| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13269* | 2021 |
| Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease PK Auluck, HYE Chan, JQ Trojanowski, VMY Lee, NM Bonini Science 295 (5556), 865-868, 2002 | 1611 | 2002 |
| Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70 JM Warrick, HY Chan, GL Gray-Board, Y Chai, HL Paulson, NM Bonini Nature genetics 23 (4), 425-428, 1999 | 1055 | 1999 |
| Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila HYE Chan, JM Warrick, GL Gray-Board, HL Paulson, NM Bonini Human molecular genetics 9 (19), 2811-2820, 2000 | 413 | 2000 |
| Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila HYE Chan, JM Warrick, I Andriola, D Merry, NM Bonini Human molecular genetics 11 (23), 2895-2904, 2002 | 200 | 2002 |
| Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy JH Lu, JQ Tan, SSK Durairajan, LF Liu, ZH Zhang, L Ma, HM Shen, ... Autophagy 8 (1), 98-108, 2012 | 196 | 2012 |
| The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells PTW Law, CH Wong, TCC Au, CP Chuck, SK Kong, PKS Chan, KF To, ... Journal of general virology 86 (7), 1921-1930, 2005 | 189 | 2005 |
| Blueberry extract prolongs lifespan of Drosophila melanogaster C Peng, Y Zuo, KM Kwan, Y Liang, KY Ma, HYE Chan, Y Huang, H Yu, ... Experimental gerontology 47 (2), 170-178, 2012 | 175 | 2012 |
| CAG expansion induces nucleolar stress in polyglutamine diseases H Tsoi, TCK Lau, SY Tsang, KF Lau, HYE Chan Proceedings of the National Academy of Sciences 109 (33), 13428-13433, 2012 | 153 | 2012 |
| Green tea catechins upregulate superoxide dismutase and catalase in fruit flies YM Li, HYE Chan, Y Huang, ZY Chen Molecular nutrition & food research 51 (5), 546-554, 2007 | 150 | 2007 |
| Apple polyphenols extend the mean lifespan of Drosophila melanogaster C Peng, HYE Chan, Y Huang, H Yu, ZY Chen Journal of agricultural and food chemistry 59 (5), 2097-2106, 2011 | 135 | 2011 |
| BFA‐induced compartments from the Golgi apparatus and trans‐Golgi network/early endosome are distinct in plant cells SK Lam, Y Cai, YC Tse, J Wang, AHY Law, P Pimpl, HYE Chan, J Xia, ... The Plant Journal 60 (5), 865-881, 2009 | 124 | 2009 |
| Rationally designed small molecules that target both the DNA and RNA causing myotonic dystrophy type 1 L Nguyen, LM Luu, S Peng, JF Serrano, HYE Chan, SC Zimmerman Journal of the American Chemical Society 137 (44), 14180-14189, 2015 | 120 | 2015 |
| Drosophila models of human neurodegenerative disease HYE Chan, NM Bonini Cell Death & Differentiation 7 (11), 1075-1080, 2000 | 119 | 2000 |
| Targeting toxic RNAs that cause myotonic dystrophy type 1 (DM1) with a bisamidinium inhibitor CH Wong, L Nguyen, J Peh, LM Luu, JS Sanchez, SL Richardson, ... Journal of the American Chemical Society 136 (17), 6355-6361, 2014 | 112 | 2014 |
| The ion channel activity of the SARS-coronavirus 3a protein is linked to its pro-apoptotic function CM Chan, H Tsoi, WM Chan, S Zhai, CO Wong, X Yao, WY Chan, ... The international journal of biochemistry & cell biology 41 (11), 2232-2239, 2009 | 109 | 2009 |
| Black tea theaflavins extend the lifespan of fruit flies C Peng, HYE Chan, YM Li, Y Huang, ZY Chen Experimental gerontology 44 (12), 773-783, 2009 | 103 | 2009 |
| Mechanism for the cellular uptake of targeted gold nanorods of defined aspect ratios H Yang, Z Chen, L Zhang, WY Yung, KCF Leung, HYE Chan, CHJ Choi Small 12 (37), 5178-5189, 2016 | 92 | 2016 |
| The SARS-coronavirus membrane protein induces apoptosis through modulating the Akt survival pathway CM Chan, CW Ma, WY Chan, HYE Chan Archives of biochemistry and biophysics 459 (2), 197-207, 2007 | 92 | 2007 |
| A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia H Tsoi, CS Allen, ZS Chen, NKN Ng, AYY Chan, LYP Yuen, JM Abrigo, ... Journal of Medical Genetics 51 (9), 590-595, 2014 | 87 | 2014 |
