Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2− production H Chun, H Im, YJ Kang, Y Kim, JH Shin, W Won, J Lim, Y Ju, YM Park, ... Nature neuroscience 23 (12), 1555-1566, 2020 | 204 | 2020 |
Aberrant tonic inhibition of dopaminergic neuronal activity causes motor symptoms in animal models of Parkinson’s disease JY Heo, MH Nam, HH Yoon, J Kim, YJ Hwang, W Won, DH Woo, JA Lee, ... Current Biology 30 (2), 276-291. e9, 2020 | 104 | 2020 |
Activation of astrocytic μ-opioid receptor causes conditioned place preference MH Nam, KS Han, J Lee, W Won, W Koh, JY Bae, J Woo, J Kim, E Kwong, ... Cell reports 28 (5), 1154-1166. e5, 2019 | 94 | 2019 |
Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion TY Kim, S Jeon, Y Jang, L Gotina, J Won, YH Ju, S Kim, MW Jang, W Won, ... Experimental & molecular medicine 53 (5), 956-972, 2021 | 67 | 2021 |
Excessive astrocytic GABA causes cortical hypometabolism and impedes functional recovery after subcortical stroke MH Nam, J Cho, DH Kwon, JY Park, J Woo, JM Lee, S Lee, HY Ko, ... Cell reports 32 (1), 2020 | 59 | 2020 |
Visualizing reactive astrocyte-neuron interaction in Alzheimer’s disease using 11C-acetate and 18F-FDG MH Nam, HY Ko, D Kim, S Lee, YM Park, SJ Hyeon, W Won, JI Chung, ... Brain 146 (7), 2957-2974, 2023 | 27 | 2023 |
Signaling mechanisms of μ-opioid receptor (MOR) in the hippocampus: disinhibition versus astrocytic glutamate regulation MH Nam, W Won, KS Han, CJ Lee Cellular and Molecular Life Sciences 78, 415-426, 2021 | 24 | 2021 |
Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis W Won, HJ Choi, JY Yoo, D Kim, TY Kim, YH Ju, KD Park, H Lee, SY Jung, ... Experimental & Molecular Medicine 54 (8), 1188-1200, 2022 | 21 | 2022 |
Hypothalamic GABRA5-positive neurons control obesity via astrocytic GABA M Sa, ES Yoo, W Koh, MG Park, HJ Jang, YR Yang, M Bhalla, JH Lee, ... Nature Metabolism 5 (9), 1506-1525, 2023 | 17 | 2023 |
Adenovirus-induced reactive astrogliosis exacerbates the pathology of Parkinson’s disease H An, H Lee, S Yang, W Won, CJ Lee, MH Nam Experimental Neurobiology 30 (3), 222, 2021 | 14 | 2021 |
Platycodin D prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection in vitro by hindering membrane fusion TY Kim, S Jeon, Y Jang, L Gotina, J Won, YH Ju, S Kim, MW Jang, W Won, ... BioRxiv, 2020.12. 22.423909, 2020 | 7 | 2020 |
Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice H Oh, S Lee, Y Oh, S Kim, YS Kim, Y Yang, W Choi, YE Yoo, H Cho, ... Nature communications 14 (1), 3547, 2023 | 6 | 2023 |
Visualization of reactive astrocytes in living brain of Alzheimer’s disease patient MH Nam, HY Ko, S Lee, YM Park, SJ Hyeon, W Won, SY Kim, HH Jo, ... BioRxiv, 2021.04. 13.439744, 2021 | 5 | 2021 |
Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring JD Lee, W Won, K Kimball, Y Wang, F Yeboah, KM Evitts, C Neiswanger, ... bioRxiv, 2024 | 4 | 2024 |
Mapping Astrocytic and Neuronal μ-opioid Receptor Expression in Various Brain Regions Using MOR-mCherry Reporter Mouse W Won, D Kim, E Shin, CJ Lee Experimental Neurobiology 32 (6), 395, 2023 | 1 | 2023 |
GABA from reactive astrocytes in hypothalamus via monoamine oxidase B causes and exacerbates obesity M Sa, Y Yang, HJ Jang, J Kim, J Kwon, W Won, KD Park, CJ Lee IBRO Reports 6, S126-S127, 2019 | 1 | 2019 |
Mao-b-dependent gaba in the hippocampal reactive astrocytic induces cognitive impairment in animal model of rheumatoid arthritis W Won, SY Jung, CJ Lee IBRO Reports 6, S330, 2019 | 1 | 2019 |
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via excessive H2O2-production H Chun, Y Kim, YJ Kang, H Im, JH Shin, Y Ju, W Won, YM Park, J Lim, ... IBRO Reports 6, S118, 2019 | 1 | 2019 |
Hemoglobin as a peroxidase and drug target for oxidative stress-related diseases W Won, EH Lee, L Gotina, H Chun, JH Lee, U Park, D Kim, TY Kim, J Choi, ... bioRxiv, 2024.05. 21.594979, 2024 | | 2024 |
Ultra-fast genetically encoded sensor for precise real-time monitoring of physiological and pathophysiological peroxide dynamics A Berndt, J Lee, W Won, K Kimball, C Neiswanger, S Schattauer, Y Wang, ... Research Square, 2024 | | 2024 |