In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight JE Dahlman, C Barnes, OF Khan, A Thiriot, S Jhunjunwala, TE Shaw, ... Nature nanotechnology 9 (8), 648-655, 2014 | 665 | 2014 |
Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose JS Chahal, OF Khan, CL Cooper, JS McPartlan, JK Tsosie, LD Tilley, ... Proceedings of the National Academy of Sciences 113 (29), E4133-E4142, 2016 | 411 | 2016 |
Proliferation and recruitment contribute to myocardial macrophage expansion in chronic heart failure HB Sager, M Hulsmans, KJ Lavine, MB Moreira, T Heidt, G Courties, ... Circulation research 119 (7), 853-864, 2016 | 394 | 2016 |
Small RNA combination therapy for lung cancer W Xue, JE Dahlman, T Tammela, OF Khan, S Sood, A Dave, W Cai, ... Proceedings of the National Academy of Sciences 111 (34), E3553-E3561, 2014 | 269 | 2014 |
A perspective on the clinical translation of scaffolds for tissue engineering MJ Webber, OF Khan, SA Sydlik, BC Tang, R Langer Annals of biomedical engineering 43, 641-656, 2015 | 238 | 2015 |
RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction HB Sager, P Dutta, JE Dahlman, M Hulsmans, G Courties, Y Sun, T Heidt, ... Science translational medicine 8 (342), 342ra80-342ra80, 2016 | 192 | 2016 |
An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model JS Chahal, T Fang, AW Woodham, OF Khan, J Ling, DG Anderson, ... Scientific reports 7 (1), 252, 2017 | 162 | 2017 |
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy K Jung, T Heishi, OF Khan, PS Kowalski, J Incio, NN Rahbari, E Chung, ... The Journal of clinical investigation 127 (8), 3039-3051, 2017 | 150 | 2017 |
Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature OF Khan, EW Zaia, S Jhunjhunwala, W Xue, W Cai, DS Yun, CM Barnes, ... Nano letters 15 (5), 3008-3016, 2015 | 133 | 2015 |
Genetic and hypoxic alterations of the micro RNA‐210‐ISCU 1/2 axis promote iron–sulfur deficiency and pulmonary hypertension K White, Y Lu, S Annis, AE Hale, BN Chau, JE Dahlman, C Hemann, ... EMBO molecular medicine 7 (6), 695-713, 2015 | 132 | 2015 |
Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression D Yu, OF Khan, ML Suvà, B Dong, WK Panek, T Xiao, M Wu, Y Han, ... Proceedings of the National Academy of Sciences 114 (30), E6147-E6156, 2017 | 121 | 2017 |
Endothelial siRNA delivery in nonhuman primates using ionizable low–molecular weight polymeric nanoparticles OF Khan, PS Kowalski, JC Doloff, JK Tsosie, V Bakthavatchalu, CB Winn, ... Science advances 4 (6), eaar8409, 2018 | 97 | 2018 |
Endothelialized biomaterials for tissue engineering applications in vivo OF Khan, MV Sefton Trends in biotechnology 29 (8), 379-387, 2011 | 96 | 2011 |
Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche M Krohn-Grimberghe, MJ Mitchell, MJ Schloss, OF Khan, G Courties, ... Nature biomedical engineering 4 (11), 1076-1089, 2020 | 93 | 2020 |
Ionizable amphiphilic dendrimer‐based nanomaterials with alkyl‐chain‐substituted amines for tunable siRNA delivery to the liver endothelium in vivo OF Khan, EW Zaia, H Yin, RL Bogorad, JM Pelet, MJ Webber, I Zhuang, ... Angewandte Chemie International Edition 53 (52), 14397-14401, 2014 | 90 | 2014 |
Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β–induced Serpine1 JV McCann, L Xiao, DJ Kim, OF Khan, PS Kowalski, DG Anderson, ... The Journal of clinical investigation 129 (4), 1654-1670, 2019 | 78 | 2019 |
Endothelial cell behaviour within a microfluidic mimic of the flow channels of a modular tissue engineered construct OF Khan, MV Sefton Biomedical microdevices 13, 69-87, 2011 | 78 | 2011 |
Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo Y Dong, AA Eltoukhy, CA Alabi, OF Khan, O Veiseh, JR Dorkin, ... Advanced healthcare materials 3 (9), 1392, 2014 | 70 | 2014 |
MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment RA Wilson, C Espinosa-Diez, N Kanner, N Chatterjee, R Ruhl, C Hipfinger, ... Nature communications 7 (1), 13597, 2016 | 64 | 2016 |
BOLA (BolA Family Member 3) deficiency controls endothelial metabolism and glycine homeostasis in pulmonary hypertension Q Yu, YY Tai, Y Tang, J Zhao, V Negi, MK Culley, J Pilli, W Sun, K Brugger, ... Circulation 139 (19), 2238-2255, 2019 | 61 | 2019 |