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Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE modENCODE Consortium, S Roy, J Ernst, PV Kharchenko, P Kheradpour, ... Science 330 (6012), 1787-1797, 2010 | 1086 | 2010 |
Design and analysis of ChIP-seq experiments for DNA-binding proteins PV Kharchenko, MY Tolstorukov, PJ Park Nature biotechnology 26 (12), 1351-1359, 2008 | 1083 | 2008 |
Comprehensive analysis of the chromatin landscape in Drosophila melanogaster PV Kharchenko, AA Alekseyenko, YB Schwartz, A Minoda, NC Riddle, ... Nature 471 (7339), 480-485, 2011 | 985 | 2011 |
The long noncoding RNAs NEAT1 and MALAT1 bind active chromatin sites JA West, CP Davis, H Sunwoo, MD Simon, RI Sadreyev, PI Wang, ... Molecular cell 55 (5), 791-802, 2014 | 666 | 2014 |
Comparative analysis of metazoan chromatin organization JWK Ho, YL Jung, T Liu, BH Alver, S Lee, K Ikegami, KA Sohn, A Minoda, ... Nature 512 (7515), 449-452, 2014 | 421 | 2014 |
CpG islands recruit a histone H3 lysine 36 demethylase NP Blackledge, JC Zhou, MY Tolstorukov, AM Farcas, PJ Park, RJ Klose Molecular cell 38 (2), 179-190, 2010 | 357 | 2010 |
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate AA Chakraborty, T Laukka, M Myllykoski, AE Ringel, MA Booker, ... Science 363 (6432), 1217-1222, 2019 | 356 | 2019 |
SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation X Wang, RS Lee, BH Alver, JR Haswell, S Wang, J Mieczkowski, Y Drier, ... Nature genetics 49 (2), 289-295, 2017 | 323 | 2017 |
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer S Raghavan, PS Winter, AW Navia, HL Williams, A DenAdel, KE Lowder, ... Cell 184 (25), 6119-6137. e26, 2021 | 288 | 2021 |
Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin NC Riddle, A Minoda, PV Kharchenko, AA Alekseyenko, YB Schwartz, ... Genome Research 21 (2), 147-163, 2011 | 282 | 2011 |
Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway Z Jagani, EL Mora-Blanco, CG Sansam, ES McKenna, B Wilson, D Chen, ... Nature medicine 16 (12), 1429-1433, 2010 | 262 | 2010 |
MNase titration reveals differences between nucleosome occupancy and chromatin accessibility J Mieczkowski, A Cook, SK Bowman, B Mueller, BH Alver, S Kundu, ... Nature communications 7 (1), 11485, 2016 | 250 | 2016 |
A novel roll-and-slide mechanism of DNA folding in chromatin: implications for nucleosome positioning MY Tolstorukov, AV Colasanti, DM McCandlish, WK Olson, VB Zhurkin Journal of molecular biology 371 (3), 725-738, 2007 | 247 | 2007 |
Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters MY Tolstorukov, CG Sansam, P Lu, EC Koellhoffer, KC Helming, BH Alver, ... Proceedings of the National Academy of Sciences 110 (25), 10165-10170, 2013 | 210 | 2013 |
Diminished efficacy of programmed death-(ligand) 1 inhibition in STK11-and KEAP1-mutant lung adenocarcinoma is affected by KRAS mutation status B Ricciuti, KC Arbour, JJ Lin, A Vajdi, N Vokes, L Hong, J Zhang, ... Journal of Thoracic Oncology 17 (3), 399-410, 2022 | 205 | 2022 |
Nature and function of insulator protein binding sites in the Drosophila genome YB Schwartz, D Linder-Basso, PV Kharchenko, MY Tolstorukov, M Kim, ... Genome research 22 (11), 2188-2198, 2012 | 203 | 2012 |
Impact of sequencing depth in ChIP-seq experiments YL Jung, LJ Luquette, JWK Ho, F Ferrari, M Tolstorukov, A Minoda, ... Nucleic acids research 42 (9), e74-e74, 2014 | 200 | 2014 |
Association of high tumor mutation burden in non–small cell lung cancers with increased immune infiltration and improved clinical outcomes of PD-L1 blockade across PD-L1 … B Ricciuti, X Wang, JV Alessi, H Rizvi, NR Mahadevan, YY Li, A Polio, ... JAMA oncology 8 (8), 1160-1168, 2022 | 172 | 2022 |
Histone variant H2A. Bbd is associated with active transcription and mRNA processing in human cells MY Tolstorukov, JA Goldman, C Gilbert, V Ogryzko, RE Kingston, PJ Park Molecular cell 47 (4), 596-607, 2012 | 151 | 2012 |