The immunopathology of sepsis and potential therapeutic targets T van der Poll, FL van de Veerdonk, BP Scicluna, MG Netea Nature Reviews Immunology 17 (7), 407-420, 2017 | 1552 | 2017 |
The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia TJ Schuijt, JM Lankelma, BP Scicluna, FS e Melo, JJTH Roelofs, ... Gut 65 (4), 575-583, 2016 | 758 | 2016 |
Incidence, risk factors, and attributable mortality of secondary infections in the intensive care unit after admission for sepsis LA van Vught, PMCK Klouwenberg, C Spitoni, BP Scicluna, MA Wiewel, ... Jama 315 (14), 1469-1479, 2016 | 536 | 2016 |
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis SC Cheng, BP Scicluna, RJW Arts, MS Gresnigt, E Lachmandas, ... Nature immunology 17 (4), 406-413, 2016 | 530 | 2016 |
Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study BP Scicluna, LA Van Vught, AH Zwinderman, MA Wiewel, EE Davenport, ... The Lancet Respiratory Medicine 5 (10), 816-826, 2017 | 451 | 2017 |
Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients TAM Claushuis, LA van Vught, BP Scicluna, MA Wiewel, ... Blood, The Journal of the American Society of Hematology 127 (24), 3062-3072, 2016 | 307 | 2016 |
The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunity J Domínguez-Andrés, B Novakovic, Y Li, BP Scicluna, MS Gresnigt, ... Cell metabolism 29 (1), 211-220. e5, 2019 | 299 | 2019 |
Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction CR Bezzina, R Pazoki, A Bardai, RF Marsman, JSSG De Jong, MT Blom, ... Nature genetics 42 (8), 688-691, 2010 | 241 | 2010 |
Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy K Pilichou, CA Remme, C Basso, ME Campian, S Rizzo, P Barnett, ... Journal of Experimental Medicine 206 (8), 1787-1802, 2009 | 236 | 2009 |
A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission BP Scicluna, PMC Klein Klouwenberg, LA van Vught, MA Wiewel, ... American journal of respiratory and critical care medicine 192 (7), 826-835, 2015 | 205 | 2015 |
A molecular host response assay to discriminate between sepsis and infection-negative systemic inflammation in critically ill patients: discovery and validation in independent … L McHugh, TA Seldon, RA Brandon, JT Kirk, A Rapisarda, AJ Sutherland, ... PLoS medicine 12 (12), e1001916, 2015 | 199 | 2015 |
Biomarkers in sepsis TSR Van Engelen, WJ Wiersinga, BP Scicluna, T van der Poll Critical care clinics 34 (1), 139-152, 2018 | 183 | 2018 |
36th international symposium on intensive care and emergency medicine: Brussels, Belgium. 15-18 March 2016 RM Bateman, MD Sharpe, JE Jagger, CG Ellis, J Solé-Violán, ... Critical care 20, 13-182, 2016 | 172 | 2016 |
Functional NaV1.8 Channels in Intracardiac Neurons: The Link Between SCN10A and Cardiac Electrophysiology AO Verkerk, CA Remme, CA Schumacher, BP Scicluna, R Wolswinkel, ... Circulation research 111 (3), 333-343, 2012 | 167 | 2012 |
Apc-mutant cells act as supercompetitors in intestinal tumour initiation SM van Neerven, NE de Groot, LE Nijman, BP Scicluna, MS van Driel, ... Nature 594 (7863), 436-441, 2021 | 150 | 2021 |
Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice L Fabritz, MG Hoogendijk, BP Scicluna, SCM Van Amersfoorth, ... Journal of the American College of Cardiology 57 (6), 740-750, 2011 | 137 | 2011 |
The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium CA Remme, AO Verkerk, WMH Hoogaars, WTJ Aanhaanen, BP Scicluna, ... Basic research in cardiology 104, 511-522, 2009 | 136 | 2009 |
Admission hyperglycemia in critically ill sepsis patients: association with outcome and host response LA van Vught, MA Wiewel, PMCK Klouwenberg, AJ Hoogendijk, ... Critical care medicine 44 (7), 1338-1346, 2016 | 121 | 2016 |
Understanding heterogeneity in biologic phenotypes of acute respiratory distress syndrome by leukocyte expression profiles LDJ Bos, BP Scicluna, DSY Ong, O Cremer, T van Der Poll, MJ Schultz American journal of respiratory and critical care medicine 200 (1), 42-50, 2019 | 116 | 2019 |
Myocardial injury in patients with sepsis and its association with long-term outcome JF Frencken, DW Donker, C Spitoni, ME Koster-Brouwer, IW Soliman, ... Circulation: Cardiovascular Quality and Outcomes 11 (2), e004040, 2018 | 109 | 2018 |