| p53 activation by knockdown technologies ME Robu, JD Larson, A Nasevicius, S Beiraghi, C Brenner, SA Farber, ... PLoS genetics 3 (5), e78, 2007 | 1188 | 2007 |
| NAD+ metabolism in health and disease P Belenky, KL Bogan, C Brenner Trends in biochemical sciences 32 (1), 12-19, 2007 | 1152 | 2007 |
| Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans P Bieganowski, C Brenner Cell 117 (4), 495-502, 2004 | 824 | 2004 |
| Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition KL Bogan, C Brenner Annu. Rev. Nutr. 28 (1), 115-130, 2008 | 763 | 2008 |
| Nicotinamide riboside is uniquely and orally bioavailable in mice and humans SAJ Trammell, MS Schmidt, BJ Weidemann, P Redpath, F Jaksch, ... Nature communications 7 (1), 12948, 2016 | 645 | 2016 |
| Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast AB Parsons, A Lopez, IE Givoni, DE Williams, CA Gray, J Porter, G Chua, ... Cell 126 (3), 611-625, 2006 | 562 | 2006 |
| The nitrilase superfamily: classification, structure and function HC Pace, C Brenner Genome biology 2, 1-9, 2001 | 470 | 2001 |
| Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+ P Belenky, FG Racette, KL Bogan, JM McClure, JS Smith, C Brenner Cell 129 (3), 473-484, 2007 | 460 | 2007 |
| GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction I Miyajima, M Nakafuku, N Nakayama, C Brenner, A Miyajima, K Kaibuchi, ... Cell 50 (7), 1011-1019, 1987 | 416 | 1987 |
| Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases C Brenner Biochemistry 41 (29), 9003-9014, 2002 | 344 | 2002 |
| Nicotinamide riboside opposes type 2 diabetes and neuropathy in mice SAJ Trammell, BJ Weidemann, A Chadda, MS Yorek, A Holmes, ... Scientific reports 6 (1), 26933, 2016 | 332 | 2016 |
| Circadian reprogramming in the liver identifies metabolic pathways of aging S Sato, G Solanas, FO Peixoto, L Bee, A Symeonidi, MS Schmidt, ... Cell 170 (4), 664-677. e11, 2017 | 326 | 2017 |
| Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ... Cell reports 28 (7), 1717-1728. e6, 2019 | 323 | 2019 |
| NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells J Ratajczak, M Joffraud, SAJ Trammell, R Ras, N Canela, M Boutant, ... Nature communications 7 (1), 13103, 2016 | 317 | 2016 |
| Nicotinamide improves aspects of healthspan, but not lifespan, in mice SJ Mitchell, M Bernier, MA Aon, S Cortassa, EY Kim, EF Fang, ... Cell metabolism 27 (3), 667-676. e4, 2018 | 316 | 2018 |
| Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy N Diguet, SAJ Trammell, C Tannous, R Deloux, J Piquereau, N Mougenot, ... Circulation 137 (21), 2256-2273, 2018 | 311 | 2018 |
| Catalysis in the nitrilase superfamily C Brenner Current opinion in structural biology 12 (6), 775-782, 2002 | 279 | 2002 |
| A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects OL Dollerup, B Christensen, M Svart, MS Schmidt, K Sulek, S Ringgaard, ... The American journal of clinical nutrition 108 (2), 343-353, 2018 | 261 | 2018 |
| Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ... Nature metabolism 2 (11), 1265-1283, 2020 | 259 | 2020 |
| Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease. C Brenner, RS Fuller Proceedings of the National Academy of Sciences 89 (3), 922-926, 1992 | 245 | 1992 |
Mark S SchmidtUniversity of Iowa在 uiowa.edu 的电子邮件经过验证
