Succinate is an inflammatory signal that induces IL-1β through HIF-1α GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ... Nature 496 (7444), 238-242, 2013 | 3474 | 2013 |
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase J Du, Y Zhou, X Su, JJ Yu, S Khan, H Jiang, J Kim, J Woo, JH Kim, ... Science 334 (6057), 806-809, 2011 | 1432 | 2011 |
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine H Jiang, S Khan, Y Wang, G Charron, B He, C Sebastian, J Du, R Kim, ... Nature 496 (7443), 110-113, 2013 | 748 | 2013 |
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2 MA Fischbach, H Lin, L Zhou, Y Yu, RJ Abergel, DR Liu, KN Raymond, ... Proceedings of the National Academy of Sciences 103 (44), 16502-16507, 2006 | 398 | 2006 |
Protein lipidation: occurrence, mechanisms, biological functions, and enabling technologies H Jiang, X Zhang, X Chen, P Aramsangtienchai, Z Tong, H Lin Chemical reviews 118 (3), 919-988, 2018 | 391 | 2018 |
How pathogenic bacteria evade mammalian sabotage in the battle for iron MA Fischbach, H Lin, DR Liu, CT Walsh Nature chemical biology 2 (3), 132-138, 2006 | 378 | 2006 |
Programming peptidomimetic syntheses by translating genetic codes designed de novo AC Forster, Z Tan, MNL Nalam, H Lin, H Qu, VW Cornish, SC Blacklow Proceedings of the National Academy of Sciences 100 (11), 6353-6357, 2003 | 370 | 2003 |
Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation BA Gibson, Y Zhang, H Jiang, KM Hussey, JH Shrimp, H Lin, F Schwede, ... Science 353 (6294), 45-50, 2016 | 336 | 2016 |
Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function S Sadhukhan, X Liu, D Ryu, OD Nelson, JA Stupinski, Z Li, W Chen, ... Proceedings of the National Academy of Sciences 113 (16), 4320-4325, 2016 | 285 | 2016 |
A SIRT2-selective inhibitor promotes c-Myc oncoprotein degradation and exhibits broad anticancer activity H Jing, J Hu, B He, YLN Abril, J Stupinski, K Weiser, M Carbonaro, ... Cancer cell 29 (3), 297-310, 2016 | 267 | 2016 |
Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli G Colak, Z Xie, AY Zhu, L Dai, Z Lu, Y Zhang, X Wan, Y Chen, YH Cha, ... Molecular & Cellular Proteomics 12 (12), 3509-3520, 2013 | 262 | 2013 |
Sirtuins in epigenetic regulation H Jing, H Lin Chemical reviews 115 (6), 2350-2375, 2015 | 245 | 2015 |
The substrate specificity of sirtuins P Bheda, H Jing, C Wolberger, H Lin Annual review of biochemistry 85, 405-429, 2016 | 241 | 2016 |
Protein lysine acylation and cysteine succination by intermediates of energy metabolism H Lin, X Su, B He ACS chemical biology 7 (6), 947-960, 2012 | 238 | 2012 |
Screening and selection methods for large‐scale analysis of protein function H Lin, VW Cornish Angewandte Chemie International Edition 41 (23), 4402-4425, 2002 | 218 | 2002 |
In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes H Lin, MA Fischbach, DR Liu, CT Walsh Journal of the American Chemical Society 127 (31), 11075-11084, 2005 | 214 | 2005 |
A chemoenzymatic approach to glycopeptide antibiotics H Lin, CT Walsh Journal of the American Chemical Society 126 (43), 13998-14003, 2004 | 214 | 2004 |
Investigating the ADP-ribosyltransferase Activity of Sirtuins with NAD Analogues and 32P-NAD J Du, H Jiang, H Lin Biochemistry 48 (13), 2878-2890, 2009 | 213 | 2009 |
Diphthamide biosynthesis requires an organic radical generated by an iron–sulphur enzyme Y Zhang, X Zhu, AT Torelli, M Lee, B Dzikovski, RM Koralewski, E Wang, ... Nature 465 (7300), 891-896, 2010 | 203 | 2010 |
In vitro characterization of IroB, a pathogen-associated C-glycosyltransferase MA Fischbach, H Lin, DR Liu, CT Walsh Proceedings of the National Academy of Sciences 102 (3), 571-576, 2005 | 199 | 2005 |