Mechanism of regulation of the hypoxia‐inducible factor‐1α by the von Hippel‐Lindau tumor suppressor protein K Tanimoto, Y Makino, T Pereira, L Poellinger The EMBO journal, 2000 | 1139 | 2000 |
Hypoxia-inducible factor-1α polymorphisms associated with enhanced transactivation capacity, implying clinical significance K Tanimoto, K Yoshiga, H Eguchi, M Kaneyasu, K Ukon, T Kumazaki, ... Carcinogenesis 24 (11), 1779-1783, 2003 | 318 | 2003 |
Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes K Miyazaki, T Kawamoto, K Tanimoto, M Nishiyama, H Honda, Y Kato Journal of Biological Chemistry 277 (49), 47014-47021, 2002 | 261 | 2002 |
UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α Y Goto, L Zeng, CJ Yeom, Y Zhu, A Morinibu, K Shinomiya, M Kobayashi, ... Nature communications 6 (1), 6153, 2015 | 218 | 2015 |
Polymorphisms of the CYP1A1 and GSTM1 gene involved in oral squamous cell carcinoma in association with a cigarette dose K Tanimoto, S Hayashi, K Yoshiga, T Ichikawa Oral Oncology 35 (2), 191-196, 1999 | 144 | 1999 |
Distinct mechanisms of loss of estrogen receptor α gene expression in human breast cancer: methylation of the gene and alteration of trans-acting factors T Yoshida, H Eguchi, K Nakachi, K Tanimoto, Y Higashi, K Suemasu, ... Carcinogenesis 21 (12), 2193-2201, 2000 | 121 | 2000 |
Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2 H Nakamura, K Tanimoto, K Hiyama, M Yunokawa, T Kawamoto, Y Kato, ... Oncogene 27 (30), 4200-4209, 2008 | 102 | 2008 |
Abnormal FHIT transcripts in human breast carcinomas: a clinicopathological and epidemiological analysis of 61 Japanese cases S Hayashi, K Tanimoto, K Hajiro-Nakanishi, E Tsuchiya, M Kurosumi, ... Cancer research 57 (10), 1981-1985, 1997 | 81 | 1997 |
Aberrant methylation of DPYD promoter, DPYD expression, and cellular sensitivity to 5-fluorouracil in cancer cells T Noguchi, K Tanimoto, T Shimokuni, K Ukon, H Tsujimoto, M Fukushima, ... Clinical cancer research 10 (20), 7100-7107, 2004 | 73 | 2004 |
Activation of the hypoxia-inducible factor-1 in overloaded temporomandibular joint, and induction of osteoclastogenesis M Shirakura, K Tanimoto, H Eguchi, M Miyauchi, H Nakamura, K Hiyama, ... Biochemical and Biophysical Research Communications 393 (4), 800-805, 2010 | 72 | 2010 |
Abnormalities of the FHIT gene in human oral carcinogenesis K Tanimoto, S Hayashi, E Tsuchiya, Y Tokuchi, Y Kobayashi, K Yoshiga, ... British journal of cancer 82 (4), 838-843, 2000 | 71 | 2000 |
Regulation of estrogen receptor α gene mediated by promoter B responsible for its enhanced expression in human breast cancer K Tanimoto, H Eguchi, T Yoshida, K Hajiro-Nakanishi, S Hayashi Nucleic acids research 27 (3), 903-909, 1999 | 69 | 1999 |
Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1α by the von Hippel-Lindau tumor … T Pereira, X Zheng, JL Ruas, K Tanimoto, L Poellinger Journal of Biological Chemistry 278 (9), 6816-6823, 2003 | 68 | 2003 |
Basic helix‐loop‐helix transcription factor DEC1 negatively regulates cyclin D1 UK Bhawal, F Sato, Y Arakawa, K Fujimoto, T Kawamoto, K Tanimoto, ... The Journal of pathology 224 (3), 420-429, 2011 | 67 | 2011 |
Repression of PML nuclear body-associated transcription by oxidative stress-activated Bach2 S Tashiro, A Muto, K Tanimoto, H Tsuchiya, H Suzuki, H Hoshino, ... Molecular and cellular biology 24 (8), 3473-3484, 2004 | 66 | 2004 |
Single nucleotide polymorphism in the hypoxia-inducible factor-1α gene in colorectal carcinoma T Kuwai, Y Kitadai, S Tanaka, T Kuroda, T Ochiumi, S Matsumura, N Oue, ... Oncology reports 12 (5), 1033-1037, 2004 | 64 | 2004 |
Hypoxia inducible factor‐1 influences sensitivity to paclitaxel of human lung cancer cell lines under normoxic conditions L Zeng, S Kizaka‐Kondoh, S Itasaka, X Xie, M Inoue, K Tanimoto, ... Cancer science 98 (9), 1394-1401, 2007 | 62 | 2007 |
Targeted gene delivery to human osteosarcoma cells with magnetic cationic liposomes under a magnetic field K Hirao, T Sugita, T Kubo, K Igarashi, K Tanimoto, T Murakami, ... International journal of oncology 22 (5), 1065-1071, 2003 | 61 | 2003 |
Concise prediction models of anticancer efficacy of 8 drugs using expression data from 12 selected genes T Tanaka, K Tanimoto, K Otani, K Satoh, M Ohtaki, K Yoshida, T Toge, ... International journal of cancer 111 (4), 617-626, 2004 | 54 | 2004 |
Mutation of the von Hippel‐Lindau (VHL) gene in human colorectal carcinoma: Association with cytoplasmic accumulation of hypoxia‐inducible factor (HIF)‐1α T Kuwai, Y Kitadai, S Tanaka, T Hiyama, K Tanimoto, K Chayama Cancer science 95 (2), 149-153, 2004 | 54 | 2004 |