of the sources of< italic> Escherichia coli</italic> in a watershed using carbon-utilization patterns and composite data sets SH Moussa, R Massengale Journal of water and health 6 (2), 197-207, 2008 | 19* | 2008 |
Genetic dissection of T4 lysis SH Moussa, JL Lawler, R Young Journal of Bacteriology 196 (12), 2201-2209, 2014 | 18 | 2014 |
The structural basis of T4 phage lysis control: DNA as the signal for lysis inhibition IV Krieger, V Kuznetsov, JY Chang, J Zhang, SH Moussa, RF Young, ... Journal of molecular biology 432 (16), 4623-4636, 2020 | 17 | 2020 |
N-Hydroxyformamide LpxC inhibitors, their in vivo efficacy in a mouse Escherichia coli infection model, and their safety in a rat hemodynamic assay T Furuya, AB Shapiro, J Comita-Prevoir, EJ Kuenstner, J Zhang, SD Ribe, ... Bioorganic & Medicinal Chemistry 28 (24), 115826, 2020 | 15 | 2020 |